The Signaling Pathways That Control Stem Cell Fate Essay

Many of us have all heard the saying that a “lizard can lose its tail,” and bizarrely enough it will grow back. This was always considered impossible for humans, an idea belonging in the realm of science fiction, but now the regeneration of tissue is an extremely realistic possibility. Despite some opinions, this process does not happen naturally, or take place as cinematically as one might imagine. Over the past decade, there have been major advances in regenerative medicine, commonly known as stem cell research. Stem cells are undifferentiated cells within the body that have the capability to specialize into any tissue. They are most commonly found in cord blood, bone marrow, organ donations, placenta, and embryos . Stem cells are seen by some as a new miracle treatment, encouraging many countries to invest in their research.

Embryonic cells should be allowed to be used because of the medical benefits they provide. They can be used to cure diseases such as Parkinson’s disease, diabetes, traumatic spinal cord injury, Duchenne’s muscular dystrophy, heart disease, and even vision and hearing loss (nih.gov 2009). There is no problem using them for medical purposes and it is not immoral to use them for this reason. Embryonic cells have the potential to save lives. Therefore, the usage of embryonic cells outweighs the ethical issues.

Stem cells are basically the building blocks of life. Some type of these cells can be engineered into any type of cell in the human body. There are three types of stem cells currently. Adult or somatic stem “cells can generate replacements for bone and muscle cells that are lost through injury, disease or normal wear and tear.” Another type of stem cells are embryonic stem cells. Embryonic stem cells “are “starter cells” that can be coaxed into becoming any of the specialized cells of the body, meaning they are “pluripotent.” The final type of stem cells are induced-pluripotent stem cells. Induced pluripotent stem cells “are adult stem cells that have been genetically altered to behave like embryonic stem cells”(National Institute of Health). Due to the advancement in medical technology scientists and doctors alike are now able to use stem cells for a variety of reasons like research and also in patient care. The benefits of this research can lead to the cure of diseases like diabetes, some cancers, and even neurodegenerative diseases like Parkinson’s Disease and spinal cord injuries. The controversy behind stem cells lie from where these stem cells come from. The source of stem cells are plentiful. Some stem cells can come from human embryos that are a few days old. Stem cells can also be engineered in a laboratory setting using the cells from human embryos. Also there are certain stem cells that can be harvested from adults and

In the past two decades, many technological and scientific advances have been made in order to make life easier for many people who suffer from cancer, disease and sickness. Among these advances there is something revolutionary called stem cells. Stem cells can help restore and regenerate almost all parts of the human body such as the heart, kidney, liver, and many other organs. Although stem cells offer a lot, there are many views against and for stem cells, and among these views lies the debate of whether stem cells should be legalized or not (NIH 2). Stem cells offer exciting new opportunities in the field of science such as regenerating human body parts, but many people are still debating whether or not the use of stem cells is

Christopher Reeve, better known as superman, was not only an actor, but also an athlete and an adventurer. On two separate occasions, he flew an airplane sole across the Atlantic Ocean. On Memorial Day weekend in 1995, Chris rode his horse, Buck, to the starting box of a cross-country race in Virginia. Chris had trained and raced horses for almost ten years, so he felt the course ahead of him would be easy. But what Chris did not see coming was just as he and Buck approached the third jump, Buck would come to a sudden stop, sending Chris over the jump. He landed directing on his head, fracturing two vertebrae in his neck. From that day on, he was completely paralyzed. At the time, there was no known treatment, no medication, and no surgery to fix his damaged spine. For the rest of his days, Chris raised money and awareness for research into spinal cord injuries. One of the topics he pushed for was embryonic stem cell research. Christopher Reeve died on October 10th, 2004, never fulfilling his goal to walk again. But if he had gotten the support and funding for stem cell research, his story might have ended differently. Embryonic stem cell research should be funded in the U.S because it could lead to the treatment to many diseases, there are other sources of stem cells, but they are limited to their use, and the eight-celled blastocysts cannot grow any further to form a baby, so it is not harming living human beings.

This article discusses the successful use of experimental stem cell treatments within a variety of clinical trials, discussing the two main types of stem cells, embryonic and adult. The article draws on research published by the Massachusetts Family Institute, "a pro-life group that is opposed to the use of embryonic stem cells" to illustrate the successful use of adult stem cells to reverse the effects of, or cure entirely, a number of severe diseases such as Crohn's disease and lupus. It also references a report by Medical Use Today which highlights encouraging experiments with embryonic stem cells that appear capable of reversing paralysis caused by spinal injuries. Written for religious audience tolerant of scientific advancements, the article focuses almost entirely on the positive aspects of experimental stem cell research, and cites studies that support its preconceptions on the subject. The author, a former "instrument development and computer science professional," possesses a scientific background which informs the construction of the article's overall argument. I found this article by searching the Ontartio Consultants on Religious Tolerance essay database, found at ReligiousTolerance.org.

Embryonic stem cells have the ability to grow into any type of cell that your body contains and can potentially aid in curing diseases and or repair many essential things in your body such as a kidney or a lung. This sounds like an extremely favorable advantage to medical advancements but this subject does summon some intense debates on where the stem cells come from. Embryonic meaning that it comes from the embryo veers many people’s opinion to totally protest any use of embryonic stem cells. Opposing abortions and the use of embryonic stem cells go hand in hand. Many people are just not ready for the responsibility of having a child so they take matters into their own hands and many consider having an abortion. In the end everyone takes their own decision and they fit it to what they feel is best for their lives. Many people may see an abortion as killing an innocent life but people make their own decisions and no one can stop them. Abortions are a solution to unprepared individuals that can not handle the responsibility of having a child; why not use the cells from the procedure to save a life. Children are wonderful gifts but some people are just not ready to take up the responsibility of raising that gift so they can use that gift to help another needy life.

Stem cells are cells that are found throughout the human body. They reproduce over a long period of time without changing. Stem cells can produce specialized cells, such as brain, muscle or lung cells. Stem cells in the last few years have recently made a big debut because medical professionals have discovered so many unique qualities to stem cells. They are on the cutting edge of medicine because of all their uses and the qualities that make them so unique from any other cell in the body. Stem cells have the power to make so many breakthroughs in the medical world. Medical researchers have all ready found so many ways that stem cells can be used for the better of so many people. Genes play an important role in determining what genetic traits or mutations we receive. Researching stem cells can help determine this. Stem cell research is useful for learning many things about human development and about how the body has the power to repair itself. Researchers are finding new ways each day that stem cells can be used and the possibilities that they find for stem cells could be endless. A few ways they can be used to treat diseases, be used as graphs for burn victims or surgical use, and even to correct birth defects. The pros of stem cells are limitless.

Imagine a child, no more than six years old, with a failing liver. There is no way for that child to receive a functional liver because of the waiting list for organs. That child will almost certainly die waiting for that liver, and never get close to the top of the list. The main reason for this is quite simple: there are not nearly enough organs available for transplant to save the people that need them. Because the research of stem cells isn’t developed or funded well enough for functional organs to be made, many people will die waiting for the organs. But, if funding and support was provided, lives would be saved instead of lost. Stem cells should be used in more clinical

With the advent of a wide variety of scientific advances in the medical field, especially those improvements in health-related fields, the quality of life for the earth’s inhabitants has improved greatly over the past century. Scientists continue to improve upon current knowledge and expand the field of medicine. Over the past few years, scientists have performed significant research pertaining to the study of stem cells. Many researchers see potential in the manipulation of stem cells - possible treatments for currently incurable diseases such as Alzheimer’s and Parkinson’s (Goldstein). With these new discoveries, though, questions as to the morality of such practices arise. While few find an

Stem Cell Research: Should we continue to allow scientists to create new embryonic stem cell lines?

and plenty of other degenerative diseases while the cure lies in our hands? After James Thompson, a developmental biologist, reported that he had derived the first human embryonic stem cell line (Thomson), the potential of curing degenerative diseases was revealed. Ph.D. holder and deputy director of FDA’s office of Cellular, Tissue and Gene Therapies, Stephanie Simek, explains that stem cells are unspecialized cells (qtd. in “FDA Warns About Stem Cell Claims”). In other words, since they are unspecialized cells, they can “…generate lots of cells and, under the right conditions, become one of the many cell types

Stem cells are undifferentiated cells that have the potential to differentiate into specialized cells that make up various organs in our body. Intriguingly, if the stem cells are given the right conditions, they can divide, differentiate and self-organize to form an organ by itself. Organs formed in this manner are called organoids. Specifically, Organoids are structures resembling organs, generated from embryonic stem cells in a three-dimensional culture system similar to in vivo. However, these structures need to possess specific characteristics in order to be termed as organoids; must contain multiple cell types of the organ it models (organ specific), must exhibit some specific functions of that organ and the cells should be spastically organized to mimic the targeted organ. Organoids have the ability to recapitulate the organ by self organizing itself. Self-organizing is governed by the combination of sorting out and fate specification and also, due to a growing movement away from two-dimensional culture. Different organoids can be generated different organs. Although, the generation of 3D organoids is a relatively new concept, it holds the potential to make promising changes in the field of medicine.

This paper will be divided up into three main sections: what are stem cells and the

I’ve been slouching on this stool for what seemed like ages. Regarding my cell carelessly, I shook my head at my stupidity. As if anything was actually gonna change since the last 50 times I looked; gray walls and floors, and a mattress with a thin cloth blanket lying wrinkled on top. The only thing that doesn’t stay the same is the spiders that roam throughout the cell as they please- I envy them.