The Successful Treatment Of Malaria

Brian, G, Y., Greenwood, D, A., Fidock, Dennis, E, K., Stefan, H, I. Kappe, P., Alonso, L., Frank, H and Collins, P (2008) “Malaria progress and prospects for eradication.” Journal Clinical Investiment. 118: 1266-1276.

Malaria is a disease that affects nearly 600 million people and causes more than a million deaths a year, the most coming from children under five. This disease is regularly found in more than 100 countries around the world and affects 40% of the world’s population. It is most commonly transmitted by an infected Anopheles mosquito. The most deadly form of malaria is known as Plasmodium falciparum because almost all deaths from malaria are caused by this specific one. Some of the symptoms that are affiliated with this strand of malaria are the destruction of red blood cells along with complications with the kidneys, lungs, and brain. In more serious cases, it can cause permanent neurological effects and even death. As the Nobel Assembly said at the announcement of the Nobel Prize in Physiology or Medicine, “Diseases caused by parasites have plagued humankind for a millennium and constitute a major global health problem. In particular, parasitic diseases affect the world’s poorest populations and represent a huge barrier to improving human health and wellbeing”. Youyou Tu, one of the winners of the prize, discovered Artemisinin, “a drug that has significantly reduced the mortality rates for patients suffering from malaria by killing the malaria parasites an early stage of their development.”

The symptoms vary because patients are diagnosed with having either uncomplicated or severe malaria. This is due to the fact that different kinds of malaria range in severity. For instance, ,P. falciparum and P. knowlesi infections can cause rapidly progressive severe illness and lead to death death while the other species, P. malariae, P. vivax, or P. ovale are less likely to cause such severe manifestations. Furthermore, P. vivax and P. ovale infections also require treatment for the hypnozoite forms that remain dormant in the liver and can cause a relapsing infection. Finally, P. falciparum and P. vivax species have varying drug resistance patterns in different geographic regions. For P. falciparum and P. knowlesi infections, the urgent initiation of appropriate therapy is especially

There have been many attempts at preventing malaria, none of which have been very successful. These have usually involved protecting human beings from mosquitoes, the dreaded carriers

Malaria is considered one of the most serious and life-threatening public health problems in the world. According to World Health Organization, more than 3 billion people live in areas classified as being at risk from malaria, with nearly 200 million cases.1 Approximately, 750,000 deaths occur every year, primarily among children, due to malaria and its complications.1 Children less than 5 years of age are more vulnerable to be affected by malaria.2 In 2015, about 438,000 malaria deaths were reported, of which estimated 69% were children under 5 years of age.2

In the seventeenth century a group of Jesuits brought back tree back that had quinine in it from Peru. This proved to cure malaria and was a major step in malaria treatment. The complexity of the malaria parasite is astounding, as it has six separate cycles in which half occur in the mosquito and half occur in the human body. Due to this extremely complex life cycle, there is no easy way out to target one point, and to fully eradicate malaria the entire global population would have to be on anti-malarial pills for the entire life cycle of a mosquito.

"Malaria Cure." Centers for Disease Control and Prevention. CDC, n.d. Web. 10 Dec. 2015. .

During the first decade of the 21st century, malaria-related morbidity and mortality declined dramatically in many Kilifi, but not in all, parts of sub-Saharan Africa. Insecticide-treated bednets (ITNs), rapid economic development of the continent and the introduction of artemisinin-containing combinations as first-line treatment for uncomplicated malaria played important in the controlling malaria.

According to the Malaria Vaccine Institute, almost 600 million people suffer from malaria each year, and more than one million people die from this disease every year, the most deaths come from children younger than five. Malaria is endemic to over 100 countries in Africa, Asia, Latin America, the Middle East, and the South Pacific, around 40% of the world population. Malaria is caused by a parasite that is transferred by the bite of an infected female Anopheles mosquito. The most deadly form of malaria is known as Plasmodium falciparum because almost all deaths from malaria are caused by this specific one. In addition to being the deadliest form of malaria, Plasmodium falciparum destroys red blood cells along with causing complications with the kidneys, lungs, and brain. In more serious cases, it can cause permanent neurological effects and even death. As the Nobel Assembly said at the announcement of the Nobel Prize in Physiology or Medicine, “Diseases caused by parasites have plagued humankind for a millennium and constitute a major global health problem. In particular, parasitic diseases affect the world’s poorest populations and represent a huge barrier to improving human health and wellbeing”. Youyou Tu, one of the winners of the prize, discovered Artemisinin, a drug that has significantly reduced the mortality rates for patients suffering from malaria by killing the malaria parasites an early stage of their development.

Around 300-600 million people suffer from malaria each year, and over one million people die from this disease every year, mostly children younger than five. This disease is endemic to over 100 countries in Africa, Asia, Latin America, the Middle East, and the South Pacific, almost 40% of the world population. Malaria is caused by a parasite that is transferred by the bite of an infected female Anopheles mosquito. The most deadly form of malaria is known as Plasmodium falciparum because almost all deaths from malaria are caused by this specific one. In addition to being the deadliest form of malaria, Plasmodium falciparum destroys red blood cells along with causing complications with the kidneys, lungs, and brain. In more serious cases, it can cause permanent neurological effects, and even death. As the Nobel Assembly said at the announcement of the Nobel Prize in Physiology or Medicine, “Diseases caused by parasites have plagued humankind for a millennia and constitute a major global health problem. In particular, parasitic diseases affect the world’s poorest populations and represent a huge barrier to improving human health and wellbeing”. Youyou Tu, one of the winners of the prize, discovered Artemisinin, a drug that has significantly reduced the mortality rates for patients suffering from malaria by killing the malaria parasites an early stage of their development.

Malaria has been spread by various factors, from contaminated blood transfusion to mosquitos, being the leading carrier of malaria. It can have damaging effect on the human body, and with it constantly changing, the malaria protozoa becomes harder for doctors to treat. Malaria, causing as 1.2 million deaths in 2011, has had a global impact “(Mcneil 1). It is still heavily impacts people in many tropical areas (“Disease” 202). New natural remedies have been tested to attempt to combat malaria (Avasthi 1).Malaria can have a deadly impact on all types of people, including pregnant women (Gomes 1). The malaria parasite is changing to resist treatments, and doctors are researching how to defeat it (Avasthi 1). Malaria is from genus plasmodium, which

According to the health and environment, Malaria is a universal contagious disease and also a tremendous social complication all around the world, especially in South Asia, and Africa. Approximately, 3 billion of the community are in danger of infection in 109 regions. Every year, there is a prediction of 250 million compacts of miasm prominent to 1 million annihilations, particularly adolescents under 5 years old. The structure that causes the greatest unhealthy form of paludism is a imperceptible parasite that is known as the “Plasmodium falciparum”.

falciparum is by far the deadliest and causes the most severe symptoms. This species is most prevalent in Africa and is the single leading cause of concern in terms of morbidity and mortality. The other three Plasmodium spp., vivax, ovale and malariae may lead to a much milder form of malaria that is easily treated. For the remainder of this article, the main focus will be on malaria cause by P. falciparum.

Medical treatment for malaria is available and the disease is curable if promptly diagnosed and treated well. This is crucial because those who have malaria parasites available for mosquitoes to feed on are perpetuating the spread of the disease. However, if these people are treated with the appropriate drugs, the parasites disappear from their bloodstream. This helps to reduce the transmission of the disease. Unfortunately, not everyone is responsive to drug treatments for malaria and thus a variety of alternatives need to be available. Not everyone with malaria parasites in their bloodstream shows the symptoms of malaria and the disease itself is becoming resistant to some of the drugs used to treat

A prospective cross-sectional hospital-based study of 125 adult falciparum malaria patients using simple, direct, standardized questionnaire including history, lab investigations and neurological examination from January to December 2014.