The Negative Effects Of Oxidative Stress

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Kozakowska et al., (2015) findings show that it is possible for exercises to support special adaptations as regards to the group and vigor of the physical activity engaged. Based on their findings, they hypothesize that the adaptations occur to protect the muscles from disproportionate ROS generation, hence, enhancing the motor activities (Kozakowska et al., 2015). Their findings show that light exercises and warm-up regimens reduced erythrocyte MDA and raised erythrocyte SOD performance in patients with MD who engaged in regular light workouts. This study is corroborated by the study done by Al-Naama et al., (2015) whose findings were that low-intensity exercises was adequate to improve MDA levels and carbonyl protein – which is…show more content…
Some studies suggest that the apoptotic activities cause sequential death of cells through biochemical processes that change the traits of the cells. Some of the changes occur through DNA mutation, swelling of the cell plasma membrane, and the impairment of the mRNA (Rowland & Pedley, 2010). Research in apoptosis has divulged new findings suggesting that the process irrepressible once it begins making it one of the most highly controlled process of the cell functioning (Gießing, 2005). Another study on the role of apoptotic activity divulges that this activity may be started by one of two pathways, namely the intrinsic and extrinsic pathway (Elmore, 2007). When MD patients engage in high-intensity exercises cause a decrease in the production of ROS that makes cells in the intrinsic pathway to self-engage and kill themselves as they are sensitive to the stress on the cells. The death that occurs in the cells in the extrinsic pathway is thought to be due to the activation of the caspases that cause the death of cells and enzymes that debase protein functions. In the case of extrinsic pathway cell death, it assumed that both pathways prompt the death of cells (Elmore, 2007). A research conducted by Rahimov and Kunkel (2013) explored the role of high-intensity exercise on the myofiber membrane in MD. Their study found adverse effects in terms of the weakening of the myofiber membrane. The possible cause for this as they
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