The Human Microbiome Project : A Project Initiated By The Nih Roadmap For Biomedical Research

The relationship between the human gut microbiome to health and disease is strong. Human physiology, metabolism, nutrition, and immune function are all affected by the composition of the gut. If the composition of the gut microbiome is altered in a way that any of these functions are negatively affected, this can lead to disease. The developments of the microbiome, its complexity, and its functionality in health and disease have been extensively studied. In addition, the way in which it is altered has many implications in the cause of diseases, such as bowel disease, obesity, diabetes and cancer.

In the article, "The Ultimate Social Network," Jennifer Ackerman presented data to challenge the first thoughts that people are independent, depending just on the human body to control interior capacities. She stated that the adjustments in the human microbiome are contributing to higher rates of obesity and autoimmune system disorders, prompting it to address regardless of whether we are in charge of our own body.

An important feature of this project is the federal government's long-standing dedication to transfer the technology to private sector by licensing them, awarding grants for innovative research and earning multi-billion U. S dollars that could later be used for medical researchers. To help achieve these goals, researchers also are studying the genetic makeup of several nonhuman organisms. These include the common human gut bacterium Escherichia coli, the fruit fly, and the laboratory mouse. The process for the sequencing of the Human Genome is long and complicated.

The article “Some of My Best Friends are Germs,” by Michael Pollen was a very interesting and informative read. Pollen explains that our bodies house 100s of trillions of microbes. More than 99 percent of our genetic information is microbial. The large number of bacteria that inhabits us weighs many pounds, forming a massive, unexplored world that scientists are just starting to document. These bacteria affect our health as much as if not more than the genes we receive from our parents.

First, a microbiome are the microorganisms in a particular environment, including in parts of the body. All animals have groups of bacteria in their gut. I can't really find a ton out but I have learned is that When the microbiome is healthy and diverse, its effects can be seen in skin, immune, brain, hormone function along with practically everything else directly or indirectly. Wolves Change the

The gut microbiota is extremely diverse – consisting of over 1,000 identified unique species of bacteria. It is indeed difficult to wrap one’s head around it – despite bacteria being microscopically small, and having an undetectable mass, the bacteria of the gut in a human can weigh over 2 pounds! This incredibly diverse mass of bacteria is also mostly unique on an individual basis – over 70% of the bacteria per gut are unique to each person [1]. Thus, the gut microbiota of each individual can effectively function as a unique source of identity.

Before, biologists assumed all microbes are bad for the human body (automatically thought of pathogens), caused many diseases and harm our body fundamental systems. In addition, the biologists think that our body is already built which had all the functions required to maintain our health. However, the attitude has changed over the last decade. The biologists characterized the most prevalent species of microbes in the body, and found out that these collective microbes do not threaten us, and they also are important part of human bodies.

There are major effects in the United States and Europe to help identify the role of microbial communities in the human body. The colon requires a balance of microbial agents that assist with various functions of the body. An imbalance can lead to C.diff., irritable bowel disease (IBD), irritable bowel syndrome (IBS), neurological disorders, and obesity just to list a few. Many of these problems have grown to an epidemic proportion. Both the United States and Europe have started projects aimed at the microbial communities of the body and their roles in our health.

The human microbiome has received more attention in the last few years as scientists have begun to link health and mental wellbeing with these internal synergists. Murray and Manary (2015) define a microbiome as an “ecological community of commensal, symbiotic, and pathogenic microorganisms living inside the body…100 trillion organisms, including anaerobic bacteria, archaea, yeast and parasites.” Humans are born and immediately exposed to these microbes, creating their own microbiome within hours. The natural birth baby inherits microbes of the mother and caesarian section babies receive microbiota of those who handle them first (Ley, 2006). Genes, and the environment from which they are born into, shape their future microbiome (Ley, Peterson,

Identifying microbes using a series of biochemical tests, like those performed by students, is used in a clinical settings for several important reasons other than taxonomy. It is used to determine susceptibility to antimicrobial drugs, gain information for future treatments, identify pathogens in terms of their potential danger, aid epidemiologists in tracing sources of infections, and to accumulate data of interest to those studying infectious diseases (Tortora, G. J., Funke, B. R., & Case, C. L., 2016).

Both in and on our body, there are 10 bacterial cells for every single human cell. This collection of organisms that inhabit the human body is referred to as the microbiome and accounts for nearly 2% of our total body weight.

There is a large number of species of microbes found on the human body. This bacterial organism are found in the skin, mouth, or nose. This lab consisted of the collection of skin bacterial organisms and amplification of the 16s rRNA to construct a small molecular phylogeny of the human body microbiome, or the community of microorganisms that reside in the epithelia of humans. This information could only be acquired through processes such as DNA extraction, amplification of specific genetic target by the polymerase chain reaction (PCR), agarose gel electrophoresis, restriction enzyme digestion, cloning of DNA fragments into plasmid vector, transformation and blue/white clone colony screening. Through the phylogenetic tree analysis

In an unfortunate event, a child may end up in the Intensive Care Unit (ICU) with sever to life threatening ailments. What most people don’t realize is that these children, on average, show signs of weakened immune system and a decrease in their bacteria diversity, also known as their microbiome health. According to a Pennsylvania researcher, Matthew Rogers and his associates, there is evidence that the diversity of critically ill children is far lower when compared to a healthy child. The larger the diversity of your microbiome, the healthier a person is believed to be, which could account for a correlation between a decreasing microbiome diversity and an increase in disease risk.

The global human microbiome market is projected to worth $2.2 billion in 2020 with a CAGR of 9.80% from 2020 to 2024 to cap at $3.2 billion by the end of 2024. There are two main segments in the human microbiome market: Diagnostics and Therapeutics. The human microbiome therapeutics market is projected to grow at a CAGR of 9.20% between 2020 and 2024 and the human microbiome diagnostics market is anticipated to rise at a CAGR of 8.60% from 2018 to 2024.

The Human Genome Project basically was a research program that worked on a goal to get an image of human genome and get a better understanding of all a human beings genes. DNA is founded on 4 chemical bases, they turn into twisted ladder shaped DNA molecules. And all the the four bases are what create the genes just placed in different ways and different lengths. One revelation of the human genome project was when they learned that there are about 20,500 genes. The Human Genome Project brought many scientist together around the world and each one was an important factor for the project. It was a publicly funded organization and got funds and support from the Department of Energy and US National Institutes of Health