Metabolism and genetics also participate in cirrhosis for example abnormal collection of iron (hemochromatosis) or copper (Wilson's disease) in the liver causing injury, scarring and cirrhosis. Further cause of cirrhosis is the Autoimmune chronic active hepatitis that happens when the immune system attacks the liver and causes inflammation, damage, and cirrhosis. Drugs and chemicals also cause injury of the liver.
The liver’s job is to produce bile, and in return the job of the bile is to emulsify or break down the large amounts of fat, which will assist the body in digesting the remaining food easier (Guyton & Hall, 2011). The next stage is metabolism. The digestive systems job is to metabolize and break down the needed energy for the body and to send the excess wastes to go through detoxification (Guyton & Hall, 2011). As the blood circulates through the portal vein, toxins are removed, to prevent a rise in ammonia levels (Guyton & Hall, 2011). Once all wastes have been removed, the needed vitamins and nutritional needs are stored in the tissues in the body (Guyton & Hall, 2011). The next stage is the production of prothrombin and fibrinogen for coagulation and finally the immunity is for the Kupffer cells to attack and
The gallbladder is a hollow structure which is located right below the liver, and to the right side of the abdomen. Its main function is to store bile, which is made in the liver. The gallbladder is part of the biliary tract. The gallbladder holds the bile when it is not being used for digestion. The bile helps to break down fats during digestion. It also moves waste products from the liver into the duodenum. The bile duct is a long tube that carries the bile. It connects the liver and the gallbladder. Bile is an alkaline fluid. When it is discharged into the duodenum, it neutralises the acidity of the food coming from the stomach.
Fulminant hepatic failure is caused by a serious insult to the body, usually viruses or toxins that overwhelm the liver. The most common cause of fulminant hepatic failure is viral hepatitis.
The liver is located in the upper right portion of the abdomen and is the largest organ. Its job in the digestive system is to produce bile, a substance that breaks up fat particles. It flows from the liver, to the gallbladder, then into the small intestine. It physically breaks up the fat particles.
The abdominal cavity which contains the stomach, most of the large intestine, the small intestine, the gallbladder, spleen, kidney and liver. The small intestine is very important and its job is to digest food and also take nutrients from food to help give back to the body. The gallbladder is a small storage organ also needed in digestion and holds bile products produced by the liver until needed for digesting fatty foods. The kidney is also vital because it helps aid in essential processes such as regulating blood pressure. The liver is very vital and performs multiple critical functions to keep the body pure of toxins and harmful substances. Without a healthy liver, a person cannot survive. Then the pelvic cavity which will contain also portions of the large intestine, reproductive organs, and the urinary bladder. The large intestine is also known for helping during digestion by taking undigested food and absorbing as much water as it can and expels the waste. The reproductive organs play a vital role in the survival of our species. Lastly, the urinary bladder functions as a storage vessel. It is one of the most elastic organs and is able to increase its volume
An acute liver failure happens when the normal function of the liver stops. This happens to people that never before had liver problems. And it happens in a short time of period like a couple of weeks and even days. So it can happen fast and it also causes complications that can be very bad. It causes strong pain on the brain and intense bleeding.
There is no doubt that hepatitis is one of the most dangerous disease and has its bad and negative effects. At the beginning hepatitis is a medical condition that means injury to the liver with inflammation of the liver cells. Simply hepatitis is a disease that includes any type of inflammation of the liver. It may present in acute or chronic forms. Doctors call the inflammation that lasts less than six months acute hepatitis and inflammation that lasts longer than six months chronic hepatitis.
The pancreas is important because it breaks down the fat, carbohydrates and protein from the food we eat. The liver is important because it has many different functions within the digestive system. But liver makes up secrete bile and it cleanses it and purifies the blood coming from the small
Liver is the main organ for the metabolism of exogenous material. As first pass metabolism is the major elimination route of many drugs the drug exposure in the liver can be very high and hence there is a significant incidence of Drug Induced Liver Injury (DILI) associated with this.
Inflammation is a kind of protective immune response of body towards the hazardous stimulants like pathogens, irritants or even dead cells. The components of this protective immune response include blood vessels, mast cells , tumor necrosis factor (TNF-α), tryptase, chemokines, reactive oxygen species (ROS), histamine, bradykinin, prostaglandin and leukotrines, interleukin-1. The inflammatory process is associated with stoppage of harmful stimuli, clearance of damaged tissues and repairing of injury. Inflammation is strictly regulated by the body. The extent of this response determines its positive or negative effect on body. Extremely low level of inflammation can’t stop tissue damage where as chronic inflammation frequently becomes the cause of disease itself.
The most significant agent determining postoperative morbidity and mortality is the capacity of the remnant liver to regenerate . Clinical inquiries found that, following removal of up to 50% of functional liver, there was usually only a gentle and short-lived rise in serum bilirubin and depression of serum proteins indicating sustained briefness of hepatocellular function      . While
Damage or injury to the liver caused by a drug, chemical or other agent. Symptoms vary depending on the degree of exposure and hence extent of the liver damage or injury. Mild liver damage may cause few of any symptoms whereas severe damage can ultimately result in liver failure.
Cirrhosis of the Liver - The failure of the liver cells to renew themselves as they wear out, and are
Sometimes your liver might get exposed towards varied infectious diseases that cannot be treated easily. Toxicity levels of liver need to be controlled immediately and this is only possible by means of proper detoxification. Nowadays, doctors often recommend continuing liver detoxification or cleansing on a regular