The Pros And Cons Of Liver Conditioning

Satisfactory Essays
We acknowledge several limitations of this study. First, we used only one liver ischemic intervention protocol, i.e. three cycles of 5 min ischemia/5 min reperfusion; thus, it remains unknown whether other liver stimuli strategies can produce cardioprotection. Second, we did not use all three liver ischemic conditioned hearts for immunohistochemical analysis. Rather, we used only RPre+RPost treated hearts, to prove the concept that liver conditioning can inhibit apoptosis in the myocardium. Thus, it remains unknown whether RPre or RPost alone can affect apoptotic protein expression after I/R injury. In addition, the mechanisms by which remote liver conditioning enhance cytoprotective actions seem to be related to MAPK signaling pathways, since
Get Access