The Four Families of the Filovirus Ebola

Ebola is classified as a type of viral hemorrhagic fever, filivirus. The natural host for Ebola is still yet to be defined, but in most cases of a viral hemorrhagic fever, arthropods and rodents, such as ticks and mosquitoes, are the common hosts.

The Ebola Virus is the most famous Virus from the group known as the Filoviruses (known for their filamentous shape). Ebola has been previously known as Ebola Haemorrhagic Fever, and is the cause for the Ebola virus disease. It has an extremely high mortality rate, ranging between 50%-90%, causing it to be a very dangerous disease if caught. There is currently no licensed Vaccine to help prevent the disease, and has disastrous effects on the bodies cells, vascular system and immune system.

Ebola is the virus Ebolavirus (EBOV), a viral genus, and the disease Ebola hemorrhagic fever (EHF), a viral hemorrhagic fever (VHF). The virus is named after the Ebola River Valley in the Democratic Republic of the Congo (formerly Zaire), which is near the site of the first recognized outbreak in 1976 at a mission hospital run by Flemish nuns. It has remained largely obscure until 1989 when several widely publicized outbreaks occurred among

It is vital to understand deadly viruses and their history in order to prevent future outbreaks. Ebola leaves very few clues after annihilating its victims, so it is incredibly important to analyze those clues. Ebola’s close relationship to monkeys contains key knowledge that could hold the secret to its success. Paying close attention to how Ebola is spreading and mutating could lead researchers to the answer for preventing the contraction of it. Discovering where and how the virus first emerged could lead to Ebola’s end.

Ebola is described by the author in deep detail telling the progression of which it goes through. It starts with a headache and backache and ends with all of your internal organs failing “bleeding out” like Charles Monet. There are four filoviruses: Ebola virus (EBOV), Sudan virus (SUDV), Marburg virus (MARV), and Ravn virus (RAVV). They are all Level 4 biohazard, which means they are extremely dangerous to humans especially because they are so infectious, have a high death rate, and there are no medicines, treatments, or cures.

While Ebola is not an airborne virus, it can be transmitted through direct contact with an infected person’s fluids, such as blood, urine, vomit, sweat, semen and sexual contact (Nevins, 2014). With these deadly symptoms and ease of transmission, the Ebola virus can quickly wipe out an entire community. Yet, scientists have found that the severity of the disease in humans varies widely, from rapid fatality to mild illness or even asymptomatic response, further complicating the ability to quickly identify infected patients and reduce the possibility of transmission (Kolata, 2014). Moreover, the virus has different strains and mutates according to the specific environmental conditions in which it exists (Peters et al., 1991).

Ebola Zaire, arguably the deadliest known virus strain on earth, held a mortality rate up to ninety percent in the past, and is the hottest type of Ebola Viral Diseases. In addition, there are four other types of Ebola species: Ebola Sudan, Ebola Ivory Coast, Bundibugyo ebolavirus, and Ebola Reston. Notably, the earliest of Ebola outbreaks being from Ebola Sudan and Ebola Zaire, both erupted during 1976 in Africa. Previously known as the Ebola haemorrhagic fever, these virus are known to cause tremors and convulsions in its host, resulting in the splattering of blood which is used as its strategy for transmission. Other ways of contracting Ebola is through contact with patient’s bodily fluids and aerosolized secretions in the air. Furthermore, the novel The Hot Zone written by Richard Preston, along with online sources from Gale’s database also indicates that virus outbreaks are partly aided through factors such as close

The ebola virus contains RNA which is its genetic blueprint and to replicate it must get ‘help’ by infiltrating host cells. These host cells are protected by a membrane so to enter the cell the virus attaches itself by a glycoprotein that’s sticks out from its surface to the nutrients the cell requires for survival. Macropinocytosis, a non-specific engulfing process, is thought to be the most likely mechanism that the ebola virus uses to gain entry into the host cell. Once inside the cell the RNA of

The filovirus family encompasses two genera: Ebolavirus and Marburgvirus; note that filoviruses are zoonotic, and have recently been traced to some species of African bats (CDC 2014). Currently, there are four species of ebolavirus that cause disease in humans: Ebola virus, Sudan virus, Tai Forest virus, and Bundibugyo virus (CDC 2015 B, 1). For the purposes of this scenario, Ebola virus will be the agent of focus and use. Symptoms of Ebola virus infection range from common illness characteristics, such as fever and fatigue, to the more detrimental characteristics of unexplained bleeding, vomiting, diarrhea, and body pains; symptoms can appear anywhere from two days to three weeks after exposure (CDC 2015 B, 1). Transmission of infection occurs through direct contact between an individual’s mucous membranes or broken skin and body fluids of an infected person (CDC 2015 A). Body fluids can include sweat, saliva, blood, semen, and urine, amongst several others. The US Centers for Disease Control and Prevention has stated that “Although … the viruses display some capability of infection through small-particle aerosols, airborne spread among humans has not been clearly demonstrated”

It is one of three members of the ‘Filoviridae’ family and comprises of 5 distinct species, three of which are fatal to humans. These fatal species are the ‘Zaire Ebolavirus (EBOV)’, the Reston Ebolavirus (RESTV), and the Sudan Ebolavirus (SUDV). Due to the difficulty in obtaining samples and studying the disease because of the remote areas in which it outbreaks, the cause of Ebola is not yet defined. However, it is greatly suspected that fruit bats carry and spread the virus (through their droppings) without being affected. As mentioned above, the virus is then transmitted to humans through contact with the infected bodily fluids of an infected organism or

As with any infectious disease, whether it originates from a virus, bacterium, or fungi, there is the possibility that it will become an epidemic. For centuries, deadly diseases have threatened to infect and possibly eradicate mankind. The Ebola virus, which causes an extremely fatal hemorrhagic fever, is considered to be one of the most aggressive contagions in the world. The Ebola virus is a member of a family of RNA viruses known as, “Filoviridae” and is composed of multiple distinct subspecies (Bausch et al. 2007). It causes Ebola Virus Disease, a fairly new disease that plagues multiple poor countries within Africa. The virus mainly attacks the lymphatic system, but also severely damages the reproductive and reticuloendothelial systems. The Ebola virus disease causes muscle pain, weakness, limited kidney and liver function and extreme blood loss due to failure of blood clotting.

Ashton Nicholas SPC 205 Informative Speech Outline Ebola Virus General Purpose: To inform. Specific Purpose: To explain to my audience research and facts about what Ebola is, what the symptoms and treatments are, how Ebola is spread, and where Ebola is in the world today. Central Idea: Research is helping us to discover and learn all the facts about Ebola. Introduction I. Attention-Getter:

The Ebola virus is one of few viruses labelled into the haemorrhagic fever Filoviridae and is classified as an RNA viral fever. Consequently, word filo originates from the Latin meaning threadlike which structurally explains the physical appearance. (Weissenhorn, W. Dessen. A Calder, L. Harrison, S. Skehel, Wiley, D. C. Molecular, 1999). Due to the highly pathogenic nature of the virus, the Filoviridae is associated with two main species; the Marburg-like virus and the Ebola-like virus. The Ebola virus is

Ebola is a virus in the family Filoviridae and the genus Ebolavirus. Five virus species have been identified, four of which are known to cause disease in humans: Ebola virus (Zaire ebolavirus); Sudan virus (Sudan ebolavirus); Taï Forest virus (Taï Forest ebolavirus, formerly Côte d’Ivoire ebolavirus); and Bundibugyo virus (Bundibugyo ebolavirus). The fifth

The Ebola is a virus, an infective agent which typically consists of a protein coat that contains nucleic acid, and multiples within a host’s living cells. A Virus cannot be seen by a light microscopy due to its small size. The Ebola virus is a member of the Flioviridae family, which contain single, linear, negative-sense ssRNA (ss meaning single strand) genomes that house the cells genetic material. The tubular Ebola virions are normally 80 nm in diameter and 800 nm long. In the center is the necleocapsid, a capsid that holds all of the cell’s nucleic acid, which in this case is a spiral ssRNA genome. Each genome has a length of around 19kb, and codes for eight proteins, seven structural and one non-structural. The nucleocapsid is throughout