The Polio Vaccine
The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The highest number of cases occurred in 1953 with over 50,000 people infected with the virus. When hygienic conditions were poor polio attacked infants. The disease was spread by contaminated water and contact with fecal contamination. Many infants died when the conditions were poor. But as conditions improved the virus spread differently. It was spread more through playmates and family members, the contamination came from the
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Dean William McEllroy talked Salk into joining the university full-time. Though the school's research budget was a grant from the American Society for the Study of High Blood Pressure in the amount of $1,800, he saw the opportunity to do two things. One was to continue the work he was doing on influenza, second was to begin working with the polio virus. A few months after arriving in Pittsburgh, Salk was visited by the director of research at the National Foundation for Infantile Paralysis. The director asked Salk if he would be willing to participate in a polio typing program. "I had no experience working with polio, but it provided me with an opportunity. . ." Salk said in an interview. This gave Salk a chance to get funding, equipment, a laboratory facility, and to hire a staff to work for and with him. Salk's previous work gave him the idea that a killed virus could in fact work when others thought it couldn't. To type the polio virus Salk infected monkeys with polio by injecting it into them or feeding it to them. If a monkey survived it built up antibodies to protect against the virus. The monkeys that survived were then given another type of virus to see if the same antibodies protected against the second type. If it did, it told Salk and his assistants that the two types were related. If it did not, that told Salk that they were not related. Eventually
Polio an American story is a scholarly readable and informative book which covers the lives of many American eminent scientists who struggled a lot to eradicate polio. This book mainly focuses on the mid twentieth century where the people are very eager to find a vaccine to eradicate polio .This book also covers the entire topics from appearance of polio symptoms to post polio syndrome which shows the valuable thesis done by David M. Oshinsky.
Nobody has ever discovered completely how it is that polio is spread. The best evidence suggests that the virus is excreted in the stool and passed through hand to hand or hand to mouth contact by people who do not wash their hands properly or often enough. It was during the first few years of the fifties and many years before then, that health department officials
In addition to health-related advances, such as the artificial heart valve, DNA structure decay, penicillin, and antibiotics. As well, we can not forget the start of the fight with cancer by the memorable world’s first cancer treatment with Cobalt-60 radiation. Although, new surgical procedures were introduced like the first successful kidney transplant and immunizations like typhoid, smallpox, tetanus, and polio vaccines. Polio epidemics had been occurring in the United States since 1916 according to the Centers for Disease Control and Prevention. The viral disease struck even important figures as President Franklin Roosevelt that forced him to use a wheelchair and wear steel braces on his legs privately. “In the 1940s and 1950s, widespread polio epidemics terrorized the nation. Finally, research scientist Jonas Salk developed an injectable vaccine to prevent polio. In 1955 the vaccine became available to the general public. American scientist Albert Sabin then developed an oral vaccine for polio. Safer and more convenient than Salk’s injection vaccine, the Sabin vaccine became the most common method for preventing the disease. The threat of polio nearly disappeared and many more diseases no longer affected the American people” (Appleby, Joyce 2004). Therefore, the treatments and cures of several epidemics and diseases were an important factor that caused the Baby Boom due to the decrease in the children’s mortality rates and their possibility to reach adult
Koprowski’s polio vaccine was given to many children less than one month old, before their immune systems were fully developed.” many of the children were given 15 times the recommended dosage to insure
Poliomyelitis was a highly infectious disease that spread through many Americans in the early 20th century. As a matter of fact, over 3,000 Americans died of the disease each year. Families were overwhelmingly desperate for doctors to find a cure. When one suffered from polio, they generally experienced painful symptoms which included not only fatigue and muscle weakness, but even death. Therefore, when the polio vaccine was introduced by scientist Jonas Salk in 1953, it greatly contributed to Americans in numerous positive ways. Environmentally, the vaccine saved countless young American lives affected by the disease thus decreasing American mortality rates. Socially, the polio vaccine convenienced families who were either directly afflicted
He knew that Polio caused paralysis, and invaded the nervous system. As a result, he wanted to end the greatest epidemic in America at that time. As he began researching, the president of the March of Dimes Foundation, Basal O’Connor, wanted to help Salk create the Polio vaccination. His goal was to fund Salk to find a cure against Paralytic Poliomyelitis, or Polio. Jonas devoted the next 8 years of his life working to develop the vaccine. He finally was able to create the vaccine, using formaldehyde, or a chemical compound. Salk used the killed Polio virus to immunize without being infected, or becoming infected after the injection. Soon after the vaccine was created, they began to test it on monkeys; and then they tested it on children who already had Polio at the Watson Institute. After that trial was done, the testing spread to volunteers who wanted the vaccine; this included Jonas, his wife, and his family. By 1954, national testing began on children between the ages of 6-9. On April 12, 1955, they were able to conclude that the vaccine was safe and effective. Salk became known as a miracle worker, although he remained selfless. Jonas wanted no major payment, or recognition for the creation of the vaccine. In fact, he credited that the vaccine creation was accomplished due to the help of John Enders, a Harvard researcher. Enders was the man
Poliomyelitis (polio) is a disease that attacks the nervous tissue in the spinal cord and the brain stem resulting in paralysis (Document One). Polio is caused by the poliovirus, but it is unknown how this virus is acquired. The virus enters the digestive tract and stays in the intestines for up to eight weeks, and then attacks the lymphatic system, the blood stream and eventually travels to the brain and spine (Document Four). Once it is infected in one’s body, the disease is highly contagious and can be spread through contact of saliva, food, germs, or feces (Document Two). “The poliovirus causes most of its infections in the summer and fall. At one time, summer epidemics of polio were common and greatly feared” (Document Four). This may
Polio, something that can devastate anyone and everyone so very quickly. In 1953, you didn’t know when you could be infected with this life threatening disease.
Through the rise of technological advances in medicine, the vaccine has changed the world for the greater good of the human race. Making a great triumph and virtually eliminating an array of life-threatening diseases, from smallpox to diphtheria, thus adding approximately thirty years to many humans’ life spans. Although, a new complication has arisen, possibly linking neurological digression with this rise of new vaccines. Such a digression has forced parents to exempt their children from receiving vaccinations and brought forth mental anguish affecting the minds of many.
With a substantial amount of preventive healthcare advancements behind them, the American medical community turned its attention to the deadly polio virus plaguing America. From 1937 to 1952, known cases of Americans contracting polio skyrocketed from ten thousand to a staggering figure of roughly fifty-seven thousand cases. Of those cases within that time period, approximately one thousand five hundred deaths as a result of polio were recorded. In the year 1953, The National Foundation for Infantile Paralysis provided the scientist Dr. Jonas Salk with the tools necessary to research, and develop a working vaccine to combat the devastating polio disease. After much trial and error, Dr. Salk was finally able to create what he felt was a successful polio vaccination, and proceeded to conduct a field test. After resounding success, manufacturing instructions for the Salk vaccine were sent to a series of scientific laboratories for immediate production and administration to American children. The disaster that occurred next will forever be known through American medical history as the Cutter Incident (named so after one of the labs that administered the polio vaccine). This medical crisis sent shockwaves throughout America and the medical community, and numerous lawsuits were filed against Cutter Laboratories, resulting in fewer and fewer labs willing to accept contract work in developing vaccines.
Roosevelt became president with infantile paralysis (polio), which was diagnosed in 1921, and the public found out.9 Having the American people's president seem weakened by such a disease but push on through expectations showed that little to nothing was going to get in his way and stop him.10 Including FDR's case, close to 25% of those age 21 and older had paralytic cases by the early 1950s.11 Before the vaccine, there was a peak of about 50,000 cases of polio in 1953.12 Concern of the people was also around it's highest point due to the increasing risk of the horrid disease most feared at this time. Hopes for a solution were still going strong. Friends, family, and even strangers kept prayers for those in need. Anything that could be done was done until the vaccine was established. There were even several hundred thousand children placed in a control study and out of the 749,000, only 33 from the vaccinated group developed paralytic polio.13 In addition to this trial and other performed, and conclusion was drawn stating that the vaccine was 80-90% effective against the paralytic branch of polio.14 Chances for a new beginning were showing up all over with this vaccine, even if it only helped those who haven't been diagnosed
With the last outbreak of Polio in the US being in 1979, many today have no recollection of the terror of this disease. The disease primarily infected children, and there seemed to be no pattern to who succumbed to it. No one could feel safe. Polio as a disease presents such horrors that even those who overcome it once can be plagued by its aftereffects in later life. Before vaccines, single outbreaks could devastate entire communities. One outbreak
Polio had already killed 3,000 people at its peak rate in 1952; sadly, it had already paralyzed thousands of more people (Soylent 1)On April 12, 1955 the polio vaccine developed by Salk was allowed to be used by the public after it had been tested with 1.8 million children (Biography 1). The vaccine had drastically reduced the number of polio cases in children by 90%; 57,000 cases were recorded in 1952 and less than one thousand cases a decade later (Soylent 1). In addition, Jonas Salk later established his own institution for research named Salk Center for Biological Studies in 1963. The institution “remains one of the world's most prestigious facilities for research into AIDS, Alzheimer's disease, Parkinson's
David Oshinsky's 2005 Polio: An American Story, is a history of the fight to eradicate polio in the 20th century. Polio became one of the most, if not THE most, feared diseases of the century due to the influence and example of President Franklin Roosevelt, who was stricken with the disease as an adult in 1921. Owner of a Warm Springs, GA resort dedicated to polio rehabilitation(where he died in 1945), Roosevelt needed to raise funds to keep the resort operational. In 1934, he allowed planners to throw a nationwide series of birthday parties (over 6,000) for him to raise money for the care of polio survivors and for the upkeep of Warm Springs. The success of these parties and recognition that the key to raising money during the Great Depression
Polio is an infectious disease that has killed and paralyzed many people (Birth of Jonas Salk and the death of polio in India). It has taken the lives of