The Most Vital Functions Of The Nervous System

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The most vital functions of the nervous system is to provide information about the occurrence or threat of injury. One of the ways this is done is in form of pain. However, sometimes, established pain can go beyond its protective role, thus becoming a disease in itself than just being a symptom. This condition is called chronic pain. The injury or the precipitating event can be physical (like in case of phantom limb pain or post-surgical pain), infection (as with post-herpetic neuralgia), systemic disease (like with diabetic neuropathy), drug (chemotherapy induced peripheral neuropathy) or can sometimes be unknown (trigeminal neuralgia, migraine, cluster headache, etc.) Even today, the pathological processes involved in genesis, establishment and continuation of such diseases are poorly understood. Eventually, such painful conditions usually remain refractory to available treatments. According to International Association for the Study of Pain (IASP), globally, it has been estimated that 1 in 5 adults suffer from pain and that another 1 in 10 adults are diagnosed with chronic pain each year. Moreover, according to a recent (2014) article in the Journal of Pain, chronic pain is the most prevalent and disabling condition affecting at least 100 million Americans. It is also the most expensive public health condition with annual cost to society exceeding that of combined costs of diabetes, cancer, and heart diseases. Then, we have set of diseases that follow chronic pain. This

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