The Genetic Inheritance And Discovery Of Rheumatoid Arthritis

"Rheumatoid joint inflammation is an interminable infection set apart by irritation of the joints, frequently influencing the hand joints and both sides of the body in the meantime" (Royal Australian College of General Practitioners, 2009).

Rheumatoid Arthritis or “RA” is an autoimmune disorder where the immune system mistakenly attacks its own body tissues. This disease affects the lining of joints causing pain and swelling. Eventually the swelling can lead to bone erosion and joint deformity. RA can happen to anyone at any age, but the majority of people who have to endure this disease are women over the age of 40.

Rheumatoid arthritis can occur in all races and ethnic groups. Although the disease often begins in middle age and

Rheumatoid arthritis affects the joints in the wrists and knuckles, though it may occur in any joint. It spreads throughout the body and damages connective tissues and organs. It will eventually, if unchecked, stiffen the joints in deformed positions. In this disease inflamed tissues erode the bones and cartilage.

Rhematoid Arthritis – Is an autoimmune disease which can cause chronic inflammation of body`s organs, joints, and the surrounding tissue of the joints. It can

Juvenile arthritis is a term used to put all the “autoimmune and inflammatory conditions” that anyone under the age of 16 has (Juvenile Arthritis). With almost 300,000 children being affected with juvenile arthritis, it’s easy to believe they all carry the same struggle and pain (Juvenile Arthritis). However, there are many different types of juvenile arthritis that children battle with. The most common forms of juvenile arthritis are juvenile lupus, Kawasaki disease, and Rheumatoid arthritis (Juvenile Arthritis).

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

There are different types of arthritis such as gouty arthritis which causes a swelling usually in the big toe, psoriatic arthritis that often occurs along with psoriasis and reactive arthritis which usually involves the eyes, urethra and joints. Juvenile arthritis is an umbrella term used to describe any form of childhood arthritis or arthritis-related conditions which affects people under 16 years old. The most common form of childhood arthritis is juvenile chronic arthritis (JCA) which is also referred to as juvenile rheumatoid arthritis (JRA). Individuals who suffer from JRA experience stiffness and joint inflammation that result into swelling, warmth, soreness and redness of the joints. JRA, also

Rheumatoid Arthritis has been subject of numerous studies and researches in the look for a better understanding of how it effects the individuals diagnosed with it. There is a higher incident of females diagnosed with RA than male as well as a relationship with genetic and environmental factors involved. Around one percent of the world population is affected by RA; therefore, diverse studies have been performed to understand how the lives of the diagnosed patients can be impacted by the disease. For example, how RA affects the mobility, safety and activities of daily living in general as well as the development of interventions to better approach RA. On

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

Juvenile Rheumatoid Arthritis (JRA) is a chronic and progressive autoimmune disorder of the joints. In JRA the joints become stiff, swollen, and inflamed causing pain and loss of movement. The cause is thought to be genetic and/or related to environmental factors which are still not understood. Because of its origin not being well understood, JRA is also called juvenile idiopathic arthritis. The body has abnormal immune responses wherein it attacks normal cells and tissues causing damage to the joints (McMahon Anne-Marie, 2011).

Juvenile idiopathic arthritis (JIA), previously known as juvenile rheumatoid arthritis (JRA), is an autoinflammatory disease that begins before the age of 16. (2) The cause behind JIA is currently unknown. Symptoms of JIA are a fever (a rash usually accompanying the fever as well), enlarged spleen, presence of arthritis, and also always a sign of systemic inflammation

“Rheumatoid arthritis is a type of chronic arthritis that occurs in joints on both sides of the body, such as both hands, both wrists, or both knees. This symmetry helps distinguish rheumatoid arthritis from other types of arthritis”. If a joint is deemed as arthritic that means that there is inflammation within the joint. Inflammation within a joint can cause swelling, redness, warmth and pain within that joint. Rheumatoid arthritis primarily affects the joints, but may also affect the skin, eyes, lungs, heart, blood, or nerves. Rheumatoid arthritis can present itself in many different ways. For some, joint symptoms develop gradually over several years, while others may develop quickly. Some people are affected by rheumatoid arthritis for a short

Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease that is systemic in nature but primarily targets and damages the synovial joints. It is characterized by painful, swollen, stiff joints, which manifest primarily in the hands, wrists, elbows, knees, ankles, and feet. RA is more common among women than men and increases in prevalence with age, however it can also occur in young adults and children (Lee & Weinblatt, 2001).

Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.