The Case For The Vaccine For Brucella Abortus Strain Rb 51, Causing Agent Of Brucellosis Essay

The history of vaccinations begin with Edward Jenner, the country doctor from Gloucestershire who found, growing on cows, a nearly harmless virus the protected people from smallpox. Jenner’s vaccine was safer, more reliable, and more durable than variolation, and it is still the only vaccine to have eliminated its reason for being-in 1980, when the World Health Organization (WHO) declared the disease extinct. For nearly a century and a half, smallpox was the only vaccine routinely administered, and it saved millions of lives . But the controversy that marked the return of the vaccine, amid bioterrorism hysteria in 2002, was only the latest twist in the remarkable, mysterious life of vaccines.

Throughout history, vaccinations have been used to help the prevention of infectious diseases; some of which can produce serious illnesses, crippling disabilities, and ultimately be the cause of death. There is evidence of ancient culture’s attempting to treat transmittable diseases with various forms of inoculations. Developments in the research of vaccinations increased during the mid-twentieth century because of the established of more advanced laboratories, improved equipment, and new innovations. The progression of medicine during history has helped further the development of research into vaccinations. Several cultural, ethical, and religious issues have resulted from the development and use of vaccinations in our society. The topic of vaccinations has caused a strong debate amongst our culture about the safety and danger of treating infectious diseases with such methods.

Vaccines are one of the most unknown topics for people. They inject their body with chemicals without regard to what is going into their body and how it is affecting it. I, also, am guilty of doing this. To remove my ignorance and inform others, I am going to research more on this topic. By writing this paper, I am hoping to shed more light on this unfamiliar concept.

Edward Jenner and the Discovery of Vaccines Edward Jenner (1749-1823) trained in London, under John Hunter, and was an army surgeon for a period of time. After that, he spent his whole career as a country doctor in his home county, Gloucestershire (West of England). His research was based on careful case studies and clinical observation more than a hundred years before scientists could explain what viruses and diseases actually were. His innovative new method was successful to such an extent that by 1840 the British government had banned alternative preventive treatments against smallpox. [IMAGE]

Thesis: Immunizations are one of the most important medical advances in history. They have severely reduced the effects of dozens of viral infections and everyone should consider getting immunized.

Vaccines change over time as science makes advancements and diseases processes evolve and emerge. Around 400 BC, Hippocrates recognized the now preventable diseases, such as diphtheria and mumps (Immunization Act Coalition, 2015). The first effort to immunize dates back to the 1100’s when children were inoculated with scabs from individuals who recently had small pox, with a technique coined as variolation. Then in 1796, Edward Jenner successfully created the first small pox vaccine (Immunization Act Coalition, 2015).

In the book, “Survival of the Sickest”, Sharon Moalem forms the basis of how vaccine originated to become a way of combatting the most dangerous diseases in the world. It began with a discovery from a man named Edward Jenner, a doctor from Gloucestershire county in England, where he began to understand a strange pattern when people who were immune to cowpox were struggling with smallpox and vice-versa. He started to test his findings through a small experiment where he injected cow pox into a group of young children and he was surprised to see that their bodies built immunity towards smallpox and supported his findings on the bizarre immunity of people towards either the smallpox or the cowpox but not to both. The rest of the chapter explains complex concepts

Mandatory vaccination continues to be a contentious subject in the United States, even though extensive evidence proves inoculation prevents certain diseases. According to A. Plotkin & L. Plotkin (2011), the evolution of the first vaccine commenced in the 1700’s when a physician named Edwards Jenner discovered that cowpox protected individuals from one of the deadliest diseases termed smallpox. The precise virus Jenner used is unclear; however, it was espoused in the extermination of smallpox worldwide. The researchers further explained, the unearthing of the subsequent vaccine known as chicken cholera occurred approximately 80 years later by Louise Pasteur. Ever since, copious vaccines such as rabies, yellow fever, varicella, pneumococcal, mumps and recently HPV have been introduced.

The requirement by the United States for childhood vaccines and immunizations has been a long standing debate amongst both families and communities within the United States. Throughout this persistent debate there have been influential and iconic spokesmen and women for and against the vaccination of children. To better understand why this is such a thoroughly argued topic of discussion throughout the country, you must first delve into the immune system and garner an understanding of how our bodies fight disease, as well as, what constitutes a vaccine.

Ainsworth, Steve. “Vaccination: Where It All Began.” Academic Search Premier, EBSCOhost. Accessed January 31, 2016. http://web.b.ebscohost.com/ehost/detail/detail?vid=12&sid=bd75326f-a5ed-44b4-99be-e95390625d8a%40sessionmgr114&hid=107&bdata=JnNpdGU9ZWhvc3QtbGl2ZQ%3d%3d#AN=51192088&db=aph.

The disease has been an enemy of a human ever since it first appeared. In fact, humankind has been at war with the disease for most of history, often at the losing end. However, the principle of immunization equalized this adversarial relationship. The concept of vaccination has been one of the most significant medical advancements in history because it has prevented the onset of deadly diseases, has eradicated previously malignant maladies, and has improved human life by removing fear of acquiring such contagious afflictions.

The first vaccination invented was for smallpox in 1798 by a man named, Edward Jenner (Kotz, 2009). His work was herald as the leading scientific effort to control a transmittable virus by the measured consumption of a vaccination. Today, current medication is founded on Pasteur’s germ philosophy of infection (Link, 2005). Scientists now have vaccinations for almost everything from vitamin vaccinations to vaccines preventing illnesses.

First, in 1796, a doctor named Edward Jenner performed the very first vaccination. “Taking pus from a cowpox lesion on a milkmaid’s hand, Jenner inoculated an eight-year-old boy, James Phipps. Six weeks later Jenner variolated two sites on Phipps ' arm with smallpox, yet the boy was unaffected by this as well as subsequent exposures” (Minna & Markel, 2005)& (Cave, 2008). The first vaccination allowed people to recognize that it was beneficial for their health. It provided the base for the rest of the variations of vaccinations to come. Vaccinations began with the notion that it is rooted in the science of immunology. Throughout history, there have been many variations of this first vaccine for things such as small pox, mumps, malaria and guinea worm. (The College of Physicians of Philadelphia, n.d.)

Brucella abortus is zoonotic, which can cause brucellosis in both cattle and human. The geographical distribution of both human and bovine brucellosis is wide and is constantly changing; this not only results in great economic loss in animal production, but also compromises human health. Although bovine brucellosis can be prevented by vaccine and elimination of the infected cattle, there is no licensed vaccine for human at the moment.

Our current society is surrounded by the debatable usage of vaccines and its importance around the world. Since the introduction of immunizations, many diseases have been decreased and even eradicated from humanity. Even though this is true, serious side effects along with lifelong illnesses follow the temporary cure of viruses. A vaccine is a substance that delivers immunity against viruses and is used to stimulate the construction of antibodies. Vaccines are prepared from the disease itself treated to perform as an antigen without inducing the disease (Vaccines). These inoculations are used worldwide and various unknown infections have been speculated as the originations for them. Vaccines were originated as an alternative to cure viruses among people but the harmful symptoms, unknown links to incurable