The Effectiveness Of Cymbalta On Major Depressive Disorder

The medical article talks about researchers on the topic on depression. States that depression affects one in six people in America which approximates to about 17. 6 million people each year. Patients suffering from depression are at high risk of developing cardiovascular disease type 2 diabetes. People suffering from depression have also shown suicidal ideation as seen in the Canadian study which 485 of the patients showed the signs.

Cymbalta (Duloxetine) is a Serotonin Norepinephrine Reuptake Inhibitor (SNRI) use to treat depression (Breggin, 2013). There are several therapeutic and biological alternatives being implemented to control hopelessness. Many researcher are recommending other types of treatments before psychotropic therapy is implemented (O 'Mathuna & Larimore, 2010). Some of the therapeutic alternatives are Reflexology, Craniosacral Therapy (CST), Acupuncture, Exercise, Meditation and Direct Amino Acid Therapy Maintenance (Keegan, 2001). St John’s Wort, Passionflower, Valerian and Omega 3 fatty acids are a few of the biological options available to combat depression (Keegan, 2001). The dietary supplements tryptophan and

Major depressive disorder is one of the most common mental disorders, with a 12-month prevalence of 6.7% of adults in the United States (NIMH). There is no definite etiology of depression, but several risk factors have been identified. Functional and structural changes in the brain have also been explored. The most common treatment for depression is the use of drugs that act on monoamine transmitters, including norepinephrine, dopamine, and serotonin. Decreases in these transmitters, especially serotonin, were hypothesized to play an important role in the cause of depression (Breedlove & Watson, 2013). The serotonin hypothesis led to the development of selective-serotonin reuptake inhibitors (SSRIs), which increase the amount of serotonin in the brain. Further research suggests that the serotonin hypothesis is not entirely accurate and the neurobiology of depression is much more complex. The “chemical imbalance” explanation of depression may not reflect the full range of causes and may be given greater credibility by patients and doctors than is supported by evidence based research.

Major depressive disorder, we all have probably heard of it, but do we really know what is it is ? Major depressive disorder is “a mood disorder that causes a persistent feeling of sadness and loss of interest… major depressive disorder or clinical depression, affects how you feel, think and behave and can lead to a variety of emotional and physical problems”(Mayo Clinic Staff). Having this disorder puts you in a very unstable position because you are constantly feeling depressed so it affects the way you think and feel and that can be very dangerous. Sometimes this happens to a person for one day, but put yourself in the shoes of someone who experiencing this for more than two weeks? When you have major depressive disorder, the signs of depression disorder can last for two weeks or more(myers646). This dis order must be treated immediately because “depression may make you feel as if life isn 't worth living”(Mayo Clinic Staff). Feeling this way can lead you to doing things that you can not take back such as committing suicide and sadly that can happen when you have major depressive disorder. Kiyohara and Yoshimasu conducted a research that showed that 90% of suicides have were dealing with major depressive disorder(qtd. in The World Health Organization). Throughout this paper I will be discussing the causes, symptoms and treatment when dealing with major depressive disorder.

Mental disorders can be diagnosed in infancy, childhood, or adolescence. Major depression is a lost of interest or pleasure in all activities. People with major depression experience symptoms such as a change of appetite, restlessness sleep, decreased energy, feeling of worthlessness, difficulty concentrating, and/or suicidal thoughts. A major depressive episode can lasts for about 2 weeks or more. A major depressive episode can be caused by stress, social anxiety, or other reasons. People with a milder depression are able to function and seem normal (DSM-IV-TR). A major depressive disorder affects about 14.8 million adults in America with 6.7 million at age 18 and older in the United States population. A depressive disorder can develop in any age and more likely to occur more often in women than in men and any person who is going through a hard time can develop depression. A treatment for individuals with depression is medication, psychotherapy, or attending social groups, 80 percent of the people who follow up with these treatments begin to show improvement with in four to six weeks. About 50 percent of the patients that take medicine to “cure” the depression are unsuccessful with the treatment, because they stop taking their meds due to the side effects, but the people who are in the support

One of the most common psychiatric disorders is known as clinical depression and affects anywhere between 3% and 13% of the population with some form of depressive symptoms affecting as much as 20% of the adult population at some point in their lives (Amenson & Lewinson, 1981; Kessler et al., 1994; Oliver & Simmons, 1985, as cited in Antonuccio, Danton, & DeNelsky, p. 574). The concept of ‘harmful dysfunction’ advanced by Horwitz and Wakefield (2007) describes two key components of clinical depression: a dysfunctional mechanism and the dysfunction being harmful to the individual (as cited in, Parker & Paterson, p.405). This paper explores the following questions: what does research indicate about clinical depression and what are the implications for treatment? Reviews are presented in regards to the emergence of depression and psychotherapy versus medication to treat clinical depression. Considerations are briefly discussed and the research paper will conclude with an interpretation of the critical points.

The research critically analyses the desired effects of the depression and the antidepressants available for the depressions. Depression symptoms are commonly seen among people of various ages. There are some of the antidepressants that are initially recommended for overcoming the issues of depression. Some of the well-known methods have been used by many of the known researchers regarding the topic of depression. Proper evaluation of the research methodology about depressions will help in the better understanding of the mental state of the people suffering from the diseases of depression. The evaluation of the two of the research papers mentioned above highlights the fact that research between a certain numbers of the people will help to evaluate

Depression is a chemical imbalance of the brain, usually when the part of the brain that produces serotonin produces the chemical in lower quantities (Rivas). Every year Americans consume more anti-depressants than any other nation in the world and from the years “1988-1994, the use of anti-depressants increased by 400%” (Ross). Statistically speaking, women have a 70% chance of developing depression over men and about 13% of the women who have children would develop postpartum depression (Holms). There is no doubt that depression impacts a large amount of people and affects the wallets of those with depression. Globally, 350,000,000 people suffer from some form of depression, of those affected with depression; $80,000,000,000 is spent on antidepressants and therapy (Holms). There are

According to Barlow (2008), major depressive disorder (MDD) is the most common depressive disorder and affects million of Americans each year. The symptoms experienced by individuals with MDD can be debilitating. The Global Burden of Disease Study, initiated by the World Health Organization, estimated depression to be the fourth leading cause of disability in the world (Barlow, 2008). To further examine this, The National Comorbidity Survey Replication (NCS-R) found that each year roughly 13 million

The demand for antidepressants has skyrocketed since the early 1990’s with a majority of users being adults. Appalling to this fact is that about half of those under the prescriptions have in the recent past visited a mental health professional. In addition to this, almost 60 percent of those who use antidepressant do not really need them. I also concur with the fact that our modern lifestyle has contributed so much to augment depression rate.

Depression is often described in superficial terms based on the manifestation of symptoms but falling short of capturing the complexity existing within the intrinsic etiology of the disease. It is one of two classifications of mood disorders with the other being Bipolar Disorder which is also known as manic-depressive illness. Major depression is one of the most common mental disorders in the United States. The lifetime prevalence rate of depression is 16.2% of the population with a two-fold greater risk in women than men after adolescence (McCance, 2010). Signs and symptoms characteristic of Major Depression include sadness, irritability, significant weight gain or loss, insomnia, guilt, and suicide ideation. It is distinguishable from Bipolar Disorder in that it lacks symptoms of mania. Risk factors associated with depression are stress, comorbidities, life changes, and substance and/or alcohol abuse. It is important to understand the relative risk associated with these risk factors when determining treatment. For example, the relative risk between the substance abuse, depression, and suicide is evident in a recent analysis conducted by The National Survey on Drug Use and Health focusing on the suicidal thoughts and behavior among adults with substance dependence or abuse and adults with major depressive episode. Results indicated that adults 18 or older who had past year substance

Depression is a normal emotional reaction to perceived loss and hopelessness (Segal, Williams, & Teasdale, 2002). There are a number of different types of depression such as chronic depression, manic depression and the primary focus of this essay Major Depressive Disorder (MDD). MDD is a clinical depression, which is more chronic and more severe compared to other types of depression. It significantly disrupts the individual’s ability to meet the normal demands of life. According to many clinicians, clinical depression should be considered as a medical illness in need of medical intervention. Other mental health professionals believe this is an overstatement of the role of physiology and the

The first step to treating many of these new cases of depression is the prescription and use of antidepressant medication, however this has cause a mass flooding of our society with unnecessary prescription drugs. Due to the ease of treatment, primarily with prescription drugs, and the large range of severity in depression is often over diagnosed, adding to the problem.

The severity of depression has been supported through scientific evidence that indicates that depression has a biological basis in the brain of a depressed person along with psychological and social implications. Whilst there are many catalysts in a person’s life that can be identified as a possible root cause of depression, such as stressful life events or the death of a loved one, the issue is far more complex, as the biological triggers of depression are not as easily expressed, such as faulty mood regulation in the brain, vulnerable genetics in the DNA, and other medical problems. Many things are altered in the brain of the depressed person. Firstly, what most understand to be an imbalance in the levels of chemicals that regulate emotions, is in reality far more elaborate. The true issue surrounding the many chemicals involved inside and outside of the nerve cells that undergo numerous chemical reaction which make up the dynamic system that is responsible for mood, perceptions, and the way one experiences life you experiences life can be altered in different ways that affect how one lives. Along with the brains chemicals, the connections between nerve cells called neurons decrease and deteriorate, meaning the

Depression is the most common of all psychological disorders, affecting 100 million people worldwide. The depression ranges from mild feelings of uneasiness, sadness, and apathy to intense suicidal despair. (Kasschau) If left untreated, it could lead the