The Hypothalamus and The Anterior Pituitary

600 WordsApr 23, 20193 Pages
The Hypothalamus and The Anterior Pituitary The hypothalamus is a part of the brain that has direct control over the release of hormones from the pituitary gland. These hormones are called regulatory hormones. They are considered regulatory hormones because they are molecules secreted into the blood to regulate secretion of anterior pituitary hormones (McKinley 669). Regulatory hormones are produced in the hypothalamus and they travel to the anterior lobe of the pituitary gland; therefore affecting target organs to produce certain functions in the body, and Graves disease is related to this process. The anterior pituitary is an endocrine gland controlled by the hypothalamus in several different fashions. Releasing and…show more content…
CRH acts on cells in the anterior pituitary to release adenocorticotropic hormone (ACTH) which then goes on to act on the adrenal glands to stimulate corticoid metabolism. TRH when it reaches the anterior pituitary it stimulates the release of thyroid stimulating hormone from the thyroid gland. GnRH occurs at the onset of puberty and triggers sexual development and there forward is essential for normal sexual physiology in both sexes. Its secretion occurs in periodic pulses usually occurring every one to two hours. Dopamine has several functions in the brain which include inhibiting release of prolactin of the anterior lobe modulating motor-control centers and activating the reward centers of the brain. GHRH stimulates the release of growth hormone (GH) and target hepatocytes which in turn release the peptide insulin-like growth hormone. This effects the rise in blood glucose levels. Last, PRL regulates mammary gland growth and regulates breast milk production (McKinley 672). The hypothalamus has many distinct functions and effects the body at every moment. Last, Graves disease is when a person’s own immune system attacks the thyroid gland causing a hormone called thyroxin (T4) to produce too much. This hormone as well as others help control and regulate metabolism. Graves disease is a form of hyperthyroidism which essentially causes a person’s appearance and mood to change. It commonly affects
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