The Field Of Cosmetics And The Treatment Of Injuries, Skin, And Hair

What impact does the illness have on the blood’s ability to clot? Include the role of vitamin K and the specific clotting proteins affected. Also discuss platelet production. Describe the test that is typically run to test the blood’s clotting ability.

In Cardone presentation, His main focus was on Platelet-rich plasma (PRP), (plasmas that come from the patient’s body, and is centrifuged to increase the concentration of platelets combined with remaining blood). He also discussed the potential advantages as well as potential drawbacks and uncertainties regarding the use of PRP injections to treat

- Coagulation inhibitors and Fibrinolysis : to Localize thrombus on injury and Prevent new thrombus formation.

Platelets are not really cells in a way. As Marieb (2012) mentions,” They are fragments of bizarre multinucleate cells called megakaryocytes (meg″ah-kar′e-o-sītz), which pinch off thousands of anucleate platelet “pieces” that quickly seal themselves off from the surrounding fluids” (p. 344) The liver helps produce blood clotting factors. If it is not in working order then the person is not able to stop bleeding as easily as someone who has a properly working liver. There is a correction to help produce the proper amount of blood clotting factors and that is to take Vitamin K.

October 17, 2009, my world changed. My little brother, Brennan, was diagnosed with idiopathic thrombocytopenia purpura, in short known as ITP. Normally, platelets are made in bone marrow and make their way through the blood stream and filtered out by the spleen. In Brennan’s case, his platelets are destroyed by his body causing his platelet count to drop to life threatening levels. Brennan’s platelet count from 2009, to today in 2016, has never gotten higher than 20,000; which means that he is at risk for spontaneous bleeding at any time. Due to this, Brennan is not allowed to participate in sports and many other physical activities.

Although vitamin K along with FFP administration (often 15mL/kg), is currently considered the standard of care for reversal of VKAs, PCC offers an advantageous alternative. PCC is a derivative of fresh frozen plasma (FFP) that contains concentrated inactivated factors II, VII, IX, X, protein C and protein S. Clinically, there are two types of PCC available: three factor (3F-PCC) and four factor (4F-PCC), which are classified by the amount of factor VII the product contains.1 Every brand of PCC contains different concentrations of each clotting factor and antithrombotic components. For example one brand, Octaplex, contains; FII 11-38IU/ml, FVII 9-24IU/kg, FIX 25 IU/ml, FX 18-30IU/kg, protein C 7-31IU/ml, protein S 7-32IU/ml.5

People with ITP often have platelet counts below 20,000. As the number of platelets decreases, your risk of bleeding increases. The greatest risk is when your platelet count falls very low -- below 10,000 platelets per microliter. At this point, internal bleeding may occur despite a lack of any injury.

The normal platet count is 150,000 to 200,000, but when i was hospitalized my platelet count was at a signicantly low level of 3,000.

You might have heard about PRP but never really understood exactly what it’s for. PRP stands for plasma-rich platelet. The plasma is enriched with platelet consisting about three to eight times higher concentration than the normal level of platelet. PRP contains various growth hormones that helps stimulate the healing structure of both soft and hard tissues.

For this experiment, whole bovine blood was used. The first process was to separate the blood into cellular and plasma fractions. 100 µL of whole bovine blood was transferred into a yellow microcentrifuge tube that was labeled WB using a P-200. 50 µL of whole blood was added to a blue microcentrifuge tube labeled WB. Both tubes were capped and placed in ice. 2 mL of the remaining blood was transferred into a Clear 2 mL tube using a P-2000 and centrifuged for 5 minutes at 8000 RPM. Afterward, 800 µL of the supernatant from the Clear tube was transferred into a yellow tube labeled WP and 50 µL of the supernatant was added to a blue tube labeled WP. These tubes were then capped and kept on ice.

Rotational Thromboelastometry (ROTEM, TEM Innovations GmbH, Munich, Germany) and thromboelastography (TEG, Haemoscope, Braintree, MA) are whole blood coagulation analyzers that measure viscoelastic changes of the entire clotting process. Compared to the prothrombin time (PT/INR) and partial thromboplastin time (aPTT), which measure coagulation factor function, TEG/ROTEM can evaluate platelet function, clot strength, and fibrinolysis, (de Laz, Nascimento, & Rizoli, 2013). This additional information can help guide resuscitation efforts by classifying bleeding due to coagulopathy. As a result, the need for platelets, cryoprecipitate (fibrinogen, Factor VIII, von Willebrand factor, &

Platelet-rich plasma (PRP) is a patient’s own concentrated platelets. PRP contains a large number growth factors. These growth factors stimulate healing.

Platelets are small fragments of cells. Platelets process coagulation. This is done by them gathering at the site of an injury and in turn sticking to the lining of the injured blood vessel. This is a platform on which blood coagulations occur, resulting in the formation of a fibrin clot. This covers the wound and prevents blood from leaking out. Fibrin also forms the initial building blocks from which new tissue are formed, in- turn promoting the healing process. If there is an imbalance, for example to high of a number of platelets may result in clotting not necessary in the body that can lead to health risks or a lower than normal counts can lead to extensive bleeding. So they protect us by clotting and aiding in healing by producing

Cosmetics, first used in Ancient Rome for ritual purposes, were part of daily life for women, especially prostitutes and the wealthy. Cosmetics were applied in private, usually in a small room where men did not enter. Cosmetae, female slaves that adorned their mistresses, were especially praised for their skills. They would beautify their mistresses with cultus, the Latin word encompassing makeup, perfume and jewelry.

Cosmetics are substances that are applied onto the body and/or face to enhance a person’s looks or scent. Cosmetics can be make-up which is mostly used by women and it is to enhance a female’s appearance. It is normally applied to face, hair, and body. Cosmetics has been used throughout society since Ancient times. In Ancient Egypt, cosmetic chemistry was being used before anyone knew it related to chemistry. Cosmetics was being used for many reasons in Ancient times. It is said that Cleopatra bathed in donkey milk to keep skin smooth, this is an example to show that chemistry is being used for the benefit of skin care. Skin care is another example of cosmetic chemistry being used. Skin care has been an important factor in society. Skin care has been around since 3000 BC in Ancient Egypt. This was prepared by natural materials.