The Human Immunodeficiency Virus, Or Hiv, The Root Cause Of Aids Or Acquired Immune Deficiency Syndrome?

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Since its discovery in 1981, the scientific community has put up with the struggle of finding a vaccine for the human immunodeficiency virus, or HIV, the root cause of AIDS or acquired immune deficiency syndrome. Although numerous advancements in combating the virus have helped to reverse the epidemic, there is still no known cure. However, recent studies have shown some results that may possibly be the precursors to eradicate the disease. One example would be the trials of a possible vaccine conducted on primates at both Paris-Descartes University and at the University of Chinese Medicine in Guangzhou. Along with finding a vaccine, an alternative method has been proposed in Time Magazine with altering the CCR5 gene in cells, which is…show more content…
SIV is the monkey equivalent of HIV, and therefore serves as a substitute for the HIV virus. The vaccine consisted of inactivated SIV administered alongside the TB-suppressant bacterium BCG, and subsequently with gut bacteria Lactobacillus genus and worked by stimulating the production of a previously unknown group of CD8 T-cells that, while recognising HIV themselves, stopped the monkeys’ CD4 cells from recognizing SIV as a foreign invader, thereby preventing an immune response to SIV. Therefore the SIV did not have the specific immune-activated CD4 cells to reproduce and establish an infection in the body. The SIV/BCG vaccine was given to six monkeys as a vaginal gel, while seven received it as a rectal douche. Eight received it as an oral vaccine which when proved completely effective, were also given another oral vaccine of iSIV plus the Lactobacillus plantarum bacterium. Another eight were given iSIV plus Lactobacillus rhamnosus, a common species found in the human gut and many probiotic supplements. In the results, 15 of the 29 subjects were completely protected from SIV infection. However, vaginal and rectal formulations were not 100 percent protective. In a major breakthrough, monkeys that received the vaccine as an oral formula along with SIV rectally, were unable to be infected. On the contrary, 26 monkeys with no vaccine, inactivated SIV without bacteria or bacteria without vaccine were all affected with the usual SIV. Five who
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