The Function and Importance of the Liver in the Body

793 Words Feb 17th, 2018 3 Pages
A foretime, the risk of liver intoxication is elevated due to some factors such as frequent use of pesticide agent, recurrent exposure to environmental toxins and regular use of chemotherapeutic agents. Meanwhile, non-alcoholic fatty liver disease is a pathological condition which occurs in individuals who do not consume large amount of alcohol (< 20g ethanol/d per day) with excessive accumulation of triacylglycerols in the liver (Bhatia et al., 2012; Kawasaki et al., 2009). Triglyceride is a form of lipid (Kawasaki et al., 2009). In past 30 years, NAFLD emerges as a chronic health burden and epidemic of this disease is worldwide (Erickson, 2009). Therefore, it term as a “young” disease because severity and spectrum of pathogenesis spread globally in short term (Mahaling et al., 2013). Moreover, the non-alcoholic fatty liver disease is wide spectrum which range from simple steatosis to steatoshepatitis with fibrosis and at last cirrhosis. The accumulation of the lipid or fat in the liver cell (hepatocyte) is known as a steatosis. Meanwhile, combination of liver inflammation or injury present with steatosis term as steatohepatitis (Panchal et al., 2011). NAFLD not only emerge as a hepatic disorder in the United State, indeed it common health manifestation throughout the universe. In general US population, around 20% are suffering from this disease and most of them…
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