The History and Treatments of the Virus Ebola Essay

* The Reston Ebolavirus was discovered during an outbreak of Simian hemorrhagic fever virus (SHFV) in crab-eating macaques from Hazleton Laboratories (now Covance) in 1989. Since the initial outbreak in Reston, Virginia, it has emerged in Siena Italy, Texas, and among pigs in the Philippines. Despite its status as a Level-4 organism, it is non-pathogenic to humans although hazardous in monkeys.

In late 2013, Ebola virus disease (EVD), a deadly and lethal disease, remerged in West Africa spreading to various countries in the region. In humans, the disease is spread through contact with infected bodily fluids leading to haemorrhagic fever (World Health Organization [WHO], 2015). Originating in 1976 in equatorial Africa, past outbreaks with a few hundred cases had been contained within rural, forested areas in Uganda and Congo (Piot, 2012). In 2014, a total of 20, 206 cases and 7,905 deaths were reported to have occurred in up to eight countries worldwide. Of all cases and deaths resulting from the disease, 99.8% occurred in three neighbouring West African countries - Liberia, Sierra Leone and Guinea (WHO, 2014). With a case fatality rate from about 50% to 90%, and the absence of preventative or curative therapies, the Ebola epidemic has led to overall global alarm and further elucidated existing global health disparities that perpetuated the epidemic with these West African countries.

In 2014, Ebola hemorrhagic fever caused an outbreak in West Africa that officially ended in 2016. The Centers for Disease Control and Prevention (CDC) says, “Ebola is a rare and deadly disease caused by infection with one of the Ebola virus species” (“Ebola (Ebola Virus Disease)”). Ebola is caused when a person is in contact with an infected person’s blood or other body fluids. Prevention of contracting the disease include, not touching the dead body of an infected person, not touching body fluids of an infected person, avoiding places infected people are being treated, not touching bats or nonhuman primates

First discovered in the 1970’s, the ebola virus was contained to West Africa (“About Ebola Virus Disease”). Villagers’ diets consisted primarily of the resources readily available. Among these resources were fruit, vegetables, and animals, namely monkeys. Monkeys carried the ebola virus, and when people ate them, without proper cleaning and cooking techniques, they became infected. Ebola, formally known as Zaire Ebola Virus, is transmitted through bodily fluids like saliva, blood, semen, breast milk, mucus, sweat, tears, feces and urine. ("Ebola in West Africa."). Since it was introduced to a third world country, where hygiene is not regarded as important as survival. Without education, protection and segregated sewage, the virus began to spread. In days people were dying after spreading the virus to those closest to them (Waterman). The bodies, though dead, were still harboring the virus and

Although Ebola was first reported in 1976, little news was released on the outbreaks which had occurred in Sudan and Zaire and which had taken away the lives of 434 people. Then in 1989 there was the Reston incident, where monkeys shipped to the United States from the Philippines, died in large numbers due to what is now known as Ebola Reston, and the virus killed all monkeys. Fortunately that particular strain was not found to be deadly to humans. For now, the Ebola virus appears again and causes large damage in Africa. The horrible disease failed to appeal to those media institution which results in the information interruption, the public do not have an access to the newly information concerning Ebola. The study on the relationship between

Ebola is described by the author in deep detail telling the progression of which it goes through. It starts with a headache and backache and ends with all of your internal organs failing “bleeding out” like Charles Monet. There are four filoviruses: Ebola virus (EBOV), Sudan virus (SUDV), Marburg virus (MARV), and Ravn virus (RAVV). They are all Level 4 biohazard, which means they are extremely dangerous to humans especially because they are so infectious, have a high death rate, and there are no medicines, treatments, or cures.

Although Ebola caught the world’s attention during the 1995 outbreak in Zaire, the first outbreak occurred in 1976. As the chart below displays, 71% of the people infected died as a result of Ebola during this first outbreak (Bulletin of the World Health Organization, 56 (2): 247-270, 1978). With the current outbreak, this ratio has dramatically decreased as a result of scientific research leading to early detection, but the current infected population is more than 20 times the amount of any previous outbreak and this number continues to grow as no vaccine exists to prevent the disease.

Ebola Zaire, arguably the deadliest known virus strain on earth, held a mortality rate up to ninety percent in the past, and is the hottest type of Ebola Viral Diseases. In addition, there are four other types of Ebola species: Ebola Sudan, Ebola Ivory Coast, Bundibugyo ebolavirus, and Ebola Reston. Notably, the earliest of Ebola outbreaks being from Ebola Sudan and Ebola Zaire, both erupted during 1976 in Africa. Previously known as the Ebola haemorrhagic fever, these virus are known to cause tremors and convulsions in its host, resulting in the splattering of blood which is used as its strategy for transmission. Other ways of contracting Ebola is through contact with patient’s bodily fluids and aerosolized secretions in the air. Furthermore, the novel The Hot Zone written by Richard Preston, along with online sources from Gale’s database also indicates that virus outbreaks are partly aided through factors such as close

In the year 1976, Ebola climbed out of its unknown hiding place, and caused the death of 340 people. Fear gripped the victims' faces, and uncertainty tortured their minds. The people of Zaire waited outside clinics, churches and in their homes for a treatment of the horrible disease, but there was no cure. They were forced to watch people die, hoping that they would be saved from the violent death of the Ebola virus. From the year of 1976 to the present date of 1996, researchers have searched for origin and cure of the virus. Scientist have carried out numerous studies and investigations, but no one has been able to find the right explanations.

It is one of three members of the ‘Filoviridae’ family and comprises of 5 distinct species, three of which are fatal to humans. These fatal species are the ‘Zaire Ebolavirus (EBOV)’, the Reston Ebolavirus (RESTV), and the Sudan Ebolavirus (SUDV). Due to the difficulty in obtaining samples and studying the disease because of the remote areas in which it outbreaks, the cause of Ebola is not yet defined. However, it is greatly suspected that fruit bats carry and spread the virus (through their droppings) without being affected. As mentioned above, the virus is then transmitted to humans through contact with the infected bodily fluids of an infected organism or

As with any infectious disease, whether it originates from a virus, bacterium, or fungi, there is the possibility that it will become an epidemic. For centuries, deadly diseases have threatened to infect and possibly eradicate mankind. The Ebola virus, which causes an extremely fatal hemorrhagic fever, is considered to be one of the most aggressive contagions in the world. The Ebola virus is a member of a family of RNA viruses known as, “Filoviridae” and is composed of multiple distinct subspecies (Bausch et al. 2007). It causes Ebola Virus Disease, a fairly new disease that plagues multiple poor countries within Africa. The virus mainly attacks the lymphatic system, but also severely damages the reproductive and reticuloendothelial systems. The Ebola virus disease causes muscle pain, weakness, limited kidney and liver function and extreme blood loss due to failure of blood clotting.

Ebola Virus is a serious transmitted disease by both humans and animals. The disease first appeared in 1976 in 2 simultaneous outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo. The latter occurred in a village near the Ebola River, from which the virus received its name. Ebola Virus is a member of the negative stranded RNA viruses known as filoviruses. There are currently, five different strains of the Ebola Virus including, Zaire (EBOV), Sudan (SUDV), Bundibuguyo (BDBV), Taï Forest (TAFV) and Reston (RESTV). Each of the strains of the virus are very closely related including Reston which only effects animals. Yet, Ebola Zaire is the most highly virulent subtype, often leading to death. All of the different types of the virus are extremely dangerous and often cause death if untreated.

The Ebola virus is negatively stranded RNA type. It requires a polymerse transformation to reproduce. This leaves the virus subject to genetic code errors creating subtypes of Ebola. There are four known subtypes of the Ebola virus. The original subtype was Ebola Zaire (www.netLibrary.com).

The Ebola Haemorrahagic Fever, or Ebola for short, was first recognized as a virus in 1967. The first breakout that caused the Ebola virus to be recognized was in Zaire with 318 people infected and 280 killed. There are five subtypes of the Ebola virus, but only four of them affect humans. There are the Ebola-Zaire, Ebola-Sudan, Ebola-Ivory Coast and the Ebola-Bundibugyo. The fifth one, the Ebola-Reston, only affects nonhuman primates. The Ebola-Zaire was recognized on August 26, 1976 with a 44 year old schoolteacher as the first reported case. The Ebola-Sudan virus was also recognized in 1976 and was thought to be that same as Ebola-Zaire and it is thought to have broken out in a cotton factory in the Sudan. The Ebola-Ivory Coast was

Normally infecting fruit bats, the Ebola virus found a mutation allowing it to spread to humans. This virus is an acute and often fatal illness. This virus first erupted in two outbreaks in 1976 (one occurring in Nzara and Sudan, while the other occurred in a village near the Ebola river, where the virus takes its name.) The current outbreak, starting in West Africa with the potential to spread throughout the world,  is  larger and more complex than previous outbreaks. This virus has caused more deaths than all other past Ebola outbreaks combined. With approximately five people infected with the virus every hour in Sierra Leone alone, how far – and how fast – will the Ebola virus go?