The Role of the Lesion Method in the Understanding of Healthy Brain Functions

The core assumption of the validation method is that behaviour is not solely dependent on brain function. According to this framework, behaviour is guided by a combination of physical and psychosocial factors including damage to recent factual memory, eyes and ears, accumulated losses throughout individuals’ lives which could include loved ones, social roles and identity (Parkinson, 2008). The coping mechanisms that individuals have developed throughout the years in times of difficulty also play an important role in the way individuals express themselves through their behaviour

67) The frontal lobes are described as the brain’s “orchestra leader” (Martin, 1998, p. 190), which would place them at the reins of controlling effective behaviour. Damage to the frontal lobes encompasses a wide range of symptoms including deficits in executive functioning, changes in personality, emotional expression and social interaction. This includes apathy and lack of spontaneity, inability to plan and modify the sequencing of behaviour and inappropriate behaviour. 2

Neurologist Antonio Damasio has written significantly on Gage and other patients that he studied on with similar injuries. Damasio viewed Gage's case as playing a crucial role in the history of neuroscience, and stated that Gage's story "was the historical beginnings of the study of the biological basis of behavior". Gage's case inspired the development of frontal lobotomy, which now is a psychosurgical procedure that leads to emotional response and personality traits. On the other hand, historical analysis doesn't support this claim because Gage's injury didn't have enough influence on the development of this practice.

That is the reason why Gage’s case is so important for the field of psychology because it is a real proof of so many questions that scientists had for several years and go in back for information made them realized that they have a real life proof of the theories scientists used to have about the brain. It is a case that changed psychology in several ways and it also helped scientists and researchers answer their questions about the brain and the connection with personality change. And that it was Gage’s case about, his personality changed because of this

2012.). These symptoms are a result of trauma to the lobes that are responsible for an individual’s speech, coordination, memory, and motor control. Each brain structure is vital in how an individual functions and perceives the world; when this structure is damaged, even temporarily, the functions of the structures are delayed. However, long-term issues from damage to the brain are extensively detrimental its function. While some may experience impulsivity, violent behavior, emotional/social withdrawal, and memory issues, others may experience language disturbances and sensory disorders (“Psychological Sequelae: Postconcussion, Frontal and Temporal Lobe Syndromes”. 2012.). These long term issues are commonly due to the persistent damage to the frontal and temporal parts of the

The brain can be affected by damage and cause behavior to be expressed differently in every person. Events such as a car crash or childhood abuse can affect brain development and function. Damage to certain areas of the brain can have a variety of effects. The hippocampus controls emotions and is associated with memory, and the frontal lobe is a brain cortex that controls motor functions, problem solving, memory, language, judgments, social and sexual behavior and impulse. When the frontal lobe or hippocampus is affected, a person’s emotion can be out of their control. In criminal cases, brain damage can affect the sentencing of a violent criminal, but to what extent should these abnormalities play a role in their conviction? Much research has been conducted in order to determine the effect that brain abnormalities should have on the conviction of violent criminals. A psychiatrist at New York University, Dr. Lewis, has conducted a study on death-row inmates, how their brains work and what affect the damage had on their conviction. By doing so Dr. Lewis paved the way for other researchers, such as Kent Kiehl and Jonathan H. Pincus to study the brains of violent criminals looking for a answer as to whether or not these criminals should be incarcerated. Over time research has been conducted focusing on mental illnesses and brain damage as the cause of violent acts instead of it being just premeditated murder. Many believe brain damage or mental illness should have no affect on

The right and left frontal lobes at the front of the brain are involved in mood, social behaviour, attention, judgement, planning and self-control. Damage can lead to reduced intellectual abilities and changes in personality, emotion and behaviour.

Overall, this article describes numerous cases of people’s personality and behavior being drastically affected by various forms of brain damage, particularly to the frontal lobe. This is consistent with what we have learned about Phineas Gage and his dramatically changed personality. As such, the author, David Eagleman, concludes that humans are not really “free” and that we are all products of our brains’ physical state, meaning that the notion of all humans being equal in their decisions is fundamentally flawed. He therefore proposes modifying the criminal justice system so that sentencing is customized more for the particular offender, taking into account the functionality of the criminal’s brain,

The trend of neurobiology and physiology predicting and causing behavioris not a new fact. So many illnesses and diseases are now attributed to biological mechanisms. A recent article in Newsweek comments on how those in the field of psychology and neuroscience are beginning to stress the fact that certain brain mechanisms account for mental illnesses and particular behaviors. Doctors seem to blame their patients peculiarities on a biologically based mental illness, rather then seeing them as individual responses to lifes circumstances (Begley 1998). It then becomes more common to prescribe drugs to alleviate the symptoms rather than understanding the behavior. Two recent developments have

Due to its primary role in processing memory and emotional reactions, over the last decade and a half psychologists have been linking the amygdala to psychopathy. It is involved in aversive conditioning and instrumental learning and is thus involved in all the processes that, when impaired, produce the same functional impairments displayed by psychopaths. Two famous studies conducted by Tiihonen and Kiehl respectively have confirmed this. Tiihonen used a volumetric MRI to test and confirm the positive correlation between low amygdaloid volume and a high degree of psychopathy in violent criminals (measured by the Hare checklist-revised) while Kiehl used a functional MRI to prove reduced amygdala response during an emotional memory task in individuals who scored high on the Hare checklist-revised. However, both these studies along with numerous others were conducted using violent offenders as subjects rather than individuals with psychopathy. Although many psychopaths do exhibit violent tendencies, not all violent offenders are necessarily psychopaths. A study conducted by Raine is one of the few that did focus only on individuals exhibiting psychopathy. In his study Raine was able to show reduced prefrontal grey matter in his test subjects. Unfortunately though, he was unable to differentiate between grey matter in different regions of the prefrontal cortex. It is however clear that there is one region of the frontal cortex that could be

Neuropsychology is the study of brain-behavior relationships (Barkley, 1983). It is the scientific study of the association between the different structures and physiological processes of the nervous system and the behavior of organisms (Barkley, 1983). The focus of this particular field in psychology is not just pertaining to humans as research on infrahumans consistently provides simple scientific information and data from which research ideas on humans will be drawn/ concluded from (Barkley, 1983). For example, research that was conducted on rats involved giving amphetamines to the rats with given closed head injuries yielded the option of exploring the use of stimulant drugs in helping the recovery of adults and children that have experienced accidental closed head trauma (Barkley, 1983). The field includes the study of developmental changes of the nervous system and it’s behavioral parallels as well as the effects of experimental and also accidental changes of the nervous system on the behavior of an individual (Barkley, 1983).

In order to understand why people act in antisocial ways, one needs to pinpoint which area of the brain controls social behavior. The prefrontal cortex has been thought to have something to do with control of social behavior ever since Phineas Gage's famous accident in 1848 (1). Phineas Gage was a

In contrast, a technique favoured by cognitive neuropsychologists is neurological case studies. These are reports on individuals who have suffered damage to the nervous system. Researchers can observe the behaviour of participants and interpret how this has been affected by their brain injury. However, the conclusions that can be taken from such studies are also limited, especially when they involve a single subject, (Payne and Wenger, 1982).

The Anatomy of Violence presents the latest findings in the field of biological psychology and human behavior, focusing on brain chemistry, as it relates to human behavior, and offers great insight on how brains of those who commit acts of violence or crime differ from those who do not. Mr. Raine provides solid scientific data regarding the ways in which brain chemistry differs and how injuries can alter personality using medical MRI and fMRI and various neurotransmitter studies. A clear connection between human biology and behavior emerges, bringing

Neuroimaging is a multidiscipline science and experts from the field of psychology, statistics, physics and physiology all contribute to its further development (Poldrack et al., 2007). In the last 20 years the imaging techniques developed from single proton emission tomography (SPET) to positron emission tomography (PET) and finally to functional magnetic resonance imaging (fMRI) (Page, 2006). Their applications are numerous in experimental and cognitive psychology. However, at one level they can constitute another dependent variable (brain activity) as a response to an independent variable (stimulus manipulation) and at the other level, understanding the structure and processes of the brain can shed light on ‘normal’ cognitive