The Effects Of Hormone Therapies On Human Body And Will Further Explore Fatigue

1420 Words Aug 12th, 2015 6 Pages
Traditionally men are expected to be the stronger sex, the breadwinner, the hunter- gatherer, but when it comes to prostate cancer men can feel powerless. Hormone therapies are used to chemically castrate men as a means of treating the cancer through more personalised medicine. However, when the cancer becomes refractory, Docetaxel is used as a first line chemotherapy to treat metastatic castration resistant prostate cancer in combination with Prednisolone. Mr. Smith (pseudonym) was diagnosed with Advanced Metastatic Prostate Cancer which was controlled by Abiraterone Acetate (an androgen biosynthesis inhibitor and works by inhibiting the CYP17 enzyme that is used to feed the cancer) until the cancer started to progress, and was commenced on Docetaxel combined with Prednisolone. For this assignment I will closely examine Docetaxel’s mechanism of action on the human body and will further explore fatigue as one of the side effects most commonly experienced by patients receiving Docetaxel.
Young et al predicted back in 2006 that by 2015 there will be approximately 1.25million cancer deaths this year, however, according to the World Health Organisation there were 8.2million cancer related deaths in 2012 surpassing Young’s prediction. Prostate cancer is the most commonly diagnosed cancer amongst men, affecting one in four (CRUK, 2011). Barber et al (2008) have estimated that there are approximately 30,000 incidences of prostate cancer diagnosed each year in the UK including…

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