The Relationship Between Drug Abuse and Excessive Food Consumption

Cocaine, heroin, methamphetamines, alcohol, opium, tobacco, hypnotics, just to name a few. Addiction is a chronic disease that affects the chemicals in the brain. It dysfunctions the circuits in the brain that deal with memory, reward, sex, motivation, behavior, relationships and emotions all mostly resulting in substance use or other behaviors to fulfill those circuit rewards. This world is in a current addiction epidemic on drugs. Let’s try to understand addiction to make it a little clearer.

Relapses and drug taking are both heavily influenced by similar factors such as the drugs neurochemistry, the user’s history, environment, and dose of the pharmacokinetics. After a period of abstinence or non-use the drugs reinstating is more often an initiation of more than one factor, namely; re-exposure to drug, stress, cues in the environment, priming of the drug to user. In the user’s mind, neurochemical responses are commonly induced through these factors, in that they create a craving by mimicking the drug and this in turn prevents reinstatement and desire to use the drug (McGovern, Xie, Segal, Siembab, & Drake, 2006).

Brain chemistry is a detailed system that helps the brain to interact with the chemicals that moves important around the brain. Brain chemistry changes depending on what substance or how much of the substance is used. These changes can indicate signs of the beginning of an addiction over time if the drug use begins to get worst it can lead to dramatic changes in the brains over all chemistry. This example supports the theory of brain change ”‘when we elevated levels of ΔFosB in the NAc, the mice exhibited behaviors that are considered reliable indicators that exposing people to the same conditions would cause addiction: They showed more sensitivity to the drug (responded to doses one-third those required to produce a response in normal animals), self-administered more drug, and displayed greater drive (or craving) for cocaine (they worked two to three times as hard to get the drug) ().” The opposing side stated this as their disagreement “human psychology is simply the reflection of human neurophysiology. Thus, for instance, although the authors claim that their account of addiction is relatively 'skeptical,' and has less explanatory power than that of their opponents, they nevertheless seem to accept at least the possibility of a complete account, which will only come about as a result of 'further advances in biological and psychological science (Foxcroft, L. J.

It is believed that certain individuals are predisposed or vulnerable to addiction based on biological, psychological and social influences. The euphoric high produced by many addictive substances is the result of overstimulation of the “pleasure center” of the brain. This is the same area that controls emotions, fear, self-control and overall feelings of wellness. The presence of these foreign chemicals creates a response that the brain will crave as soon as it fades. The brain’s chemistry works against its own health, as it rewires its decision making faculties around the primary goal of finding and taking more of the drug” (1). Many people mistakenly believe that psychological addiction is somehow less serious or real than physical addiction. The psychological aspects of addiction are much more challenging to repair and recover from than the physical addiction. Psychological addiction can last for years or even a lifetime.

As results of scientific research, we know that addiction is a disease that affects both the brain and behavior. A disease is an interruption, cessation, or disorder of a body system, or organ structure, or function; according to Stedman’s Medical Dictionary. (Sheff ,2013) cites, the disease od addiction has an etiologic agent, identified by a group of signs and symptoms or consistent anatomic alterations. There are significant changes in the brain. The American Society of Addiction Medicine (ASAM) states that addiction is a primary, chronic disease of brain reward motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristics biological, psychological, social and spiritual manifestations. This is reflected in an individual pathology pursuing reward and /or relief by substance use and other behaviors. (Addiction is characterized by inability to consistently abstain, impairment of behavioral control, craving, diminished recognition of significant problems with one’s behaviors and interpersonal relationships and dysfunctional emotional responses. Like other chronic diseases, addiction often involves cycles of relapse, and remission. Without treatment or engagement in recovery activities, addiction is progressive and can result in disability or premature death. (ASAM Adopted as Policy, February

Is addiction a brain disease? The definition of disease is a disorder in an organism that produces specific signs/symptoms that affects a specific location and isn’t a direct result of any kind of physical injury. Addiction is a compulsive need for any substance or service that can cause a person or organism to form a habit, and is a chronic disease of brain reward and causes dysfunctions in the circuits. Addiction is also characterized by the inability to consistently abstain impairment in behavioral control. The idea that addiction is a brain disease is just about universally accepted among scientist that focus on addiction (Corrigan,2008). However few believe that addiction is not a brain disease because they claim that neural dysfunction is not sufficient for disease. (NCBI, 2012). Some agree that addiction occurs in the brain but should not be considered a brain disease or a disease at all(Lawrence 2013). Substance abuse is the most common addiction that people base their decision upon. These drugs affect the brain and cause different reactions to the rest of the of the body. The types of drugs include: hallucinogens, opioids, sedatives, stimulants, etc. cause different

Addiction is like all behaviours “the business of the brain”. Addictions are compulsive physical and psychological needs from habit-forming sustenances like nicotine, alcohol, and drugs. Being occupied with or involved in such activities, leads a person who uses them again and again to become tolerant and dependent eventually experiencing withdrawal. (Molintas, 2006).

In Carolyn Gregor’s magazine article “8 Fascinating Things We Learned About The Mind in 2015”, she wrote about different people’s chemical abuse , personal lifestyles and environmental choices can affect how the mind reacts to inner workings. Studies found from Script Research Institute may have discovered a new drug which could influence the addiction associated memories in people who are user of meth and other mind altering drugs. This drug will be absorbed into the brain and eventually dissolve past memories which are triggered drug use.

Obesity and drug use both have risk factors that could lead to fatal consequences. According to a study by Volkow et al, (2012) both drug addiction and obesity can be defined as disorders in consistence with the fact that both drugs and food have powerful reinforcing effects by dopamine in the limbic system. Additionally, Volkow’s research uncovered discoveries through brain imaging that common features between drug addiction and obesity are defined with similar brain circuits. The results suggest that both obese and drug addicted individuals suffer from impairments in dopamine pathways, which regulate neuronal systems associated not only with reward sensitivity and incentive motivation, but also with conditioning (memory/learning), impulse control (behavioral inhibition), and

Among the numerous definitions for addiction, there lies yet another to define it from a biochemical perspective. Milkman (1983) defines it as “self-induced changes in neurotransmission that result in social problem behaviors." This definition encompasses the psychological, biochemical and social aspects of addictive processes. It is not limited to substance abuse and can be applied to any activity characterized by compulsion, loss of control and continuation of the substance despite harm. This has helped investigators gain a better understanding of the nature of addiction.

Substance addiction can hugely impact on a person’s thinking, functioning and behaviour. Whilst depressant drugs such as alcohol and opioids slow down your central nervous system (CNS), stimulants such as cocaine or amphetamine increase the activity of the CNS, leading to higher blood pressure, heart rate and increased alertness. Repeated abuse of the substance leads to tolerance and withdrawal, in turn this leads to the user showing signs of irrational behaviour. Another form of substance abuse is hallucinogens; they can cause powerful changes in sensory perceptions. It works by binding to the serotonin receptors, these neurons control visual information and emotions, and this can lead to various effects on the user. Neurobiology can help us understand the reasons for addiction and the effects they have on us. Groman and Jentsch (2012) discuss key issues of differentiating the causes and consequences of addiction through neuroimaging and behavioural research on monkeys, they found that the dysfunction of the dopamine

The complexity of the human brain creates mystery when determining the influence of neurophysiological factors and their role in the process of addiction. There is a proposed relationship between drug addiction and the mesolimbic dopamine system, with the mesolimbic pathway from the ventral tegmental area to the nucleus accumbens considered the ‘reward centre’ of the human brain (Alcohol Rehab, 2011). A release of dopamine is necessary for ‘reward’ which is hypothesised to initiate the addiction cycle by providing positive reinforcement for drug self-administration (Feltenstein & See, 2009). Methamphetamine triggers the release of dopamine from synaptic vesicles which flood the synaptic cleft activating feelings of euphoria, well-being

Recently, the relation has been shown in neural functioning of subjects with addictive-like eating behavior and behavior attributed to substance dependence (Gearhardt, et al., 2011). Specifically, food addiction

Flora is feeling hungry, but she just ate. She walks around trying to forget about the urge to pick up a donut or a random snack from the cupboard. Flora can’t get the food out of her mind. She feels like the food is calling her from the kitchen saying, “Eat me, eat me!” Flora gets up and makes her way to the food. She picks up granola bar, and opens it. The granola bar tastes wonderful and she is content, but then the bar was gone, and a few minutes later she wants another. She feels like she can’t stop eating even after she has eaten a meal. Flora asks why she can’t stop eating. She wonders if she could be addicted, so she turns to the computer and she looks up food addiction. Flora finds that is

An important concept for learning theory is operant conditioning. According to this, the likelihood of a behaviour being expressed again is influenced by punishment or reinforcement. Positive reinforcements are things that act as rewards for certain behaviours and increase the likelihood of the behaviours being performed again. Negative reinforcements take away an unpleasant stimulus and through this again increase the likelihood of a behaviour being repeated. An example of this is withdrawal. Withdrawal is unpleasant and the consumption of the drug that caused the withdrawal leads to the withdrawal symptoms disappearing. Therefore, reinforcing the consumption of the drug. While punishments typically decrease the likelihood of a behaviour occurring, in cases of addiction the punishment often happens a long time after the behaviour, leading people to not make the immediate connection between the behaviour and punishment, and therefore punishment loses its effectiveness (Moss & Dyer, 2010).