The Health Threat of Antibiotic Resistance Essay

One big factor in the resistance bacteria show towards antibiotics is antibiotic concentration. Usually, if large amounts of an antibiotic are attacking a bacteria it will stop the multiplication process and even kill it off, but if there is small amounts of antibiotic it will allow the bacteria to continue to spread. You can find many bacteria in a jelly-like biofilm which provides a shield to them.

A couple times a year local and national mass media put the spotlight on problems connected to antibiotic overuse. Some people consider those problems to be real and serious, and others think that the discussed topics are nothing more than new “fashionable” subjects to talk about, distracting people from “real” problems, such as climbing gas prices or war expenses. Meanwhile, antibiotic overuse continues as a common practice among US doctors and agribusinesses for the last 20 years. The practice of antibiotic overuse has put patient’s health at risk, contributed to antibiotic resistance and increased bacterial mutation to a new, stronger level; as well as it hitting the economy with new costly expenses in health care. It is time to stop

Antibiotic resistance evolves in bacteria. Charles Darwin created the theory of evolution which focused on natural selection being the key factor of how things change. Natural selection is when organisms that are better suited to the environment are able to reproduce successfully. Evolution is descent with modification. Bacteria can become resistant to antibiotics by a mutation. The bacteria that did not die from the antibiotic inherited the gene from an ancestor that made it resistant. Since the other bacteria is dying faster than the resistant bacteria, the resistant bacteria are able to multiply

Antibiotic resistance is when microorganisms, such as bacteria, are able to survive an exposure to antibiotics and these bacteria are now resistant to the effects of these antibiotics. Antibiotic resistance in bacteria has been an issue since antibiotics were discovered. The fact that bacteria can become resistant to our medical treatments such as antibiotics is a natural evolutionary process, but there are certain human contributions that definitely speed up the process. For example, one of the main contributions that will be discussed is the problem of over prescription of the antibiotic drugs. The

Furthermore, in the past 10-15 years, Clostridium difficile infection (CDI) has emerged as an increasingly important infectious disease worldwide. C. difficile is an antibiotic-associated bacteria that causes asymptomatic

When antibiotic is used most of the bacteria die but a few bacteria with antibiotic resistance gene survive and reproduce and pass this advantage to their offsprings. This selective pressure exists naturally, however antibiotic misuse can be accused for fastening the spread of the antibiotic resistance gene [Refer to figure 2] (Learn Genetics 2015). Consequently, inappropriate antibiotic intake will lead to a greater chance of superbugs being developed. Antibiotic resistance can be defined as a new ability which a bacterium has developed to stay unattached in the presence of an antibiotic that was previously effective to destroy the bacterium (ABC science 2015). Four key mechanisms that has been identified for bacterial antibiotic resistance can be listed as: producing enzymes that inhibit the functionality of the drug, reducing the effectiveness of the drug by producing targets against which the antibiotic, reducing the permeability of the drug into the bacterium and active export of antibiotics using various pumps (Pogson 2012). All these mechanisms can be developed by any of the bacteria when the corresponding mutated gene of antibacterial resistance is received. The genes code for specific proteins, and variation in the gene leads to alteration of the shape of proteins. This leads to changing the functionality

Widespread use of antibiotics has been very controversial in the media as well in the general population. Due to these controversies, it is very misunderstood to how antibiotics work leading to many patients in the hospital setting wanting to take them when it is not necessary or refusing to take when it is necessary for their survival. Some of this controversy is due to antibiotic resistance, which has spread an alarming rate in the 21st century (Walsh, 2000). Antibiotic resistance is the result of very strong bacteria or microbes that are resistant to the antibiotic prescribed and those microbes accumulate overtime by their survival, reproduction and transfer, leading to increased levels of antibiotic resistance.

(KArch) We as human-hosts are not just helpless victims, our continuous reliance on antibiotics treatment helps contribute to the ever growing problem. The increased and inappropriate use of antibiotic therapy is the main cause of these antibiotic resistant bacteria. Patient this day and age are often prescribed pills for every condition. Patients come into doctors’ offices demanding antibiotics and healthcare providers are filling these orders. This in turn contributed to this growing chain of antimicrobial resistance.

Antibiotic resistance is, in simplest terms, just natural selection – but at a hugely exacerbated rate. We can see the effects of natural selection in ourselves; that’s why we don’t have webbed fingers, because they didn’t exactly benefit the terrestrial human race. But while it takes human beings 20-30 years to reproduce, it takes most bacteria 20-30 minutes. Think about that for a second. By reproducing every 20 minutes, a single E. Coli bacterium can create 70 billion new bacteria in just 12 hours. About 2% of those bacteria will have some type of mutation, and

The misuse of antibiotics has the potential to set society back in time to the dark ages. It is time to end the careless use of these valuable antimicrobial that so many take for granted. Antibiotic resistance continues to expand and evolve and solutions to this epidemic need to implemented. By establishing stewardships, educational programs, and restrictions it teaches the severity of this issue and action that must be taken in order to decrease resistance. Antibiotic resistance is a multifactorial issue. Introducing preventative measures in hospitals will be most effective in reducing resistance, as well as eliminating the trend of misusing antibiotics.

Antibiotics are used incorrectly and become resistant when a patient misuses it. By overusing or underusing antibiotics, the bacteria will adapt and become resistance to the antibiotic. When people stop taking antibiotics to treat an infection before all the bacteria is wiped out, the existing bacteria survive, adapt, and multiply. When patients overuse the antibiotics, the antibiotics kill all the bacteria, including the good ones that help defend the body. Some of the bacteria will remain because of mutations that provide them with immunity and will continue to reproduce with developed resistance to the antibiotic, with the antibiotic having no effect and without any good bacteria left. Another way bacteria becomes resistant is through animals that have been given antibiotics. The bacteria can become resistant in animals and be transferred to humans through animal

Take for example MRSA (Methicillin-resistant Staphylococcus aureus), a S. aureus strain that was discovered in 1961 to be resistant to the antibiotic methicillin. Webmd indicates that MRSA has now grown its resistance from methicillin to “amoxicillin, penicillin, oxacillin and many other common antibiotics” (MRSA). This increase in resistance of a methicillin-resistant strain of S. aureus can be attributed to the increasing use and overuse of antibiotics, not only in the doctor’s office but also in agriculture. MRSA is only one of many antibiotic resistant strains of bacteria. New resistant strains are evolving rapidly. According to Dr. Ed Warren, “there are high levels of antibiotic resistance in bacteria causing common infections (e.g. urinary tract infections, pneumonia, bloodstream infections) in all regions of the world” (21).

Antibiotic resistance will kill 300 million people by 2050. Antibiotic resistance appears when an antibiotic resistance loses the strength to effectively manage or kill bacteria and bacteria growth. There are some antibiotics that are naturally resistant to the human body. There are two other ways your body could become antibiotic resistant, 1) by genetics or 2) by acquiring resistance from other antibiotics. Many people ask how antibiotic resistance spreads. It can spread “vertically” which is a new generation that inherits antibiotic resistance genes. It can also spread “horizontally” is when bacteria share or exchange sections of genetic material with other bacteria.

It is vital for the global community to recognize the dangers of antibiotic resistance and the importance of addressing it. According to the World Health Organization (WHO), “antibiotic resistance is one of the biggest threats to global health, food security, and development today” (INSERT CITATION). Before the development of antibiotics, infectious diseases, such as bacterial meningitis and strep throat, killed thousands of people, especially children, a year. These once-fatal diseases are now easily treatable with antibiotics. However, the rise of antibiotic resistance threatens to make these diseases fatal once again. Compounding the issue of increasing resistance is the slow development of new antibiotics. Only two new classes of antibiotics have been developed and placed on the marker in the past few decades (Battle super bugs citation). Antibiotic resistance has tremendous implications for global health and economics, as discussed in this section.

Antibiotic resistance is one of the greatest threats to global health, food security and development today, it occurs naturally, but the pace of its process speeds up its abuse when given to humans and animals and it can harm anyone regardless of age and country of residence (Laxminarayan, et al.2013). According to World Health Organization (WHO), there are 700,000 people death every year because of antibiotic resistance (WHO,2016). A study by the Public Health Foundation in England found between 2010 and 2013 that prescription antibiotics increased by 6 percent and Escherichia coli resistance was recorded by 12 percent for the same period. Antibiotic resistance is on the rise to dangerous levels around the world, and new