The Fight For Erectile Dysfunction Medicines

Many doctors, pharmacists, biochemists and scientific researchers have engaged tremendous efforts to providing drugs and supplements that would help overcome sexual malfunction and ill-health.

What are the most relevant dimensions along which to segment the patient market for ED treatment? Of the segments identified, which would you target initially with Cialis?

Sildenafil citrate is one of the drugs of choice for the treatment of erectile dysfunction. It is a selective inhibitor of cGMP-PDE5 or the cyclic guanosine monophosphate-specific phosphodiesterase type 5. Since erectile dysfunction or impotence is estimated to affect more than 140 million men around the world, many tend to resort to medications such as this drug. More than half of these affected men have physical or medical issues that lead to their impotence such as diabetes, and urological, neurological and circulatory conditions.

What makes the difference between Cialis and the opposite two erectile-disfunction medications, is the fact that this one persists in the physique for an extended period of time, bettering or enabling the physical potence to have intercourse for 36 hours or more Cialis used to be regarded to be more performant from this point of view. As the opposite two medications are prescribed to be taken for approximately an hour before the sexual act, Cialis does now not supply a time, but a surgeon should be assisted as stories show that there have been guys who've carried out the sexual act for half of an hour.After all it's not a good suggestion to make use of it more than once on a daily basis.

Similar to sildenafil, tadalafil may be prescribed for treatment of erectile dysfunction (ED). Tadalafil is marketed as Cialis for ED, and as Adcirca for PAH. Adcirca is prescribed as a 40mg dose (taken as two, 20mg tablets) by mouth, every day in the treatment of PAH. Patient compliance may be better with tadalafil compared to sildenafil since oral dosing frequency is 1x daily vs. 3x daily respectively due to Tadalafil’s longer half-life. As a PDE-5 inhibitor, Adcirca has similar ocular side effects to sildenafil including cyanopsia, chromatopsia, and blurred vision. Non-AION has also been reported in some patients taking Adcirca, though these patients had predisposing risk factors including a smaller disc, age > 50 years old, diabetes, hypertension, and smoking. However, a direct link between PDE-5 inhibitor use and Non-AION has not been found. Patients meeting this patient profile should be informed of their increased risk of developing NAION if using a PDE-5 inhibitor (“Adcirca (Tadalafil)-Uses, Dosage, Side

Relationships are important to people, no matter what else is going on. Despite relationships being important, more and more men are losing their jobs due to the recession. After a while, they are also losing their insurance or having their plans downgraded to something that covers less. When a man is dealing with something like erectile dysfunction it can be extremely hard to see all of these problems going on. Luckily, there is a plan of action that men who are suffering from this problem can take. If your insurance plan does not cover a drug such as Cialis, you can find out how to buy Cialis online!

The procedure explains letters containing surveys were mailed to eligible patients from the university hospital of urology, and affiliated primary care clinics to participate. From all the eligible participants for the survey, only one hundred and twenty four responded. From those that responded, the results show that more than eighty percent have seen improvement in erectile function. About thirty percent reported that their relationships with their partners have improved. Finally, about forty percent of the participants that Viagra has improved their lives overall. This study proves that Viagra has the potential to improve quality of life. Overall improvements as a result of using sildenafil have been

History: Viagra also known as sildenafil citrate was originally synthesized at Pfizer headquarters in Sandwich, Kent, England by a group of pharmaceutical chemists in 1989. The two people who are attributed with creating sildenafil citrate, and who were consequently the most important in doing research and development on the drug were chemists Peter Dunn and Albert Wood. They originally composed this drug, sildenafil citrate, to help treat angina and high blood pressure, two symptoms that are usually indicative of coronary heart disease. The drug is classified as UK-92480. Later, in 1991, when the drug is patented by Dr. Nicholas Terrett, who is also referred to as “the father of Viagra”, sildenafil citrate received its modern name, Viagra. A few years afterward, in the early 1990s, Pfizer compiles several early test in order to prove Viagra’s capabilities in reducing angina and treating high blood pressure. These trials, however, prove that Viagra is not effective at treating this symptoms at all, although the trial patients were reporting ongoing erections after consuming Viagra. This got Pfizer thinking, and in March of 1998, Pfizer re-patents Viagra and the FDA approves it, and instead markets it as a drug to help people who are suffering from erectile dysfunction (ED), and this time Pfizer has research to back their claim. In the first year alone, over 40,000 prescriptions were written

Cialis, the trademark drug of Lilly Icos can also be helpful to human beings in ways instead of curing erectile dysfunction. Clinical researches have learned that tadalafil, the most important component of Cialis can aid humans in lowering their blood stress, preserve a wellknown prostrate underneath manage and maintain an impending lung disorder. These further advantages of Cialis have made the future of Lilly Icos brighter.

close to 10 percent of male in the U.S. Each year gets plagued by erectile dysfunction, or impotence. Impotence or Erectile dysfunction is most commonly understood because the lack of ability to have or hold an erection that's ample for sexual endeavor. There has been a massive number of guys ingesting frequent Cialis as a medical healing for their impotence. Regularly occurring Cialis is consumed orally and has swiftly become some of the prescribed medicines. Urologists and non-urology authorities most likely supply this treatment to their sufferers for the treatment of erectile dysfunction. General Cialis is the first oral treatment that has been clinically established and validated to boost the high-quality of erections. Medical practitioners

Sildenafil, or more commonly known as VIAGRA, is a medication that is geared towards adult men with erectile dysfunction, abbreviated ED (Medicines - EMC). It is stated that about 30 million men in the United States suffer from ED (Viagra). In Viagra commercials and advertisements, blunt diction is utilized to highlight the common insecurities of men, which creates this idea that in order to fulfill one’s manliness, then an individual would have to take Viagra. In this particular advertisement, I noticed key ploys to entice a man suffering from ED to take Viagra as a means by using a bold selection of diction, a paradise getaway background seen from a cabana, and an inviting, seductive woman.

Cialis should be positioned as a ‘Game-Changer,’ and not so much as a competitor. While the two drugs share the common goal of treating ED, they accomplish it in a much different manner and Cialis should be touted as an upgrade from the first drug of its kind to enter the market in Viagra.

Opportunities-- Cialis has a very large target market that they could choose from can focus on the dropouts or the customers who were not completely satisfied with Viagra

PDE5, an enzyme found primarily in the smooth muscle of the corpus cavernosum, selectively cleaves and degrades cGMP to 5′-GMP. PDE5 inhibitors are similar in structure to cGMP and they competitively bind to PDE5 and inhibit cGMP hydrolysis, thus enhancing the effects of NO, resulting in prolonging an erection.

-The probability doctors will switch from prescribing Viagra, which has first mover advantages and is already considered a reasonable solution to ED, to prescribing Cialis.