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The Importance Of Crohn's Disease

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Crohn’s disease is a chronic inflammatory disease that was once considered as rare in the pediatric population, is presently recognized as one of the most important chronic diseases that affect children and adolescents. About twenty to thirty percent of patients diagnose with Crohn’s disease before the age of twenty years. Crohn’s disease can cause growth failure, malnutrition, pubertal delay and bone demineralization in children. The incidence of Crohn’s disease has increased over the past decades. The age specific rate in North America for children age ten to nineteen years estimated as about 3.5 cases per 100, 000 population. The study of pediatric Crohn’s disease form North America showed the rate of Crohn disease in Wisconsin was 4.56 cases per 100,000 population. The rate of pediatric Inflammatory Bowel Disease (IBD) was higher in boys than in girls. Crohn’s disease is more common in whites than in blacks and is rare in Asian and …show more content…

The development of IBD is very rare in infancy. Inflammatory bowel disease includes, Crohn disease (CD) and ulcerative colitis (UC). IBD manifests during childhood or adolescence in up to 25 percent of patients, however, a small percentage of children may present with IBD in infancy. A published data from epidemiological studies and IBD registries in North America and Europe showed that less than one percent of children with IBD present during the first twelve months of life. Even though the numbers are small, Crohn’s disease is more prevalent than ulcerative colitis in these and other studies. It is also common among infants initially diagnosed as ulcerative colitis or indeterminate colitis to have their diagnosis changed to CD during subsequent follow up. IBD with onset in this age group is likely a heterogeneous group of disorders, and has variability in the clinical presentation and prognosis (Kappelman & Grand,

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