The Components Of Genetic And Environmental Conditions

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle Cell Anemia affects many people all over the world; Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. When a person is diagnosed with sickle cell anemia the blood cells start to become clogged blood vessels, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.

In this article, sickle cell anemia is defined as a hereditary disease that destroys red blood cells by causing them take on an elongated and rigid "sickle" shape. In addition, a different type of hemoglobin called Hemoglobin S, is the protein in red blood cells that carry oxygen throughout the body. This protein starts to wrap around other red blood cells when oxygen is lacking to form a helical shape. Once this happens the cells cluster together and elongate and the cells start to "sickle". A person who has sickle cell anemia can only get it if both of their parents carry the sickle cell trait, if only one parent has the trait then there children are at risk for having the trait.

Approximately 100,000 people suffer from Sickle Cell Anemia everyday and about 2 million people have the Sickle Cell trait in the United States alone. Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Pruthi 2018). The disease is estimated to occur in 1 in 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans (Pruthi 2018). Sickle cell anemia is an inherited form of anemia, a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout your body normally, your red blood cells are flexible and round, moving easily through your blood vessels. In sickle cell anemia, the red blood cells become

Sickle cell anemia is a blood disorder that happen very commonly in the African descent.

Sickle cell disease is categorized as an autosomal recessive disease. That means in order for one to inherit the disease, they must inherit two recessive alleles for sickle cell disease, or hemoglobin S gene. Having only one recessive allele makes you a carrier. The disorder causes the affected person’s red blood cells to disfigure into a crescent or sickle, which differs from the normal red blood cells that shaped into a doughnut. Sometimes, cells in a sickle shape cannot get through the narrow passageways of the blood vessels as easily as normal red blood cells. This blocks blood from entering and oxygen can’t reach the affected person’s organs. It can also crystallize and block arteries and

Sickle cell disease is a hereditary blood disorder caused by an abnormal hemoglobin in the red blood cell. Hemoglobin is a type of protein that carries oxygen in the body. In order for someone to have sickle cell disease they would need to have been passed down from at each one of their parents, by inheriting a total of two hemoglobin genes. The fact that this is a hereditary disease means that it is not considered to be contagious. This disease comes in about six different forms, but the most severe of them all is sickle cell anemia. Sickle cell is an inherited disease that affects the red blood cells causing debilitating symptoms, however, with treatment people with this disease can quite possibly live an otherwise

So what exactly is Sickle Cell Anemia? Sickle cell is an inherited blood disorder that affects red blood cells due to the presence of an abnormal form of hemoglobin, namely hemoglobin S. Sickle cell has a lot to do with natural selection and is known as genetic disorder. You may never know who will have it in your family. It will not affect everybody. Sickle cell effect the red blood cells in your body. The red blood cells in your body begin to become deformed. They begin to look, “crescent shaped and have difficulty passing through small blood vessels, which could slow or block blood flow and oxygen to parts of the body.” The cresset shaped is where sickle cell gets its name from. When sickle cell mutates in your body, it begins to effect the muscles and even could possible effect the oxygen flow into your body. When the oxygen is blocked, this causes pain and even harm to your organs and even muscles. When this happen, this effects a person ability to be active. According to web MD, “Severe pain is an emergency called acute sickle cell crisis. A person may not know what brought on the pain, but infection and dehydration are common triggers.”

Sickle cell anaemia is a disorder affecting the red blood cells and up to 100,000 people are estimated to have the disease in the USA (Centre for Disease Control). Due to a genetic mutation in the gene responsible for the production of haemoglobin (MayoClinic, 2014) the red blood cells, which are usually a biconcave disk in shape, become sickle (bent) shaped (Figure 1) and the haemoglobin that the red blood cells contain is defective. Haemoglobin is a protein that carries oxygen (which has bind to the haemoglobin) around the body from the lungs after gas exchange. Having defective haemoglobin, as is the case with sickle cell anaemia, means

The cause of sickle cell anemia is by a mutation gene. The gene tells your body to make hemoglobin. Hemoglobin is responsible for giving the blood its red color and allows the red blood cells to carry oxygen from your lungs to all the parts of your body. The sickle cell gene is passed down from one generation to the next and is inherited. It is called autosomal recessive inheritance. This happens when both the mother and father pass on the detective form of gene. If only one parent passes on the sickle cell gene to the child that means the child will have the sickle cell trait. People who have the sickle cell trait are carriers and can pass the defective gene to their children. Your ethnic background can put you at risk for sickle cell anemia.

Sickle cell anemia is an inherited disease causing red blood cells to malfunction. It is a disorder the affects hemoglobin the protein found in red blood cells. People with this disease genetically inherit this untypical hemoglobin. This means that it cannot be transmitted from one person to another like the flu virus. These people have what its called hemoglobin (s). What this does is that instead of the red blood cell being circle-shaped it would appear to be a half moon shaped cell. It is necessary for the cells to be round so that they would be able to pass though small and large blood vessels.

Sickle cell disease is a blood disorder in which red blood cells take on an abnormal shape. Sickle cell anemia is when the red blood cells hemolyze, or die. Sickle cell disease is inherited from generation to generation and is the most common in inherited blood disorders. An estimated 70,000-100,000 people in America are currently suffering from this disease, most of which are African Americans. One is diagnosed with sickle cell disease in early childhood generally around four months old when the signs and symptoms are presented. Because of its huge impact, the United States requires all newborns to be tested for this disease. [1] Sickle cell disease is known to affect, “approximately 1 in every 400-500 African American

Sickle cell disease is a chronic condition that a person can inherit from their parents in which it effects the globular structure of the patients red blood cells. A more sickle shaped structure, which can alter a person’s blood flow, replaces the more common globular structure. This impairment in blood flow can lead to blood clots, severe debilitating pain and damage to vital organs such as the liver, kidney and spleen. This disease currently affects over 90,000 people in the United States, with the majority of them being African American and

Sickle cell anemia affects millions of people worldwide. Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. They don't last as long as normal, round red blood cells, which leads to anemia. Sickle cells contain abnormal hemoglobin that causes the cells to have a sickle shape. Sickle-shaped cells don’t move easily through your blood vessels. They’re stiff and sticky and tend to form clumps and get stuck in the blood vessels. The sickle cells also get stuck in blood vessels, blocking blood flow. This can cause pain and organ damage. Sickle cell disease is caused by a mutation in the

First of all what is sickle anemia? It’s a disorder that is affects your blood cells and hemoglobin which is a molecule that is in your red blood cells that delivers oxygen to the cells and throughout your entire body. When people realise that they have sickle cell is when they have the following symptoms, chest pain problems and difficulty breathing, strokes, joint pain, arthritis and severe infections. People are diagnosed with sickle anemia at a very young age people get from their parents if both parents have a genetic gene of sickle then, more likely their offspring will have the disease it 's a very popular and common disease it affects millions of people worldwide the most common type of people who do get sickle cell anemia more than any other is African Americans because the disease is mostly in Africa and the Mediterranean countries such as Greece, Turkey, and Italy. In the United States the diseases affects more than, 70,000 to 80,000 american people and 1 and 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans have the disease already inside of their body what type of gene is making them have sickle cell that would the HBB gene is what causes sickle cell anemia. Why is it called sickle cell anemia because the hemoglobin is shape like a ‘S’ shape or it can be called a sickle instead of a normal round red cell some scientists think that the disease might be with the deadly disease of malaria because since it is common in Africa when the people

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. A person that is diagnosed with sickle cell anemia, their blood cells start to become clogged, causing blood clots, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.