The Human Genome Project Research

Understanding DNA can take a lot of studying and confusion to even get the general idea of the concept. The structure of DNA is very complicated and complex to understand, but researchers James Watson, Francis Crick, Maurice Wilkins, and Rosalind Franklin all developed the idea of the DNA structure in 1953. Deoxyribonucleic Acid is found in the nucleus of the cell. It is a double stranded molecule that contains the genetic code and is the main component of chromosomes. DNA is the blueprint of organisms. Nucleotides are the basic unit of DNA and they are made up of sugar, phosphate, and one of the four basis including adenine,

Throughout the early 19th and 20th century, many scientists have studied deoxyribonucleic acids in order to attain higher understanding over the matter. Johann G. Mendel had figured out and understood the laws of heredity. Friedrich Miescher amazingly discovered DNA in 1869, even though scientists did not understand DNA was the genetic material

In the early 1950s, the race to find the structure of DNA was in full swing. The search was being conducted at three different colleges. At the California Institute of Technology, Linus Pauling,

Over the course of the modern age, the human body was still a mystery waiting to be solved. The body contains secrets one can only hope to discover. Over the twentieth century, scientists tried to understand one of the most complex concepts in the biological field. DNA (Deoxyribonucleic acid) was at the forefront of research. Several theories claimed to have solved the structural concept of DNA. However, it was not until Francis Crick and James D. Watson discovered the true structure, the double helix. However, many potential models of DNA had passed through the biology field until eventual lose of credibility. The past models would contain a fixed detail that would make the entire concept invalid. In James D. Watson book, The Double Helix, he illustrates his path amid incorrect theories until he reaches the model that is taught around the world today.

Chapter 1: Genes can be demonstrated as “instruction books for making functional markers such as ribonucleic acid(RNA) and proteins”(Chapter 1, page 4). Distinctively, the four nitrogenous bases to code the gene of DNA is adenine, thymine, guanine, and cytosine. In addition, Rosalind Franklin was among the primitive people to experiment with X rays as a form of molecular photography in order to learn more about DNA and its structure. The structure of DNA taught a constitutional fact about genetics; it stated that the two strands of DNA were complementary to each other. Moreover, DNA replicates in order to make new sets of

In Time Magazine an article states On February 28 1953, James Watson and Francis Crick broke the DNA code and discovered that the DNA strand is double helix and forms like a ladder. They found that cytosine and guanine were paired together and that adenine and thymine were paired. They discovered the building block of life (Wright, 1999). DNA is found in all living organisms.

Scientist in early 1950s James Watson a biologist from Indiana University and Francis Crick a physicist were working at lab to discover the structure of DNA. The primary technique for structural analysis of biological molecules is X-rays. The wave length of X-ray is about the same as the space between the atoms in crystal matters. We learn and know that genetic information was carried on chromosomes made up of DNA and protein. Maurice decided and taken the first x-ray picture of DNA that lead him to suggest the DNA structure might be a helix. Watson was able to rely on Wilkins' research. If he had not, he may have not been the one to discover the structure of DNA. The biggest thing I learned from my research is that scientists can’t make discoveries

On February 28, 1953, James D. Watson and Frances H.C. Crick, Scientists of Cambridge University made a breakthrough announcement for the Science and Medical Field. They had grasped the structure of DNA, the molecule which contains human genes.

The origins of DNA were first discovered during 1857 by Gregor Mendel the "Father of Genetics”, whom was performing an experiment of genetics with pea plants, and would provide a basic foundation towards DNA and Genetics. Friedrich Miescher and Richard Altmann in 1869 were also part of the first people to discover DNA. While testing some sperm of a salmon, they discover a strange substance that they would name as "nuclein", which is known as DNA. This new form of "nuclein" (DNA) would be found to only exist in chromosomes. Frederick Griffith, a researcher, found the basis on DNA, from a molecule inheritance experiment involving mice and two types of pneumonia. His findings were that, when virulent disease is heated up (to kill) and is

in chapter 23, Bobbette learns from her brother-in-law that part of Henrietta is still alive. Her cells are being used in laboratories all around the world and Bobbette had no clue. She raced home telling Lawrence and Day her news. It didn't make sense how was part of Henrietta still alive after all this time. They had seen her being buried, did someone did up the body? Or maybe it was from the autopsy? In June 1973 at Yale the first steps toward the Human Genome Project was held. One of the main problems was the HeLa contamination but in order to sort everything out they needed to test for the specific markers which they needed Lacks family cooperation. Victor McKusick, one of the scientist to first publish Henrietta's name, worked at John Hopkins so he could get the information to contact the family. With access to the family cells it would allow HeLa to be studied in a new way. With accents and education as barriers when a Hopkins assistant called Day said yes because why refuse a doctor. Years later Howard Jones admitted that not enough effort to tell the Lacks family and because they were only taking blood samples no consent forms were needed. The family assumed that since it was a doctor that the tests were needed. Deborah was especially worried since her thirtieth birthday neared the same age her mother died at. She worried often about getting cancer or being injected with cancer like Southam had done to people. She had read about the Tuskgee trials and was very

In 1953 four scientists: James Watson, Francis Crick, Maurice Wilkins and Rosalind Franklin completed a DNA model which they created using observed X-ray diffraction patterns. This model showed how the structure of DNA was able to transmit genetic information from parents to their offspring.

1953, Watson and Crick discovered one of the biggest mysteries of the human body; the DNA

The human genome project is something that I have been very interested with ever since first learning of it. I had heard bits and pieces of what it is about, but my interest was greatly stimulated by Dr. Whited in basic genetics 311 last spring. The discussion that we had regarding the project left me with several ideas and questions about not only the process and ethics involved, but the future of the study of genetics as a whole.

The Human Genome Project basically was a research program that worked on a goal to get an image of human genome and get a better understanding of all a human beings genes. DNA is founded on 4 chemical bases, they turn into twisted ladder shaped DNA molecules. And all the the four bases are what create the genes just placed in different ways and different lengths. One revelation of the human genome project was when they learned that there are about 20,500 genes. The Human Genome Project brought many scientist together around the world and each one was an important factor for the project. It was a publicly funded organization and got funds and support from the Department of Energy and US National Institutes of Health

Due to the DNA’s specificity, samples can be utilised for identification. DNA is a nucleic acid composed of deoxyribose sugar bound to a phosphate group and one of four nitrogenous bases (adenine, guanine, cytosine and thymine). Each section of these three components are referred to as nucleotides, which are joined to the phosphate or sugar of another nucleotide by strong covalent bonds to form a backbone. The nitrogenous bases are joined to complimentary bases of another nucleotide (adenine with thymine, guanine with cytosine) to create a double stranded molecule (Figure 2). To complete the double helical structure, the molecule coils to compact it’s contents. DNA molecules can contain up to two million base pairs, with a human genome containing approximately 3 million base pairs. The random assortment of nitrogenous bases as well as the numerous mutations within certain DNA sequences, results in genetically diverese DNA molecules and genomes between individials.