The Function and Importance of the Liver in the Body

As the Directors at the Sharp Rees Medical Facility, we will be talking about the liver. The liver is a very important organ in the human body as it does not just perform one function but is involved in multiple tasks. Some interesting facts about the liver; it weighs under five pounds, it has a shape like a half football and everyone is born with one. Just like most other disease or disorder, if the liver has not been taken care of properly there are many negative outcomes that can affect and destroy the liver. There are many complications when the liver is abused or damage for example cancer, hemochromatosis, gallbladder or

Ideal cardiovascular health consists of seven factors, and very few individuals in the U.S. population actually meet all seven factors. The liver is also a critical organ in that it is essential for metabolic activities, and metabolic complications of the liver related to obesity result in non-alcohol-related fatty liver disease in both child and adult

According to the Merck Manual (2013), hyperlipidaemia is the increased synthesis of hepatic lipoproteins. Marieb (2012) explains that lipoproteins enable fat, fatty acids and cholesterol to circulate in the blood stream. They cannot do this alone due to their insolubility so they use lipoproteins as a type of transport. Nelson (2013) highlights four different varieties of lipoproteins which are chylomicrons, very low density lipoproteins (VLDL), low density lipoproteins (LDL) and high density lipoproteins (HDL).

In the presented case scenario, we have Mr. Gil Martin who is a 55-year-old Hispanic male. He comes in to the clinic today with complaints of weakness, fatigue, and loss of appetite. A student nurse will be precepting your assessment of Mr. Martin and when collecting subjective and objective data it is important to pay close detail to all findings. Ultimately this patient was diagnosis with cirrhosis, which is an abnormal liver condition that leads to irreversible scarring of the liver (National Institute of Health [NIH], 2017), so during assessment we should pay attention to details leading to this diagnosis.

This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the

Liver sections were stained in an Oil-Red-O solution to visualize lipid and structure. Using the Folch, method, livers, were homogenized in a 2:1 solution of chloroform and methanol and then mixed in assay buffer for colometric assay. Plasma was isolated from the blood using centrifuge. This was used to quantify HDL, LDL, and triglyceride levels. Lung and skin sections were stained to observe the structure of collagen.

In the United States, about 31,000 people die from cirrhosis each year. One in 10 million Americans has some form of liver cancer. “Hepatitis C, fatty

The World Gastroenterology Organization (WGO) has recently declared NALFD as most common cause of liver disease. Obesity is an increasing problem not only in the UK but worldwide. An estimated 26% of the adults in the UK are considered to be obese 1, 2. Obesity induced metabolic syndrome may lead to NAFLD, which can progress to Nonalcoholic Steatohepatitis (NASH), and in turn to advanced fibrosis and an increased risk of Hepatocellular Carcinoma (HCC) 2, 3.

Many patients believed that they can take responsibility for their own health and even when you can do something to improve your health always some good medical opinion is always valuable. If you’re taking any medications or even vitamin’s we advise you to see your doctors to see if those pills are the best for you. It is important to research data on the medications that we are taking and if this are regulated by the U.S. Food and Drug Administration (FDA). We don’t want to hard your liver more. Instead of, we can find alternative ways to take care of your liver and one way will be see if you’re taking something that can harm your liver. In addition, is very important to stop the consumption of alcohol because that can cause you to be more prone to some diseases. In your case, it can cause more damages to your liver and lead you to unfortunately consequences. Moreover, your medical history tell us that one of your parents had hepatitis before past away. This can be one factor to consider in your health based on your recent damage to your liver. It is important to look for signs that can tell us if you had this

Giving the fact that NAFLD is usually an asymptomatic disorder, it is often unrecognized in everyday clinical practice. Namely, most patients with NAFLD have no symptoms, and aminotransferase levels which are used as a marker of liver damage, are within normal values in almost half of all patients. NAFLD is strongly associated with type 2 diabetes mellitus (T2DM) and has been linked to increased cardiovascular disease (CVD) risk. It is characterized by insulin resistance and mitochondrial dysfunction6. Indeed, there is a gradual increase in the severity of insulin resistance in the range of NAFLD which may contribute to the evolution of liver damage. Also, it is associated with an increased risk of kidney disease in subjects with multiple CVD

Scoliosis of the liver or nonalcoholic fatty liver is the accumulation of fat in the liver of people who drink little to no alcohol. Instead, the liver is damaged due to weight gain and unhealthy eating. Glucagon, which is produced by the pancreas, promotes the liver to release the glucose into the bloodstream. When the pancreas is not functioning properly, and excess of glucagon is released; promoting the liver to overwork too. For reasons not completely understood, in many people with Type 2 Diabetes, glucagon levels stay higher than normal after a meal. The liver then stores excess glucose for later. High glycogen levels cause the liver to produce unnecessary glucose, which contributes to high blood glucose

Liver disease is a big national problem. Millions of people have it. One of them is my Aaron, my brother. Aaron got diagnosed with liver disease in May 2016. We first noticed something was wrong when his running times were getting worse and worse. A couple days later he had yellow skin, so we took him to the doctor, and they sent us to a the Children's Hospital in Milwaukee. The doctor told us that he did have cirrhosis in the liver, which is a form of liver disease. Some people say just get a liver transplant, and some say they have to take medication. With the type of liver disease Aaron has. It won't matter if he gets a transplant. The new liver will get diagnosed again, and hde will have to do all the procedures and medication all over

Deposition of lipid within the liver represents part of an abnormal lipid partitioning pattern, most commonly associated with increased intra-abdominal fat. The typical obese child with NAFLD will usually manifest other components of the insulin resistance syndrome such as dyslipidemia, hypertension and altered glucose metabolism. As liver steatosis itself is usually asymptomatic, a high index of suspicion for its presence should be present in obese insulin resistant kid who present with dislipidemia or altered glucose metabolism or manifest anamnesttic or physical signs that suggest the presence of insulin

In the absence of the glucose 6 phosphate, glucose cannot be released from the liver. This is a causing factor of fasting hypoglycemia (Michael W King, PhD). An increase in fatty acids, caused by glycogen storage disease, leads to increased triglyceride production. This causes high cholesterol, ultimately leading to hyperlipidemia. A key factor in glycogen storage disease is hepatomegaly, which is an abnormally enlarged liver. This most often results from the hyperlipidemia.

Chylomicrons carry dietary fat from the intestine to the circulation. They deliver triglycerides to peripheral tissues. The resulting cholesterol-rich chylomicron remnant is taken up by the liver. The liver also synthesizes fatty acids from glucose in times of dietary excess, and then these are stored as triglycerides. Fatty acids that are not converted to triglycerides or used in the synthesis of other molecules are oxidized to ketone bodies in the mitochondria or in the peroxisomes. Microvesicular steatosis in hepatocytes is a sign of mitochondrial or peroxisomal disease or drug