The Ethics of Xenotransplantation Xenotranplantation is the controversial procedure that involves

1100 WordsApr 23, 20195 Pages
The Ethics of Xenotransplantation Xenotranplantation is the controversial procedure that involves the transplantation of an animal's live cells, tissues, body fluids, or organs 1. Define Canada's position on xenotransplantation Due to fewer deaths caused by car crashes and gunshots, Canada lacks in its number of organ donors. Hoping for development in the xenotransplantation is our only hope at this point. Although Canada is encouraged to participate in further research regarding the xenotransplantation, alternatives to this must also be looked into. The alternatives vary from further stem cell research, and ways to increase to organ donors. 2. Research to determine if/ where research on transplantation is being carried out In Canada,…show more content…
This results in endothelial damage, inflammation, thrombosis and necrosis of the transplant. Acute vascular rejection (xenoactive rejection) occurs in 2-3 days if hyper acute rejection is prevented. This is much more complex and not understood. To prevent this, the use of immunosuppressive drugs is necessary. Cellular rejection: due to the response of the immune system, since the response is elicited by XNAs. mediated by: • Natural killer cells, which accumulate in and damage the xenograft; and • T-lymphocytes, which are activated by MHC molecules through both direct and indirect xeno recognition. Chronic rejection: slow and progressive, and usually occurs in transplants that survive the initial rejection phases. Scientists are still unclear about the process, and research in this area is very difficult as xenografts rarely survive past the initial acute rejection phases. Xenozoonosis: transmission of infectious agents between species. Animal to human infection is normally rare, but has occurred in the past. An example of such is the avian influenza, when an influenza A virus was passed from birds to humans Reasons are: Implantation breaches the physical barrier that normally helps to prevent disease transmission, The recipient of the transplant's immune system

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