The Development of Antibiotic Resistance

Bacteria are not just all of a sudden becoming resistant to antibiotics they have always had a bit of resilence, as a human species we have always developed something it doesn’t work we will develop something stronger, that has been the downfall in this instance. Pencillan is a great example as it is one of the most highly used antibiotic and is derived and made from mold.

Antibiotic resistance evolves in bacteria. Charles Darwin created the theory of evolution which focused on natural selection being the key factor of how things change. Natural selection is when organisms that are better suited to the environment are able to reproduce successfully. Evolution is descent with modification. Bacteria can become resistant to antibiotics by a mutation. The bacteria that did not die from the antibiotic inherited the gene from an ancestor that made it resistant. Since the other bacteria is dying faster than the resistant bacteria, the resistant bacteria are able to multiply

Antibiotic resistance is when microorganisms, such as bacteria, are able to survive an exposure to antibiotics and these bacteria are now resistant to the effects of these antibiotics. Antibiotic resistance in bacteria has been an issue since antibiotics were discovered. The fact that bacteria can become resistant to our medical treatments such as antibiotics is a natural evolutionary process, but there are certain human contributions that definitely speed up the process. For example, one of the main contributions that will be discussed is the problem of over prescription of the antibiotic drugs. The

Antibiotic resistance happens when bacteria come into contact with an antibiotic over and over again.

The overconsumption of antibiotics is a big contribution to drug resistance and is why users should know what happens with the repeated use of these drugs. Even though some bacterial mutation occurs naturally, human use of antibacterial is the cause of higher-levels of resistance (Alliance for the Prudent Use of Antibiotics 2014). Bacteria mutate either by genetic mutation or by receiving the defensive agent. During an infection bacteria multiply naturally within the body and when exposed to antibiotics, bacteria have an opportunity to adapt to the drug (Alliance for the Prudent Use of Antibiotics 2014). During this period of

The research questions to understand are: How do bacteria become resistant to antibiotics? What is the history of antibiotics and the emergence of antibiotic resistance? Why are bacteria becoming resistant to antibiotics?

Like any other organism, bacterium are subject to evolutionary pressure. Antibiotic resistance in bacteria is rarely the result of a single mutation leading to full resistance, but rather the result of a series of mutations that incrementally increased antibiotic resistance. For example, in the case of fluoroquinolone resistance, resistance started with a mutation in the efflux pump, granting Streptococcus pneumoniae the ability to survive certain treatment regimens (13). This became an issue when people started to misuse their antibiotics. In this particular example, because patients did not follow their prescription regimens, they only killed the bacteria not resistant to fluoroquinolone. This selective pressure drove bacteria to further develop fluoroquinolone resistance, meaning that the initial infection remained untreated, and would now require a

Studies show that twenty-three thousand out of two million with infection dies because antibiotic resistance(Center for Disease Control). What exactly is antibiotic resistance and how did bacterias become resistant

Mutations and genetic evolutions in the bacteria are two ways resistance is growing. These mutations and genetic evolutions get passed down to the next generation, which makes it difficult for scientists to create antibiotics that work each specific strain of bacteria ("Facts about Antibiotic Resistance" 2016). Many resistant antibiotics have targeted the cells by inhibiting the enzymes that usually stop the spread of the bacteria (Diekema 2016). Scientists need to look into preventing these enzymes from getting blocked so the antibiotics can stop the replicating

Today, the use of antibiotics is very common. The gene that causes antibiotic resistance typically arises naturally or from a mutation. When bacteria are exposed to antibiotics, the bacteria with antibiotic resistance genes within the plasmid survive; this is called selective advantage. This process of the survival of bacteria that are resistant to antibiotics is a method of natural selection, causing more antibiotic resistant bacteria to be reproduced. They are rapidly reproduced by binary fission, conjugation, transformation,

In this paper, I address some major ethical issues associated with the ineffective use of Antibiotics which contributes to Antimicrobial resistance (AMR), as Antimicrobial resistance is a direct consequence of not considering several bioethical factors associated with proper use of antibiotics since its advent. The Antimicrobial resistance is a result of ceaseless selection pressure over bacterial population during several generations from human application of antibiotics through overuse, underuse and misuse. In the first section, I have discussed why AMR currently has become one of the major public health concerns and the impacts of the AMR on global public health should not merely be viewed as a technical or medical problem but as a distinct

Bacteria is able to become resistant to antibiotics meaning when characteristics are ‘favourable’ within a population e.g. resistance to antibiotics, through evolution by natural selection the ‘favourable’ characteristic is passed on to the next generation. This is a problem as the effectiveness of antibiotics is quickly reduced as the population grows. There are organisms known as superbugs which are resistant to almost all antibiotics that are available

According to Cable News Network, reported that, “the Center for Disease Control is categorizing antibiotic-resistant organisms by threat level. That’s because, they have estimated, more than 2 million people get antibiotic- resistant infections each year, and at least 23,000 died because current drugs no longer stop their infections” (Falco,1). Antibiotic-resistance is becoming a growing issue in society today. “A 59-year-old man was hospitalized with Klebsiella pneumonia strain, and was treated with multiple antibiotics, including the most powerful antibiotic there is. The overuse of antibiotics caused his body to become resistant to the drugs” (McKenna,3). Antibiotic resistance occurs when bacteria change in a

Antibiotic resistance happens when bacteria come into contact with an antibiotic over and over again. Over time, the bacteria

“Each antibiotic operates at a specific site within the bacterial cell”, as stated by Khachatourians, “thus, when resistant organisms arise, their resistance is specific to particular antibiotics”.