The Pathophysiology Of Type 1 Diabetes

Type one diabetes is an autoimmune disease. There are cells in the pancreas that produce insulin, the hormone that regulates the amount of insulin in your blood and

With over 30 million people having diabetes, the prevalence is continuing to rise. An estimated 200,000 American youth are effected by type 1 diabetes and 40,000 new cases are diagnosed each year¹. The rate for type 1 diabetes in youth has increased by 1.8% each year. In comparison, the prevalence for type 2 diabetes in youth has increased at a rate of 4.8% annually². No matter whether diabetes is type 1 or type 2 in children, family involvement is essential for optimal outcomes³.

Diabetes type 1 develops when the immune system attacks the only cells that create insulin, the pancreatic beta cells. Due to the cells being destroyed, the person with diabetes type 1 has to be

For unknown reasons, the body of a T1D attacks the insulin producing cells, called islets, that are formed in the pancreas and destroys them. This type of attack is known as an autoimmune disorder (Diabetes Research Institute Foundation [DRIF], n.d.). Insulin is the hormone that allows sugar to enter cells, and produce energy. The body now sees islet cells as foreign and eventually the pancreas yields little to no islet cells. Once there are no more islet cells to produce the insulin hormone the sugar levels in the blood become high, called hyperglycemia. This disturbance in homeostasis is not like type 2 diabetes (T2D), where the body becomes insulin resistant. In a T2D, the pancreas still produces islet cells and they are still

This disease does not favor one gender over the other, it effects males and females equally. Currently, the origin of diabetes is a conundrum. Although, it is understood that the immune system attacks the beta cells but it is not clear how or why it occurs. It is hypothesized that T1D maybe hereditary and environmental factors contribute to the onset (5). Symptoms prevail in individuals whom have the majority of their beta cells destroyed via a cellular mediated autoimmune response (1).

Type 1 diabetes is an autoimmune disorder, in which the pancreas does not produce insulin. It usually begins in childhood or adolescence. In Type 1 diabetes, the body’s immune system destroys beta cells in the pancreas that produce insulin. Insulin is a hormone that converts sugar, starches, and food into energy. Without insulin, blood glucose levels become too high, which is known as hyperglycemia. To prevent hyperglycemia, people with Type 1 diabetes must take insulin daily to survive. Genetic and environmental factors affect the onset of Type 1 diabetes. [1] According to the American Diabetes Association, a predisposition to Type 1 diabetes is

Type 1 diabetes is usually a progressive autoimmune disease, in which the beta cells that produce insulin are slowly destroyed by the body's own immune system. It is unknown what first starts this cascade of immune events, but evidence suggests that both a genetic predisposition and environmental factors, such as a viral infection, are involved.

This paper will discuss and critically analyze the health problem surrounding Type 1 Diabetes (T1D) among the population. The findings of this paper will be summarized about the epidemiological concepts, the natural progression, and the treatment that can be provided for this pandemic issue. Current statistics and resources will be implemented throughout this paper. In addition, the Best Practice Guidelines will be analyzed and implemented in order to provide effective care for those who are undergoing this specific health complication.

When it comes to avoiding diabetes, only certain types can be avoided while other types cannot be avoided due to the fact that type 1 diabetes is a disease that is genetically inherited and passed on  from parent to offspring thus the only solution to such a disease is to maintain a healthy normal lifestyle in hopes to avoid any complications and negative symptoms, there are many ways a person can change their lifestyle which is discussed farther on in this report under the treatment topic. Furthermore, type 2 and gestational diabetes are developed throughout an individual life time and somewhat inherited due to the fact that individual with relatives with such a disease have a high chance of developing it, but can also still avoid developing.

Type 1 diabetes ‘usually develops in childhood or adolescence’ (WHO 2011, p. 2), and will result in death if the disease is not treated by consistent insulin injection. This type of diabetes is slightly more complex as it is substantially caused by gene mutation (WHO 2011, p. 2). The World Health Organization (2011, p. 2), describes the aetiology of the disease as the ‘autoimmune destruction of the beta cells of the pancreas.’

Diabetes mellitus (DM) is a condition in the body that is related to a faulty metabolism. It means that the body’s metabolism is not functioning properly, which leads to adverse effects in the health. The food we ingest, gets broken down into blood sugar (glucose), which is what fuels our body in the form of energy. This converted glucose needs to enter our cells so that it can be used for energy and growth. And in order for the glucose to enter our cells, there needs to be insulin present, which the beta cells of the pancreas is responsible for producing. This hormone is responsible for maintaining glucose level in the blood. It allows the body cells to use glucose as a main

Type 1 diabetes is a life long auto-immune condition where the immune system is activated to destroy the cells in the pancreas that produce insulin. Scientists are not sure what causes this auto-immune reaction (Vanstone et al. 2015). It can occur at any age, although it is most often diagnosed in children, adolescents or young adults. The immune system incorrectly sees the insulin-producing cells in the pancreas as foreign, therefore it destroys them. The role of these insulin-producing cells is to sense glucose in the blood, and in response produce the essential amount of insulin to regulate the blood sugar (Griffiths & Payne 2014 pp. 390-391). Insulin’s role is to get glucose from the bloodstream into the body’s cells. Without insulin,

Type 1 Diabetes Pathophysiology: Autoimmune- Anti islet antibodies attack through Lymphocyte infiltration and destruction of the insulin secreting beta cells of the langerhans within the pancreas.

Type 1: In type 1 diabetes the cells that produce insulin in the pancreas are destroyed and cannot be made, this type of diabetes usually occurs in childhood due to the autoimmune system attacking and destroying its own cells that produce the insulin, the beta cells in the islet of Langerhans are destroyed and thus unable to produce insulin. This type of diabetes in incurable and is treated with insulin injections.

Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the