The Effects Of Sleep On Cognitive Function

1656 WordsSep 26, 20157 Pages
In the present study we sought to characterize abnormalities in sleep architecture and quality, in a cohort of patients with medically refractory versus and controlled epilepsy, versus normal healthy controls and to study the effect of sleep parameters on cognitive function in these groups. The main observations made were of significantly longer self-reported and polysomnographic TST in patients with refractory epilepsy in comparison to controlled epilepsy and healthy controls. Sleep architecture was also found to be markedly disturbed among epilepsy patients in both groups, with prolonged REM latencies, and frequent arousals and awakenings although these abnormalities were statistically similar between the groups. Our main observation is that higher total sleep time has a negative correlation with memory and executive function performance. Sleep parameters among patients with epilepsy: Pereira A et al in 2012,(Pereira et al., 2012) in 25 drug refractory epilepsy pediatric patients, reported that they had showed a decrease of total sleep time (TST), of N3, and of REM sleep and an increase in WASO and decreased sleep efficiency. A similar study involving 40 pediatric age group patients, reported that intractable epilepsy patients have longer sleep latency poor sleep efficiency along with higher arousal index as compared to medically controlled epilepsy (Kaleyias et al., 2008). In a previous study of ours(Zanzmera et al.,
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