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The Effectiveness And Side Effect Possibilities Of The Combined Treatment For Type 2 Diabetes Mellitus Essay

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Assessment of the effectiveness and side-effect possibilities of the combined treatment for type-2 diabetes mellitus

Diabetes mellitus (DM) is a chronic metabolic disease which is mainly caused by the abnormalities of insulin regulation to control glucose level in the blood, thus resulting hyperglycemia [1, 2]. There are currently two major distinct types of DM, namely type-1 and type-2 diabetes. Type-1 diabetes corresponds with the inability of pancreatic hormonal glands to produce sufficient insulin to effectively regulate blood-sugar level, therefore called insulin-dependent diabetes. On the other hand, patients with type-2 diabetes are not suffered from insulin deficiency but instead, the inability of their body to fully utilise the produced insulin, hence non-insulin-dependent diabetes [1, 2].
Among the two types of DM, type-2 diabetes has been reportedly attributed for a major part of the global diabetes patient population [1]. In 2014, the world’s diabetes population has reached 422 million, an almost four-times increase than 1980 [1]. Type-2 diabetes has also been accounted as a major death cause. According to the WHO [1], it is estimated that one and a half million of people were dead due to the direct impacts of diabetes in 2012 and another two million deaths were related to higher blood-glucose level.
The symptoms of these two types of diabetes are similar [1], e.g. excessive thirst, frequent urination, weight loss, and deteriorating eyesight [2]. Nevertheless,

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