The Human Body Limits Iron Stores

1287 Words Aug 28th, 2014 6 Pages
Genes are small segments of DNA (on a specific locus of a chromosome) that contain the code used to synthesise a protein and mRNA molecule (Khan Academy, 2014). The ‘normal’ function of the HFE protein involved with haemochromatosis is to regulate the production of the protein hepcidin, produced in the liver, which determines levels of dietary iron absorption and the it’s release from storage sites in the body (Haemochromatosis.org.au, 2014). The human body limits iron stores through the HFE protein, however hereditary haemochromatosis is caused by a mutation of the HFE protein in the DNA, means it cannot communicate with the transferrin receptor. As a result, when iron enters the body, the transferrin absorbs the mineral into the cells. Excess iron is deposited into liver, heart pancreas, joints, sex organs and in the joints.DNA is a double stranded molecule composed of sugar, phosphate and four different nucleotide bases; thymine, cytosine, guanine, adenine. These bases (and their organisation) create the genetic code of the body and determine phenotypical features (Khan Academy, 2014). The nucleotide bases must be joined in specific order; A toT , G to C. DNA contains genetic information to make amino acids which combine to make proteins. These proteins determine the physical traits of an organism and control cellular functions (Class Powerpoint).

DNA is located in the nucleus of all cells, and is organised into chromosomes. There are 46 (23…

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