The Importance Of A Research On Bipolar Disorder

1009 Words Feb 21st, 2016 5 Pages
The Importance of Mice Research in Understanding Bipolar Disorder

This presentation will be discussing the contributions non-human animal research has made to the field of psychology while focusing on developments in bipolar research. It will begin with an exploration of three research examples that used mice to make discoveries relevant to bipolar disorder. Then my presentation will acknowledge the ethical concerns behind non-human animal research. Next, my presentation will go into an analysis of non-human animal research by discussing its advantages and how valuable this research has been to psychological understanding. The presentation will conclude with a summary of all the points discussed.

Research Example 1
Young, Dulcis, Enkhuizen, Spitzer, Grim, and Geyer (2013) studied the heritability of bipolar disorder by determining if day-length had an exaggerated effect on mice with lower dopamine transporter (DAT) levels (similar to the lower DAT levels found in humans with bipolar disorder). Wild type mice and heterozygous mice (higher in DAT levels) were split into groups and exposed to long-active photoperiod, regular photoperiod, or short-active photoperiod for two weeks. The mice were then tested for depression-like symptoms and risk preference. Mice with reduced DAT expression (like bipolar patients) were found to be more sensitive to the extreme environmental conditions that often lead to mania and depression (See Slide 1). Young et al. (2013) showed…

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