The Commercialization Of Flumist ( Medimmune ) The First Influenza Vaccine

Additionally, as many as 500,000 chicken eggs per day are needed for the process. Influenza viruses are injected into chicken egg embryos, where they are allowed to incubate and multiply for several days. A machine extracts the virus from the egg, which is then purified and chemically killed and made into the vaccine. (Tenpenny, 2008, Davidson, 2007-2009, Offit, 2008).

Every year, millions of people start talking about the influenza virus and getting their vaccines as the flu season approaches, which starts around the October-November period and reaches its peak between December and March. Therefore, public health officials around the world- and in the U.S in particular- are constantly challenged by properly preparing for the annual influenza dilemma, given that this viruses, and other respiratory viruses, are a serious health threat to the U.S population and the world as a whole. Furthermore, what makes the influenza virus even more challenging to control is that it can mutate rapidly and reassort to form new strains, having the ability to reside in multiple animal hosts. In fact, many scientists and researchers have been doing in-depth intensive research so as to understand the mechanism behind this unique characteristic of the virus, try to find new ways to control it, and explore different areas of protection and vaccination.

The CDC's ad campaign promoting influenza vaccinations has a widespread appeal to many audiences due to its use of several proven persuasive techniques. Through the use of association, flattery, and universal appeal, as well as a variety of strategies, the ad campaign is highly convincing and is able to reach many audiences.

With influenza vaccination rates remaining low in the HCP population, there has recently been an increased emphasis on improving vaccination rates among HCPs. Low influenza vaccination rates have caused many healthcare facilities to initiate and mandate employees to receive the influenza vaccine. Research has proven to reduce morbidity and mortality among patients in healthcare facilities as well as decrease illness and absenteeism among HCPs (Sickbert & Weber, 2013). For these reasons multiple professional organizations are recommending an annual influenza vaccine for all HCPs, if medically suitable for this vaccination. Requiring a physician waiver for non-suitable HCP, all non-suitable HCP are expected or required to wear a mask in direct patient care areas.

Six different batches of recombinant HVT-H5 avian influenza vaccines obtained from office of receiving samples in central laboratory for evaluation of veterinary biologics (CLEVB), Abbasia.

The influenza vaccination in not only beneficial to recipients but also those that come in contact with the individuals exposed to or at risk for contracting influenza. Health care workers are at a constant risk of exposure to various diseases and illness including influenza. An emergency such as a vaccination shortage for influenza will not only affect at risk individuals but spread rapidly to all those exposed without knowledge or a-symptomatic at time of encounter. Health care workers will be exposed in physician offices, hospitals, emergency care or urgent care centers with heightened possibility of spreading the illness (CDC, 2015). Health care workers are not limited to the obvious: physicians or nurses but also, therapists, EMS,

Everywhere you look you see ads on the tv, at the store, on the highway, even in school you will sometimes see some sort of advertising one ad you will see more frequently during flu season are ads put out by the center for disease control but what makes an add effective to a certain audience? In America alone an average of between 5 and 20 percent of americans will be infected with the influenza virus per year. The CDC has been effectively running their flu vaccination for many years now but the question is what makes these adds effective or ineffective? The three adds benefits of vaccination, quiz add, and travel ad each have a certain techniques they use to promote vaccination.

To answer my research question I will first review literature on flu vaccines from conventional sources such as the Center for Disease Control and National Institute for Health. I will then review other material available on the Internet written by doctors that do not agree with the conventional

Influenza is responsible for hospitalizations and deaths in the United States. Prevention through vaccination is one way to circumvent illnesses, hospitalizations and deaths. Those persons who were more susceptible fall into the categories of 6 months to 4 years of age and 65 years and older. According to CDC (2013), the 2012-13 influenza season was characterized as a moderately severe season based on the surveillance data. Regardless of suggestions and encouragements of schools and places of employment for individuals to be vaccinated against the flu, fewer than half the persons in the United States each year are inoculated against this disease. Influenza vaccines are now widely used to reduce the burden of annual epidemics of influenza virus infections (Cowling, et al., 2016).

Each year, there is an estimated 36,000 deaths associated with influenza, about 1,250 from the United States. Influenza (also known as the flu) is a highly contagious respiratory illness that attacks the upper respiratory tract. In some cases, it can cause a mild to severe illness, but in other in others it can lead to death. Many try to eliminate getting the flu at all by getting an influenza vaccine. The influenza vaccine has produced controversy all over the United States, as some say it is highly dangerous, while most medical professionals strongly advise it. Although it may be the greatest chance of not catching influenza, it can come with serious complications and side effects that can damage or even kill a person. The current debate on the topic questions whether the vaccine is safe, if it’s necessary, and if it actually works.

Illnesses have long haunted the human race. As long as these illnesses have existed, humans have developed ways to cure themselves, beginning with simple herbs and proceeding as far as vaccines and complex medicines. One cure that long eluded scientists was that of the influenza virus. Now, the influenza vaccine, or flu shot, saves thousands of lives a year and helps prevent serious complications resulting from influenza infection.

According to Healthy People 2020 a goal of theirs is to “increase immunization rates and reduce preventable infections.” The influenza virus is one of these preventable infections, which can cause serious harm to patients. The influenza virus is known as the “flu.” Everyone in his or her life has had some experience with the flu, whether that is himself or herself or a family member. What if there was a way to ensure people from contracting a strain of the influenza virus? Well, thanks to technology and medical research there is.

About 5.4 million American people have Alzheimer’s, 3.5 million have autism and flu claims 36000 people annually. These statistics emphasize the importance of the treatment of such disorders. Thus, I would increase funding for projects like Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative and Universal Flu Vaccine. The BRAIN project is decoding the role of neurons in the thoughts, memories and the perception of sensory experience. More funding can result in treatment of mental disorders, like Alzheimer’s, ADHD, autism, schizophrenia, and depression, affecting both young and old. Moreover, because of the continuous evolution of flu virus, annual administration of modified flu shots costs $87 billion. The Universal

The role of hemagglutinin (HA) , which is one of the abundant & immunodominant glycoprotein on the surface of the influenza virus ,is very important as an immunogen in anti-influenza vaccines (Gamblin & Skehel.,2010). HA is a major glycoprotein in the viral lipid envelope membrane with a distal globular head that mediates host-cell receptor binding followed by a membrane-proximal stalk domain which directs fusion of viral envelope with the host cell(Kaminski &Lee ,2011). The current split-virus vaccines predominantly induce antibodies to the surface glycoprotein like HA ,NA . Due to antigenic drift ,the surface glycoproteins undergo mutations, therefore the three influenza strains are included in seasonal IIV (influenza A(H1N1) and A(H3N2) and influenza B) which are evaluated for their ability to generate neutralizing antibodies against the circulating influenza strains (Waffarn E. & Baumgarth N.,2011). . After vaccination with inactivated Influenza vaccine , it results in both local and systemic responses generation. .Within 2 weeks of vaccination, 90% of vaccines found to have protective antibody titres (Cox RJ.1994) .In humans, hemagglutinin specific effector T-cells are found to be major proliferating subsets of T-cells which are seen after stimulation by HA molecule (Novak et al 1999).

Another claim against immunization is personal opposition to big pharmaceutical companies. Some believe vaccines are charged to patients solely for profit. This pharmaceutical profit-motive can call into question product safety and integrity. The overwhelming majority of vaccines are not highly profitable though (Lam). Due to the massive investment of time and funds required to create vaccines, coupled with only marginal returns on this investment, pharmaceutical corporations do not focus on them. As result, nonprofit health organizations and political agencies such as the CDC, and the WHO, generally lead the charge in vaccine development. It is a real danger that companies will stop developing vaccines altogether (Lam). Drug companies instead concentrate on well, drugs. Continuous treatment medications require patients to purchase repeatedly, until it is no longer necessary. (In some cases, patients may even take certain drugs until death.) The time interval of vaccinations is, at the very least, yearly. In the case of the flu, rather than one flu shot, pharmaceutical companies can profit more from selling antivirals, painkillers, and a host of other treatments to patients that contract viral sickness. Medications, rather than cures are economically desirable. As a biochemistry student myself, upon graduating I face the decision between conducting decent paying scientific research or developing pharmaceuticals with the opportunity of making upwards of $200,000 a year for