The Medical Management Of Alzheimer 's Disease

Alzheimer disease (AD) is the most common cause of dementia in the elderly, accounting for 65–70% of all cases (Jellinger, Janetzky, Attems, & Kienzl, 2008). The other dementias are of the Parkinson 's group, the fronto-temporal group and the vascular group. The total worldwide yearly costs for the treatment and care of patients suffering from dementia are estimated to be around 250 billion US dollars. The lifetime risk for AD between the ages of 65 and 100 is 33% for men and 45% for women with an annual increase of 1–2% in the seventh decade to almost 60% in the 10th decade with doubling every 5 years (Jellinger et al., 2008). AD is incurable, and thus represents a major public health problem. AD represents a challenge to humanity due to its relatively recent discovery, progressive nature of the illness, and complex diagnosis.

Alzheimer’s Disease is a disease of the future. With the growing aged population, this disease, which affects primarily the elderly, will become of increasing relevance to the medical profession. Also, the high frequency of Alzheimer’s, and the high cost in labor, money, and material of caring for its victims shall put considerable burden on the society as a whole. Here, however, these issues are not going to be debated. Instead the pathology of Alzheimer’s will be reviewed to the extent it is known today.

Alzheimer’s disease (AD) is a progressive and fatal form of dementia, frequently seen in the elderly altering their cognition, thought process and behavior. AD is reported in about half of patients that have a dementia diagnosis; one study states that about 10.3% of the population over 65 years is affected by dementia with an increase to almost 50% over the age of 8 (Beattie, 2002). Alzheimer’s disease is not a normal part of the aging process in humans, but rather found in a group of diseases that affect the brain leading to a decline in mental and physical control. AD when diagnosed has a very slow and gradual course, initially affecting the individual’s short term memory (Beattie, 2002). Alzheimer’s disease is the 6th leading cause of death, affecting more than five million people in the United States and is also one of the most common forms of dementia. Dementia can be defined as a disorder of progressive cognitive impairment severe enough to affect daily functions of an individual’s life (Fillit, et al., 2002).

Alzheimer’s disease (AD) is the most common form of dementia known today. The term “dementia” refers to a variety of conditions that arise from the loss of nerve cell function and/or nerve cell death in the brain, including Alzheimer’s disease, vascular dementia, Parkinson’s disease, Creutzfeldt-Jakob disease and other types of mixed dementia. Although all types of dementia arise from neuronal damage and/or death, each form of dementia is associated with distinct brain abnormalities and symptom patterns. Once a patient has been diagnosed with dementia, a physician must conduct further tests in order to determine the exact form of dementia that is present. Recent research indicates that many individuals,

Although Alzheimer’s Disease (AD) is the most widely known cause of dementia in the elderly population, there are many other explanations and clinical diagnoses that

It is a disease that we haven’t cured yet but instead have only come up and still coming up with treatment strategies to alleviate its symptoms. AD was first described in 1906 by a German psychiatrist by the name of Alois Alzheimer whilst he was performing a histophathologic study of his patient’s brain, a patient who had been suffering from dementia. His patient’s brain’s autopsy brought to light the presence of two types of lesions, which are senile plaques and neurofibrillary tangles. He saw a visible difference in the brain tissue for it was severely damaged by these lesions. Since then, our knowledge of AD’s cellular and molecular alterations has increased and we have come up with various hypotheses for AD that may soon help in developing effective preventative and therapeutic strategies. One of the most prevailing hypotheses that have already leaded to a number of therapeutic approaches is the amyloid cascade hypothesis. Hence, the following essay will explore the pathology of the amyloid cascade hypothesis and the evidence for and against it. It will also touch upon current progress in clinical trials that test the

The way one think, act, or even knowing when something is hot is all a part of the Nervous system. The Nervous system is a complex network and cells that carry messages to and from the brain and spinal cord to various parts of the body. The Nervous system comes with many diseases, for example, Alzheimer's disease and Epilepsy.

Alzheimer's is a very common disease that destroys memory and other important mental functions. Working in the Healthcare Profession will allow one to see many different cases of Alzheimer and how it affects everyone differently. Having several family members who have been diagnosed with this disease allowed me to be eager on researching this topic. Alzheimer’s disease usually affects people around the age of 60 and older. It has been said that this disease cannot be cured. Alzheimer’s Disease and Dementia are often mistaken as the same, but through my research I found out that they were completely different.

Alzheimer’s Dementia is one form of dementia. It affects over five million people in the U.S. alone (Latest Facts & Figures Report, 2014). Alzheimer’s is a group of symptoms caused by diseases or disorders. Every 67 seconds someone develops Alzheimer’s in the U.S. (Latest Facts & Figures Report, 2014). Alzheimer’s can take 7-10 years to fully develop. During development the brain reduces in size. Being diagnosed with Alzheimer’s changes the patient’s life significantly. He or she must make many changes in order to maintain a healthy lifestyle.

Alzheimer Disease, the most common form of dementia (to a group of symptoms affecting the brain), is a neurological disorder affecting an individual’s memory, thinking skills, and ability to conduct simply everyday tasks. Alzheimer Disease is irreversible, and no cure has been established. Dr. Alois Alzheimer-the individual in which the disease is named after-detected Alzheimer in 1906 from a woman with abnormal clumps and tangled neurofibrillary (Castellani 2010). These characteristics of the brain are now directly associated with Alzheimer Disease. There are essentially two forms of the disease. Both experience the same symptoms, but one is early onset and the second is late onset. In early onset Alzheimer Disease, symptoms develop as early as 30 years of age. Late onset AD, the most common form, develops at sixty years of age and older. A family history of the disease does improve the individual’s probability of experiencing symptoms. The progression of this paper will consist of the medical changes caused by Alzheimer, how an individual can obtain it, and lastly prevention methods discovered throughout the years.

In 1970, Evelyn Stone was diagnosed with Alzheimer’s disease. However, her husband, Jerome Stone, already knew that something was wrong years before the actual diagnosis. Jerome H. Stone originally grew up to be a businessman, “helping to build the multi-billion dollar Stone Container Corporation,” (Santos) which was his family’s business. As a member of the executive committee of the business, Stone “had the ability to pull people together to coalesce things,” (Megan) and did exactly that in 1979 when he brought together families concerned about Alzheimer’s. “Astonished at how little was known about Alzheimer’s,” (Megan) Jerome Stone created the non-profit organization known as the Alzheimer’s Association just one year after meeting with the families, on April 10, 1980. 36 years later, the non-profit continues to thrive, arguably as the top organization in advancing the care for Alzheimer’s, as it has been able to raise large sums of money through donors and accomplish goals through United States federal legislation.

In most people with Alzheimer’s, symptoms first appear in their mid-60s. It is evaluated by specialists that more than 5 million American may have Alzheimer's sickness. Alzheimer's disease is right now positioned as the 6th driving reasons for death in the United states after heart disease, cancer, chronic lower respiratory disease, accidents and stroke but recent estimates indicated that the disorder may rank third, just behind heart disease and cancer, as a cause of death for older people. Furthermore, Alzheimer's disease causes dementia in numerous elderly individuals and in a few people with Down disorder who survived to age 50. In module three, the author explains how Alzheimer’s disease destroy Charles brain, how he loses more and more mental activities such as knowing, thinking and deciding.

Alzheimer's Disease is a condition that affects 50% of the population over the age of eighty five, which equals four million Americans each year. It is becoming an important and high-profile issue in today's society for everyone. There are rapid advancements being made in the fight against this disease now more than ever, and the purpose of this essay is to educate the public on the background as well as the new discoveries. There are many new drugs that are being tested and studied every day which slow down, and may even halt the progress of the disease.

In 1906, Alois Alzheimer was one of the first to label Alzheimer, however it was referred to as ‘’senile dementia’’ until the 1960s and it was treated as a normal part of ageing (Mastin, 2010). Sperling et al, (2011) suggested that years before the diagnosis of AD, the physiological process associated with Alzheimer’s disease (AD) is already there. Alzheimer's disease is as a major degenerative disease of the brain, responsible for deterioration of the patient’s cognitive and motor function. Up to the present, there has been only treatment treating the symptoms with temporary effect and not a disease free treatment (Horn et al, 1993).

Neurodegenerative disease are characterized by the progressive loss of neurons from specific origins of the CNS .Alzheimer disease(AD) is a neurodegenerative disorder which affect brain regains that control memory and ability to learn. It is estimated that 27 million people are affected word wide and this number is expected to triple by 2050 due to increase of the population life expectancy . AD is becoming one of the most prevalent neurodegenerative conditions worldwide. Although the disease progression is becoming better understood, current medical interventions can only ameliorate some of the symptoms but cannot slow disease progression.