The Health Of The Livestock Production Of Poultry Carrying An Infectious Disease

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The Acute phase proteins are produced as the develop of a response caused after a variety of conditions stimulated by inflammatory cells producing chemical substances that activate specific organs to produce these proteins to reconstitute homeostasis and thus restore the injured tissue. Even though the Acute Phase Response generated is not specific for each determined disease, the measurement of these proteins in an animal may indicate the occurrence of an unhealthy condition, and a further diagnosis and prognosis of the illness could be accomplish. Regarding veterinary public health, the livestock production represents a significant field from where products for human consumption are provided. Thus, the measurement of these proteins in…show more content…
These are plasma proteins which are released into the blood stream, mainly produced in the liver by the hepatocytes (Cray et al., 2009) as part of the Acute Phase Response (APR), that either increase or decrease in response to the tissue damage (Jain et al., 2011; Stahl, 1987; Gruys et al., 2005). The APR is a non-specific and complex systemic reaction, part of the early-defense or innate immune system, which is triggered by different stimuli such as infections, trauma and inflammations in order to reconstitute homeostasis and induce healing (Cray et al., 2009; Tothova et al., 2014). As well as in humans, APP in animals are sensitive to similar triggering events in response to inflammatory stimuli. A variety of APP have been recorded, such as: fibrinogen, haptoglobin (HP), serum amyloid A (SAA); C-reactive protein (CRP); ceruloplasmin (CER), major acute phase protein (MAP) and α1 acid glycoprotein (AGP) (Stahl, 1987; Gruys et al., 2005); differentiating their levels according to each species (Cray et al., 2009; Eckersall and Bell, 2010). Thus, APP have been described for their application in human medicine to diagnose and prognosticate different inflammatory and organ diseases. However; altered levels of APP monitored in animals might provide an alternative method to measure conditions or situations that may be influencing the concentration of these proteins in plasma (Tothova et al., 2014). For instance, in livestock; APP have been presented as markers of health
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