The Oecd Principles Of Good Laboratory Practice

Laboratory Tests – All laboratory tests utilize the following reference unless otherwise specified - Pagana & Pagana (2014)

Animal ethics are vital to all experiments when live or deceased animals are being used. Animal ethics will need to be considered and respected through this task. The current code for Australian Animal Ethics states that animals can be used for the furthering of knowledge throughout various sciences. The code is used for ethical and humane treatment of animals in experiments with animals being used. The daphnia’s will be treated ethically by respecting the change they are enduring and not abusing them to a great extent.

Purpose: The purpose of this investigation is to learn how to write a proper lab report and how to

This is a sensitive issue area in regards to research. There are many types of research that just are not feasible to do with human subjects; therefore the justification for non-human animals come into the experiment. Even though there are many benefits to using animals, many animal rights groups maintain strong opposition to using animals for research. This is why the APA has developed the Committee on Animal Research and Ethics (CARE). It is the responsibility of CARE to audit that all ethics regarding animal usage is followed (“Committee on animal,” 2014). Due to the sensitivity of testing on animals the APA has developed very strict standards regarding usage of animals as subjects. They range from justification, housing of said animal, acquisition, and procedures. These requirements outline absolute necessity in order to reduce the unnecessary usage of animals in testing.

In order to comply with the microbiological criteria of Section "C" of the Standards, samples of finished product or pre-converted materials from the manufacturing plant must be analyzed in a U.S. laboratory certified by FDA to conduct these tests. Samples are to be submitted a minimum of eight times per year.

Animal experimentation is validated simple by the benefits it has created in both our medical fields and the veterinary field. The advancements over the past century are astonishing. Backed by the weight of scientific literature the case that animal experiments can produce scientifically valid results is clear, strong and sustainable. Protesters opinions on these matters often overlook any of the positives about testing, for instance, cosmetic testing is illegal in the UK, the Netherlands and Belguim. Furthermore, primates only make up 0.001% of animals tested on, and cats and dogs are only 0.5%. Also, laboratories are checked on at least 12 times randomly throughout the year to make sure that the high standards of animal care are being kept (Nuffield Council 39). Animal researchers

Linzey, A. (2013).The Ethics of Testing. The Global Guide to Animal Protection, 185-186. Retrieved from http://www.jstor.org/stable/10.5406/j.ctt2tt9r9.122

In the field of scientific research, animal subjects have become a primary source of medical testing. Investigating the effects of these procedures and chemical experiments to generate evidential conclusions is widely disputed by opposing audiences today. Advocates propose the necessity of animal usage in scientific testing for the advancement of human welfare, while critics argue on behalf of the rights available to such animals used in these procedures. Despite the controversial debates and publications written about this topic, the harsh realities of its practice continue to linger. A statistic often supplemented to the context of this issue, reported by the nonprofit organization PETA, says “More than 100

The focus of animal research has been characterized by three criteria, The Three R’s. “’The Three Rs’ are reduction, replacement and refinement. Here in the US, research communities are committed to supporting techniques that reduce the number of higher species used, replace animals with other models wherever/whenever possible, and refine tests to ensure the most humane conditions possible.” (Trull 2). Scientists try to keep the animals from being harmed as much as possible.

Animal research is regulated by the Animal Welfare Act(AWA). The Animal Welfare Act protects animals against mistreatment during experimentation and living in labs. The act protects against mistreatment of animals by enforcing the following rules: minimum housing standards for research animals (enclosure size, temperature, access to clean food and water, and others), all proposals to use animals for research must be approved by an institutional animal care and use committee set up by

Ethics of animal testing is also represented in this article and the methods by which animals face during testing is horrific. They undergo major suffering as they are sometimes exposed to blunt trauma, or they face electrocution.

Under the Code of Professional Conduct, animals should be handled with minimal stress and used only when justified. The National Health and Medical Research Council (2013) corroborate the AVA with codes and governing principles in relation to the use of animals for scientific purposes. In this case, educational purposes. All codes and governing principles were conducted and understood as the dog received treats and was not approached by students in large numbers. Invasive procedures were also not conducted, and if so, it was understood that the whole group could not conduct the technique. The animal was also observed throughout the practical to determine any signs of

In “The Trials of Animals”, Cleveland Amory claims that experimenters have been their own judge and jury for too long and that public oversight is needed when in comes to experiments involving animals (par. 13). While Congress passed the Animal Welfare Act in 1966, with an amendment in 1986 dictating that a member of the “public vote on the laboratory’s animal–care committee” (par. 2), laboratories where experimentation is done with animals are not regularly inspected, and there is rarely a member of the public on the committee. Animals are being used, no tortured, in experiments for which there is little or no human benefit (par.11). I cannot believe that for so long

General safety instructions followed during lab experiments comprising wearing lab coats, safety glasses, and disposable gloves. Also, no open toe shoes allowed in the lab. Generally, pipetting skills are important through all experiment especially for Bradford assays because the absorbance reading very sensitive to bubbles and so the concentration of the samples. Whereas in SDS-PAGE experiment, preparation and fast demonstration is very important to avoid solidifying the gel before transfer it to the cassette. In mammalian gene expression experiment, sterile condition is highly important to evade mammalian cell infection. As previously mentioned mammalian cell grow slowly and yield low protein, hence infection will result in reduced protein expression.

The aim of this paper is to represent the widespread use of animals in research, with a specific focus on evidence of the advantages and disadvantages of using animals in medical research.