The Cognitive Deficits Caused By Urbach Wiethe Disease Essay

5. What is the prevalence and prognosis of this condition? Is it an inheritable (genetic) condition/disease? (1 point)

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

There are many reasons that Mrs. Yowell may have impaired mental functioning (see Table 1). The first and easiest reason to rule out would be a urinary tract infection (UTI). A urine sample can show if there are white blood cells (indicating infection) present in the urine. The increased levels of bacteria in an elderly person’s body can cause toxicity which leads to the altered mental status (Midthun, 2004). Most noted changes are confusion, agitation and lethargy.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

This syndrome is not very common, because it is a rare condition. Its prevalence is not certain, but the proximate amount is 5 to 10 individuals per million newborns. Research workers appraise that there are approximately 200 to 300 individuals around the world who have this disorder. It is observed with equivalent recurrence in both males and females over all ethnic groups.

Reckless behavior early in life can affect the rest of your life dramatically. Whether it is drinking too much, use of illegal drugs, or even just a simple vehicle accident, it can cause brain damage which can lead to dementia. Dementia isn’t necessarily a disease but rather terminology to describe a set of symptoms. “Severe impairment in intellectual capacity and personality, often due to damage to the brain” (Gazzaniga, Grison, & Heatherton, 2015). In other words, dementia comes with an inability to process surroundings, a difference in character, and, depending in severity, complete memory loss. This loss is because nerve cells in the parts of the brain that are responsible for cognition, like the cerebellum (Molinari, 2002), have been damaged and can no longer function normally. There are many types of dementia, such as, Alzheimer’s, the most common, as well as many others that differ in symptoms. Though many kinds of dementia normally end in pain, suffering and often death, there is no cure. Dementia is a neurocognitive disorder that can affects one’s life drastically, because of memory loss, an inability to preform everyday activities, and personality changes.

Dementia is a term used to describe symptoms associated with decline in memory or other

     Recent studies show that this syndrome may be associated with changing craniofacial and skeletal muscle metabolism, such as blood flow, which causes the chronic fatigue and severe weakness. Another hypothesis is that an infectious trauma to the body, such as a virus, triggers the illness. However, with this syndrome being new, no specific virus has been identified. There is though a plot study that shows that there is possible inherited tendency toward the disease. This disease/syndrome has increased

This syndrome is from a mutation of a gene on chromosome 15 and this causes problems in the production of fibrillin-1 which is a protein that is an important part of connective tissue. The name for the gene is FBN1. Basically, it is the “glue” that helps to support the tissues in the human body. A child born to a parent with this syndrome has a 50% of having it. However, in the remaining 25%, neither parent has the disease which gives them a 1 in 10,000 chance of having a child with this disorder. When a child of two unaffected parents is born with it then the genetic mutation occurs in either the egg or sperm cell at the time of conception.

This disease is genetically inherited and is a dominant characteristic, therefore unfortunately the offspring of a victim has 50% chance of inheriting the disease.

Dementia is a type of disorder that affects the central nervous system. It’s not a disease itself but a group of symptoms that characterize disease and conditions. It’s commonly defined as a decline in intellectual functioning that is severe enough to interfere with the ability to perform routine activities. It causes significant loss of intellectual abilities, such as memory capacity, severe enough to interfere with social or occupational functioning. Dementia‘s a general term that also includes specific disorders like vascular dementia as well as others.

The genetic mutations that cause this disease are more commonly found in the Ashkenazi people with a Jewish heritage than those with other backgrounds. French-Canadian communities of Quebec, the Old Order amish community in Pennsylvania, and the Cajun population of Louisiana, are more responsible for the mutation for this disease. The HEXA has been discovered for the cause of Tay Sachs. The gene provides for making part of an enzyme, which is cause, "beta-hexosaminidase A", which plays an important role in the spinal cord and brain. Disruptions in the HEXA gene messes with the activity of beta-hexosaminidase A, and then prevents the enzyme from breaking down GM2 ganglioside. This results the the substance accumulating to toxic levels in the neurons in the brain and spinal cord. Continuous damage caused by the build up of GM2-ganglioside leads to the destruction of the neurons and thus causes the signs and symptoms of Tay-Sachs

Over three million people every year are diagnosed with a group of conditions, called dementia. Dementia is not a disease itself, but instead is a term that is used to describe a range of symptoms. Actual diseases, such as Alzheimer’s disease and strokes, can cause dementia. Alzheimer’s disease is the most common cause for dementia; it accounts for sixty to eighty percent of all dementia cases. Incorrectly, dementia is sometimes called “senility.” This is incorrect because the term “senility” portrays dementia and its symptoms as normal signs of aging, which is not the case.