The Speech On Parkinson 's Disease Essay

Neurology is one of the most unexplored fields in medicine; however, more recently there has been a spike in the amount of research being done in this specialty. This is because people are becoming more interested in neuroscience, including myself. I attended a pre-medical vocational high school, which exposed me to a greater amount of knowledge pertaining to the basics of anatomy and physiology, along with hands-on opportunities in a medical setting. It was here where I realized that I wanted to pursue a career in medicine; however, due to the fact medical field is very broad, I had no set specialty. This changed when I was exposed to the cruel manifestations of Parkinson’s Disease. During, sophomore year of high school, my grandfather passed away due to complications of Parkinson’s Disease. The way that a neurodegenerative disease was able to overtake a person in the manner that it did was shocking, and while it brought me great grief initially, it later intrigued me. I took up an interest in neuroscience and began to do my own research which culminated in various projects and applications throughout the remainder of my time in high school. These experiences have culminated in my decision to work toward a Cell Biology and

As I stepped into the mud room to take off my bright pink rainboots, I knew something was not normal. As I glided onto the sleek wood floors to grab a crunchy after-school snack, I hear my mom descend down the carpeted stairs slowly, becoming aware that this will not be a normal “how was your day at school” conversation. I raced to the cabinet to grab my fix of Goldfish and I sat down on the floor to get a little snuggle time with my dog before my world was turned upside-down.

Parkinson disease (PD) is one of the most common neurologic disorders. and it affects approximately 1% of individuals older than 60 years old. Parkinson’s disease is a condition that progresses slowly by treatment. In addition, loss of pigmented dopaminergic neurons of the substantianigra pars compacta and the presence of Lewy bodies and Lewyneurites are the two major neuropathologic findings in Parkinson disease (Hauser, 2016).

If you eat unhealthy, fatty foods your whole life, you have a higher risk of developing diabetes, cardiovascular disease, or arteriosclerosis. If you have unprotected sex, you may contract a sexually transmitted disease, such as syphilis, gonorrhea, or HIV/AIDS. But, Parkinson’s doesn’t racially discriminate, nor does it care if someone is wealthy, poor, educated, non-educated, male or female. Anyone can develop Parkinson’s disease. The disease begins in the brain, our most intricate, delicate organ, whose complexity is still not entirely understood, even with today’s technology and experts. The brain intrigues me. I find myself curious about brain

I whisper to myself as I approach the patient. I need to notice every detail. I must not miss a single word or a single movement. Each detail is a clue and each clue is imperative to solve the case and find the diagnosis. I am Sherlock Holmes and this is my mystery to solve. I take a deep breath.

J.N., a 65-year-old Caucasian female with a history of anxiety and depression, presents for diagnostic testing at Saint Mary Medical Center in Hobart, Indiana to confirm or deny a diagnosis of Parkinson’s Disease, after presenting with recent onset of upper extremity tremor affecting both sides and facial masking. Patient history also includes bradykinesia, restlessness, fatigue, muscle weakness, and poor balance and coordination, all of which are common in a diagnosis of Parkinson’s Disease. J.N. was referred to the Neurology Department of Saint Mary Medical Center after a routine appointment with her Cardiologist, who noted the recent onset of additional signs and symptoms. J.N. is my mother and my inspiration for this assignment.

Michael J. Fox was born on June 9th 1961 in Edmonton, the capital of the Canadian providence, Alberta. Fox moved many times throughout his childhood due his father, William Fox, being in the military. Eventually Fox’s family ended up in Burnaby, British Columbia, where they established a permanent residence. (Michael J. Fox Foundation)

Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.

Parkinson's is a disease that may happen in younger people, but the risk mainly increases

Situation- Devina has come in to hear her test results; from her car accident that she had last week, little does she know that she is going to be diagnosed with Parkinson’s disease…

Parkinson’s Disease is a long-term progressive neurodegenerative disease consisting of motor system impairment, neuropsychiatric, and nonmotor features. The disease is characterized by the following key clinical features: bradykinesia, resting tremor, postural instability, and rigidity. These symptoms are due to the diminishing of dopamine in the nigrostriatal pathway and substantia nigra, which causes inhibition of the thalamus decreasing excitatory input to the motor cortex.1 Along with the key manifestations an individual with Parkinson’s Disease will experience problems associated with the disease or the antiparkinson medications. These co-occurring problems are hallucinations, dementia, daytime sleepiness, fatigue, depression, and pyschosis.2 Psychosis is a common problem in Parkinson’s Disease, and is characterized by paranoid delusions and hallucinations that are visual in nature.2 Risk factors for psychosis consists of advancing age, dementia, sleep disorders, and high doses of antiparkinson drugs.1

Parkinson’s Disease is known as one of the most common progressive and chronic neurodegenerative disorders. It belongs to a group of conditions known as movement disorders. Parkinson disease is a component of hypokinetic disorder because it causes a decreased in bodily movement. It affects people who are usually over the age of 50. It can impair an individual motor as well as non-motor function. Some of the primary symptoms of Parkinson’s disease are characterized by tremors or trembling in hands, legs and arms. In early symptoms the tremor can be unilateral, appearing in one side of body but progression in the disease can cause it to spread to both sides; rigidity or a resistant to movement affects most people with Parkinson’s disease,

Parkinson’s Disease and Action of Drugs on Movement Introduction: Parkinson’s disease is a neurological disorder that seriously impairs motor function, with people afflicted with this condition exhibiting akinesia, muscle rigidity and having a tremor at rest. It is accepted that the loss of motor function is brought upon by the progressive degeneration of nigrostriatal dopamine neurons, which leads to a corresponding loss of dopamine in the caudate/putamen part of the basal ganglia, which is accepted as the main receiving area in motor circuits. Information coming to it from the cortex and thalamus is processed and channeled to the pallidum and to the substantia nigra reticular. There are two

disorder that affects 10 million people worldwide. It is characterized by progressive loss of midbrain dopamine neurons in the substantia nigra pars compacta. Neither the molecular mechanism that underlies the pathogenesis of Parkinson’s is fully understood nor preventative and effective treatment is available. In the past few years, epigenetic mechanisms have emerged as potential mediators of environmental factors which cause abnormal epigenetic modifications which have been detected in PD. The term Epigenetics, refers to reversible heritable alterations in gene expression without any changes in DNA sequence. Fundamental mechanism of epigenetic regulation is mainly chromatin modification which is divided into several categories including DNA methylation, histone modification, histone variant, and non-coding RNA. This assignment discusses on recent studies on how epigenetic dysregulation, which modulates gene expression, plays key role in

Parkinson disease (PD) is a progressive neurodegenerative disorder characterized mainly by physical and psychological disabilities. This disorder was named after James Parkinson, an English physician who first described it as shaking palsy in 1817 (Goetz, Factr, and Weiner, 2002). Jean- Martin Charcot, who was a French neurologist, then progressed and further refined the description of the disease and identified other clinical features of PD (Goetz, Factr, and Weiner, 2002). PD involves the loss of cells that produce the neurotransmitter dopamine in a part of the brain stem called the substansia nigra, which results in several signs and symptoms (Byrd, Marks, and Starr, 2000). It is manifested clinically by tremor,