The History Of Hemophilia A / B, Inheritance Patterns, And The Treatment Options

When I read, I begin to relate to certain characters. I usually don’t realize it but, once I think about it, I realize that there are many similarities between myself and a character. When I thought about the characters we have read about, I realized that I relate the most to the narrator from “The Scarlet Ibis”. He is determined and wants the best for Doodle. Doodle’s brother is determined.

According to the National Hemophilia Foundation (n.d.), von Willebrand disease (VWD) is a genetic disorder caused by missing or defective von Willebrand factor (VWF), a clotting protein. VWF binds factor VIII, a key clotting protein, and platelets in blood vessel walls, which help form a platelet plug during the clotting process. The condition is named after Finnish physician Erik von Willebrand, who first described it in the 1920s (National Hemophilia Foundation, n.d.). The seriousness of the bleeding varied between family

According to the CDC website, Hemophilia, is a hereditary bleeding disorder which affects mostly males due to X chromosome singularity. Hemophilia is a medical condition in which the blood clotting becomes a challenge for those affected. Symptoms include spontaneous bleeding from injuries or surgery. Blood contains many proteins called clotting factors that assist in blood coagulation, however; those individuals with hemophilia have low levels of either factor VIII or factor IX. The severity of the condition is determined by the amount of factor in the blood thus the lower the amount of the factor, the higher the chances that spontaneous bleeding will occur leading to more severe health complications.

Hemophilia is an X-linked recessive disease in which blood lacks blood-clotting proteins. Females have two X chromosomes, indicating that they are generally carriers and transmit the gene to their sons. People with mild hemophilia bleed after surgery, injury, or trauma. Severe hemophilia produces spontaneous internal bleeding in joints and muscles. Fortunately, medicines and lifestyle changes offers hemophiliacs fairly normal lives. Through learning about hemophilia, I became interested in genetic diseases and finding a cure for those

A genetic disorder that affects the blood vessels when injured that results in clotting is Hemophilia. This inherited disorder is not contagious and is found through various lab tests such as a blood clotting test. The way someone can be aware if they could encounter Hemophilia is simply by viewing their medical history,

Hemophilia is a rare genetic blood clotting disorder that primarily affects males. People living with hemophilia do not have enough of, or are missing, one of the blood clotting proteins naturally found in blood. Two of the most common forms of hemophilia are A and B. In persons with hemophilia A (also called classic hemophilia), clotting factor VIII is not present in sufficient amounts or is absent. In persons with hemophilia B (also called Christmas disease), clotting factor IX is not present in sufficient amounts or is absent. People with hemophilia do not bleed more profusely or bleed faster than normal; they bleed for a longer period of time.

As the best of my knowledge I believe the two year old child is suffering from an inherited disorder called hemophilia. The Mayo Clinic describes hemophilia as a rare blood disorder that lacks sufficient blood clotting proteins. (Staff, B.M. ((n.d.)). Hemophilia. Retrieved September 27, 2016, from http://www.mayoclinic.org/disease-conditions/hemophilia/basics/treatment/con-20029824

A. It 's important to know that hemophilia is not actually a disease or virus. https://my.clevelandclinic.org calls hemophilia "a rare hereditary (inherited) bleeding disorder in which blood cannot clot normally at the site of a wound or injury". This means that it is not contagious, rather it is passed down through genetics. When a hemophiliac gets injured,

Haemophilia is a genetic disorder that is passed through generations on the x chromosomes, that affects the clotting factor in the blood and makes patients more prone to spontaneous and injury-resulted bleeding which is usually internal. According to the Haemophilia Foundation Australia (2015), there are over 3,000 cases of haemophilia in Australia, and more than half the cases are in males. The National Haemophilia Foundation (2013) website shows that cases of haemophilia go back to the 2n d century, where Jewish boys who have records of uncontrollable bleeding leading to death in their family do not have to undergo circumcision, also cases in 10th century Arabia show deaths of males after uncontrollable bleeding due to trauma. The first

The first generations are skipped, although Nicolas (1904-18) was a hemophiliac, neither his parents nor grandparents were. This pattern occurs in several other places of the pedigree, and indicates a recessive mode of inheritance. From the biochemical nature of the defect, scientists have determined that hemophilia is a recessive trait. All the affected individuals are sons, strongly suggesting that the defect is a sex linkage trait. Since males are hemizygous for the X chromosome, more males than females should have the phenotype of

Autosomal recessive inheritance implies that the quality is situated on a single autosome of the autosomes. This implies men and women are similarly influenced. "Recessive" implies that two duplicates of the gene are important to have the characteristic, one acquired from each parent. An individual who has only a single recessive gene is know a "carrier" for this gene or infection, yet they don't have any medical issues from "carrying" one duplicate of the gene. Majority of the individual are not aware that they are carry a heterozygous genetic factor for an illness until they have a baby with it. [1] When mother and father have had a child with a recessive trait or illness, there is a one out of four, or 25% chance, with each consequent pregnancy,

Hemophilia is a problem with the blood in a person that causes them to bleed not any faster than normal, but they often bleed for a longer period. Their blood is missing the clotting factor (a protein in the bloodstream that works to control bleeding). Hemophilia is quite rare; roughly 1 in every 10,000 persons are born with it. Rarely, hemophilia can be an acquired disease which just means a person is not born with it, but will develop it during their lifetime. This rarity occurs when a person's immune system forms antibodies that attack the clotting factor in the blood. The entire antibody population fights against the blood to prevent the clotting factors from working properly.

There are many tests that help diagnose this disorder in a person. One of those is a screening test. Another test is clotting factor tests. On a normal basis, hemophilia is found in your genes when you are born. This disease can be treated in different ways. In my research, I found that you can replace the clotting factors in your blood. You would need to replace them because hemophilia comes from deficiency in you clotting factors. This disorder can be found

The 12th of August 1904 was a great event for the Romanov family, who were the last ruling dynasty of the Russian Empire – it was the birth of their long-awaited son Tsarevich Alexis, the successor to the Russian throne. Unfortunately, the sole heir was seriously ill with an incurable disease called hemophilia. Hemophilia is an inherited disease characterized by the inability to form blood clots properly. In other words, any minor cuts might be almost fatal for people, who suffer from this disease. The condition is passed on to males through females, who do not manifest the symptoms of the disease themselves. The Tsarevich Alexis inherited hemophilia from his mother, the tsarina Alexandra Feodorovna, who was the granddaughter of Queen Victoria.

Going back in history, Haemophilia is also known as “Royal Disease”. This is because Queen Victoria was a carrier of the disease gene and passed it on to her children and