The Bones Of The Human Body

An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.

in the development and onset of this disease. Sex hormones, such as estrogen previously mentioned, as well as testosterone in men can help build and maintain healthy bones. When these hormone levels decrease, which is not uncommon in old age, the chance for osteoporosis increase significantly.

Now a days there are hundreds of shows on television that can make sinking into the couch for a weekend bender truly difficult. You can usually tell by the first ten or twenty minutes if it is a show you want to invest your time into or not. Finding your favorite genre seems to help when making this decision from the array of shows available. Due to this show being in its final season I found it only fitting to explain why the criminal and forensic drama known as Bones is an all-time favorite of mine. Bones is an entertaining spin on forensic science shown on Fox. One of the more suspenseful episodes in this series was The Grave Digger episode where Dr. Temperance Brennen and Dr. Jack Hodgins

Osteoporosis develops when the remodeling cycle, which is when the disruption of the bone resorption and bone formation occurs. The imbalance of the remodeling cycle causes osteoporosis. Hormones, cytokines, and paracrine stromal-cell interactions affect the osteoclast’s processes, which includes proliferation, maturation, fusion and activation. The osteoclasts are controlled by the interaction between several interleukins, tumor necrosis factor, transforming growth factor-beta, prostaglandin E2 and hormones. The glucocorticoid-induced osteoporosis is related to increased destruction of osteocytes. Glucocorticoid increase receptor activator of nuclear factor ligand (RANKL) effect and inhibit osteoprotegerin (OPG) production through

Bone is a living tissue and made up of cartilage. Fibrodysplasia ossificans progressiva bone appears as normal bone tissue, but it develops in the wrong places. Osteogenesis and ossification are medical terms which refer to the formation of bone. Most bones in the human body grow and heal up after a break through endochondral bone formation, which is how FOP bones grow. Cartilage forms first and then the bone will eventually take the place of cartilage.

There are approximately two hundred six bones in our body and they're essential in our life. Bones consists of osseous tissue, nervous tissue, and epithelial and muscle tissue. Examples are the femur, humerus, clavicle, and sternum. The bones have many different functions in our bodies, but basically, their main functions are to provide support and protection for the body. Bones provide a framework that supports our body and bones such as skull, vertebrae and rib cage try to prevent internal organs from injuries. Also, bones enable movement by providing points of attachment for muscles and they produce blood cells, also known as hematopoiesis in the red marrow. Lastly, bones store minerals, such as calcium and phosphorus for different cellular activities and store lipids in adipose cells of the yellow marrow as an energy reservoir. There are different shapes and textures of bones. Bones can be flat, such as scapula and sternum, or irregular like the sphenoid bone and vertebra. Also, bones can be short or long. Examples of short bones are the carpal bone and talus and long bones are ulna, femur, and radius. In terms of texture, bones can be compact or spongy. Compact bones are dense and heavy while spongy bones are porous and light. Both types of bones are connective tissues. Usually compact bones are the out layer of a bone and spongy bones are the internal portion of the bone.

Osteoporosis occurs when bones lose their strength and density. They become fragile, weak, and brittle, this means that the bones are more likely to fracture. Osteoporosis particularly affects women after menopause and in their later years. However, some men may also be affected. Activity and a healthy diet rich in calcium and vitamin D can help prevent osteoporosis. It affects one of every two women and one out of every five men, according to Centers for Disease Control and Prevention (CDC).

Low oestrogen in women: Oestrogen plays a vital role in maintaining bone strength. Low oestrogen is one of the most common causes of osteoporosis in women. The gradual reduction of bone density accelerates after menopause when women experience a vast drop in the levels of oestrogen they produce. Over time, the risk of osteoporosis and fracture increases as older women lose more bone than they replace.

According to Judith (2010), Osteoporosis is a loss of the reabsorption in the bones by way of calcium, plasma, and phosphate. Estrogen production helps bones metabolism by stimulating osteoblastic activity and limiting osteoclastic effects of the parathyroid hormone. It develops when the new formation of bones fall behind in the reabsorption process (Judith, 2010). In simpler terms, it’s a loss of bone mass due to a metabolic bone disorder affected by the rate of bone resorption advances while the rate of the bone formation reduces. According to Judith (2010), the bones end up losing calcium, phosphates and end up brittle making them prone to fractures and further complications (P . 236).

Studies have shown that both estrogen and raloxifene, a Selective Estrogen Receptor Modulator, can prevent the loss of bone mass in postmenopausal women. Alendronate, a bisphosphonate is an alternative to estrogen for bone protection. Calcitonin is another treatment used by women for osteoporosis. This drug has been shown to slow bone breakdown and also may reduce the pain associated with osteoporotic fractures. Treatments under investigation include other bisphosphonates, sodium fluoride, para-thyroid hormone, vitamin D metabolites, and other selective estrogen receptor modulators.

Other hormone imbalances also cause Osteoporosis. Hormones including parathyroid hormone and growth hormone are also important in regulating bone density. If too much parathyroid hormone is produced, it results in calcium loss in the urine. Growth hormone is needed to build up strong bones, and so they become weak with a lack of growth hormone.

We did it. We finally met and I was going to stay for an entire week to meet his family and spend time with him. It was the greatest adventure of my life. To be completely honest, this adventure doesn't have an ending. My adventure with him won't ever be over. This is forever. The obstacles will never stop, they almost never stop. From page 30 until the final chapters of Bone, The Bones faced obstacles and always stuck together, even though they weren't always there with each other in person. My adventure isn't over and until the day I die my adventure won't ever be over.

Dando Vida words at the bottom are the steps to giving life to earth’s beauty.

Bone serves the organism at multiple levels: As a system, bones permit the organism to locomote effectively and to maintain posture by bearing loads without deformation, by providing rigid attachment sites for muscles and acting as a system of levers to amplify small movements. As an organ, bones protect the viscera and house the hemopoietic tissue (red marrow). As a tissue, bones serve as a reservoir of readily mobilizable calcium, an

Have you ever thought about how humans would be without bones? They would not be able to function the way that they do now if it did not have bones. The skeletal system is a highly important system in the human body, it functions as support, protection, and creation of red blood cells. This system is composed of bones and joints, an average adult contains 206 bone and an average child contains 270 bones because as a person grows the bones fuse together to create a single bone. The skeletal system is divided in to two major category: the axial skeleton and the appendicular skeleton. The axial skeleton has 80 bones in the midline axis which contains the bones of the head and the trunk; while the appendicular axis has 126 bones which include the bones from the limbs, pectoral and pelvic regions. There are only a few select bones that are mainly affected by the Paget disease these include the pelvis and the tibia which belong to the appendicular axis; however, other bones that could be affected are the femur, spine, skull, clavicle, and fibula.