The Epidemic Of Bovine Tuberculosis

Tuberculosis has long been a disease that the human culture has been dealing with which entails significant morbidity and mortality worldwide. With dealing with such a horrific disease over the years, discoveries and evolution on the appropriate ways to contain, diagnose, and challengingly treat the disease has changed. One of the most concerning complications of this worldwide public health issue is the ability for it to quickly spread in high populated areas while becoming ever more resistant to forms of treatment not available in all locations around the world. This is a serious public

TB is still proven to be a top killer around the world, and with more cases of drug resistant TB being reported daily, the cost of treating and preventing this disease will continue to be on the rise.

“Tuberculosis (TB), a multisystem disease with myriad presentations and manifestations, is the most common cause of infectious disease–related mortality worldwide. Although TB rates are decreasing in the United States, the disease is becoming more common in many parts of the world. In addition, the prevalence of drug-resistant TB is increasing worldwide. TB is caused by M tuberculosis, a slow-growing obligate aerobe and a facultative intracellular parasite. The organism grows in parallel groups called cords (as seen in the image below). It retains many

While tuberculosis was never completely eliminated, there was a significant drop in cases and death rates, as a result of the BCG vaccine and new anti-tubercular drugs in the 1950’s.

Tuberculosis is a deadly disease that is now affecting our world and the people living in it in a horrible way. Due to many factors such as poverty, HIV/AIDS, and lack of health care, many third world and developing countries have been left very vulnerable to tuberculosis. It is affecting a large part of these countries and is leading them deeper into poverty and sickness. The effort to help these countries against tuberculosis has only been slightly effective against this widespread and destructive disease.

Tuberculosis has been part of human history for a long time but how long is a long time? Recent research using genetic data has allowed us to know that the tuberculosis progenitor has been on this planet for about 3 million years affecting even our earlier ancestors (Gutierrez et al, 2005). Additionally this research showed that the bacilli from tuberculosis are capable of mixing sections of their genome with other strains and giving the pathogen a composite assembly, which resulted from ancient horizontal exchanges before its clonal expansion. This quality provided tuberculosis a big advantage that even now a days allows the organism to evade, adapt and create resistance to treatments that were once successful. In order to fix current and

Mycobacterium bovis not only causes bovine tuberculosis in badgers but also infects cattle and deer.

Tuberculosis is a disease of an infectious nature caused by a bacterium known as mycobacterium tuberculosis. The disease spreads through the air. People with the disease can spread it to susceptible people through coughing, sneezing, talking or spitting. It mainly affects the lungs and other parts such as the lymph nodes and kidneys can also be affected. The symptoms for TB are fatigue, coughing, night sweats, weight loss and fever. One third of the population of the world is affected with mycobacterium tuberculosis. The rate of infection is estimated to be one person per second. About 14 million people in the world are infected with active tuberculosis. Drug resistant TB has been recorded to be a serious public health hazard in many countries. Resistant strains have developed making it difficult to treat the disease. TB has caused millions of death mainly in people living with HIV/AIDS ADDIN EN.CITE Ginsberg19981447(Ginsberg, 1998)1447144717Ginsberg, Ann M.The Tuberculosis Epidemic: Scientific Challenges and OpportunitiesPublic Health Reports (1974-)Public Health Reports (1974-)128-13611321998Association of Schools of Public Health00333549http://www.jstor.org/stable/4598234( HYPERLINK l "_ENREF_3" o "Ginsberg, 1998 #1447" Ginsberg, 1998). The World Health Organization came up with the DOTS (Directly Observed, Therapy, Short course) strategy. The approach involves diagnosing cases and treating patients with drugs for about 6-8

Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover the increasing prevalence of HIV-AIDS and diabetes mellitus is being proved to be providing predisposition to tuberculosis. As witnessed by the WHO, which has estimated that, in the year 2012, 8.6 million people have developed tuberculosis and 1.3 million have died of the disease including 320000 deaths of HIV-TB co-infected people (Global tuberculosis report 2013. World Health Organization; 2013). Long term antibiotic therapy and that too associated with several side effects and discomforts have diminished patient compliance with the anti-tubercular chemotherapy. This fact in turn has raised the new deadlier MDR-TB and XDR-TB strains. The whole scenario is a matter of panic and questioning the effectiveness of anti-tubercular antibiotics, immunologic efficacy of century old BCG vaccine and all other medical advents.

Tuberculosis (TB) is brought on by a bacterium called Mycobacterium tuberculosis. The microorganisms more often than not assault the lungs, however TB microbes can assault any part of the body, for example, the kidney, spine, and mind. Not everybody infected with TB microbes gets to be sick. Therefore, two TB-related conditions exist: latent TB infection (LTBI) and TB infection. If not treated legitimately, TB can be deadly (CDC, 2016). TB microbes are spread through the air starting with one individual then onto the next. The TB microorganisms are put into the air when someone with TB illness of the lungs or throat coughs, talks, or sings. Individuals adjacent may take in these microscopic organisms and also become ill (CDC, 2016). Individuals with TB are well on the way to spreading it to individuals they invest time with consistently. This incorporates relatives, companions, and coworkers or classmates.

Canada has had many events where tuberculosis was having an outbreak in 1924 through 1948, but since then it has been decreasing. We have dealt with this problem back in 2012 where an outbreak of tuberculosis infected 8% of the individuals in the extremely small Northern Quebec community of Kangiqsualujjuaq. After the outbreak The Public Health Agency of Canada is running over to discover the origin of the outburst its spread. Officials are also bringing up more additional resources to the place, such as a mobile x-ray machine. Tuberculosis is a disease caused by bacteria that travel from person to person. A person who is infected with tuberculosis, but does not show any symptoms at all may have dormant tuberculosis and can still transmit

According to the World Health Organization, tuberculosis (TB) is the number two killer worldwide due to a single infectious agent (WHO, 2017). In 2015, 10.4 million new cases have been identified and 1.8 million people have died from this disease (WHO, 2017). TB is caused by the bacteria Mycobacterium TB, and the majority of TB deaths occur in low and middle-income countries. This disease is curable and preventable, but the lack of access to proper healthcare and medication administration makes it a concern for the most of the world’s population. TB is an airborne disease that can transmit when an infected person coughs, sneezes, spits, laughs, or talks. The majority of TB cases can be cured when the right medications are available and

(Tortora, Funke & Case, 2013). Another mycobacterial species, Mycobacterium bovis, is a pathogen mainly of cattle. M.bovis is the cause of bovine tuberculosis, which is transmitted to humans via contaminated milk or food (Tortora, Funke & Case, 2013). It is very unlikely to see M. bovis transmitted from person to person. It will impinge bones causing a hunchback deformation of the spine; it also will affect the lymphatic system. In the latent stage, the patient is asymptomatic due to TB is inactive. Symptoms may appear weeks or even years later after acquiring the infection. In the active stage symptoms will include a cough that may last three weeks or more, expectorating blood, erratic weight loss, more tiredness than usual, fever, Night sweats and chills. Active TB is indicative to the spread of the infection; which happens when the bacteria advances from person to person from unhindered microscopic droplets dispensed into the air. Two of the most-common test used to the diagnosis tuberculosis is a simple skin test and chest x-ray. The skin test is done by injecting a minute amount of PPD under a patient's skin creating a welt on the forearm. The results are read in 48-72 hours by a health professional; they will check for swelling at injection site. If the PPD test reads false positive then, a chest x-ray will be ordered. Chest x-rays are

Tuberculosis is among the fatal diseases that are spread through the air. It’s contagious, meaning that it spreads from one infected individual to another, and at times it spreads very fast. In addition to being contagious, the disease is an opportunist infection as it takes advantage of those with weak defense mechanism, and especially the ones with terminal diseases like HIV and AIDS. Tuberculosis is therefore among the major concerns for the World Health Organization due to its contagious nature (World Health Organization 1).

India, the second most populous country with over 1.31 billion people, has the highest burden of tuberculosis (TB) in the world, accounting for 20% of the global incidence of TB, and an even higher share of global incidence of multi–drug resistant (MDR) TB. With an estimated 2 million new cases of TB and 5, 00,000 TB-related deaths in India annually, those who got diagnosed with different forms of DR-TB were 35,385 cases but only 20,753 people started on multidrug-resistant TB (MDR-TB) treatment in 2013. The National Tuberculosis Program was launched in 1962, but suffered heavily continuing TB led mortality. Acknowledging this reality, a Revised National Tuberculosis Control Programme (RNTCP) was launched by the Government of India in 1997, however even today it does not comply with World Health Organization (WHO) recommendations.