The Importance Of Coumarin

University of Wisconsin biochemistry professor Karl Paul Link and his co-workers first isolated dicoumarin, a molecule in spoiled sweet clover that causes cattle to hemorrhage and die. The discovery led to the development of Dicumarol, the first anticoagulant drug that could be taken orally.(MedicineNet, n.d.). Dicoumarol was a product of the plant molecule coumarin and the successor to Dicumarol was Warfarin(MedicineNet, n.d.). Warfarin is named after WARF, the Wisconsin Alumni Research Foundation, to which

Aspirin was synthesized by reacting salicylic acid with acetic anhydride in the presence of phosphoric acid, H3PO4, as a catalyst:

The goal of this experiment was to synthesize aspirin. In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride. In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group. This method of forming acetylsalicylic acid is an esterification reaction. Since this esterification reaction is not spontaneous, sulfuric acid was used as a catalyst to initiate the reaction. After the reaction was complete some unreacted acetic anhydride and salicylic acid was still be present in the solution as well as some sulfuric acid, aspirin, and acetic acid. Crystallization, which uses the principle of

The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III) chloride to the product.

Coumadin (non specific name: warfarin) is an anticoagulant, or blood diminishing drug, that is endorsed to numerous patients who are at danger for creating blood clusters that could bring about heart assaults or strokes. Warfarin is near the most astounding purpose recently and simultaneous investigations of medications that provoke ER visits and occurring an expansion in healing center based offices with the affirmation of patients. Anticoagulation treatment stances perils to patients and over and over prompts unfavorable solution events in light of complex dosing, fundamental ensuing watching, and clashing patient consistence. As a result, various patients who meet current evidence based principles for warfarin treatment are not being managed

The Autumn Crocus, also known as meadow saffron, is not threatened and is sold as an ornamental plant since it has been cultivated in much of the world (Akram 2012). Although colchicine is typically used for treatment of gout and rheumatic complaints, there has been renewed interest in this medicine by many natural product researchers (Heran 2011). Further research of colchicine derived from the Autumn Crocus as a cancer fighting drug should be conducted due to ability to block cell

grandis in the islands of Hawaii. Coccinia grandis is a potential health asset hidden beneath an identity as a noxious weed, and should be researched and developed for medicinal purposes. According to Voigt (N.d.), C. grandis has shown potential in treating diabetes, cataracts, gonorrhea and in usage as a laxative. A double-blind study was enacted focusing on the effect of C. grandis on blood sugar, with results showing that C. grandis acts as a hypoglycemic agent (Munasinghe, Abeysena, Yaddehige, Vidanapathirana & Piyumal, 2011, p.1). This

Triggers production of other hormones, particularly ethylene and ABA, leading to leaf, abscission, abnormal growth, growth inhibition, and cell death

In this experiment the synthesis of aspirin was used to find the importance of the efficiency of multistep synthesis as well as a means to explore a number or purity tests. The purity tests used in this experiment were a melting point range test, a thin layer chromatography test, a ferric chloride test, and infrared spectroscopy.

This chemical was found as a by-product of the fungus Gibberella fujikuroi (John M Riley, 1997). This acid was developed later and now, synthetic versions of it are available commercially. This Hormone is responsible for growth and development in the plant. Therefore, small concentrations of this plant can help a plant grow faster but too large concentrations can have the opposite effect (Triplantanol, 2011). This chemical comes in the form of a yellowish powder that is dissolved in water and given to the plant (Wikipedia, 2015).

The Pros and Cons of Joint Injuries, Joint Trauma, and Joint Conditions Treated with Cortisone

In vitro enzyme-inhibitory assay-guided fractionation of Polygonum hyrcanicum extract resulted in the purification of 13 phenolic compounds as the active constituents. Based on NMR data, the purified compounds of Polygonum hyrcanicum were identified as quercetin (1) [17], myricetin (2) [17], N-trans-caffeoyl-tyramine (3) [18], quercetin 3-O-α-L-(3",5"-diacetyl-arabinofuranoside) (4) [19], quercetin 3-O-α-L-(3"-acetyl-arabinofuranoside) (5) [20], myricetin 3-O-α-L-(3",5"-diacetyl-arabinofuranoside) (6) [21], (+) catechin (7) [22], (-) gallocatechin (8) [22], myricetin 3-O-β-D-galactopyranoside (9) [23], myricetin 3-O-α-L-rhamnopyranoside (myricitrin) (10) [23], quercetin 3-O-β-D-galactopyranoside (11) [24], myricetin 3-O-α-L-arabinofuranoside

Uric acid is produced through the breakdown of hypoxanthine and xanthine, and this breakdown is catalyzed by the enzyme xanthine oxidase (XO). High uric acid levels in the human body leads to the formation of gout. Gout is commonly treated with allopurinol, a synthetic chemical drug. However, allopurinol elicits many side effects and induces adverse drug reactions. As such, alternative natural drugs have been introduced to reduce side effects. In this study, the XO inhibitory activity of Morinda citrifolia L. leaves were investigated to evaluate the efficacy of this herb as a substitute for allopurinol. Dried, powdered plant materials were subjected to separate extraction using three solvents, particularly 95% ethanol (EE), methanol (ME), and

The proper techniques needed in the synthesis of aspirin and the physical properties of aspirin are determined and applied. The synthesis of aspirin by analysis of its melting point, IR and mass spectrum are confirmed.

The titled 2,5-Di(2H-1-benzo/naphthopyran-2-one-4-yl)thiazolo[5,4-d]thiazole have been synthesized from formylcoumarins and rubeanic acid. Compounds characterized on the basis of IR, 1H NMR and mass spectrometric data. Some of the compounds evaluated for antimicrobial activity against E. Coli and S. Typhi.