The Use Of CRISPR Technology

Humans have been genetically engineering organisms for nearly 10,000 years using traditional methods of modification—among these methods include selective breeding and crossbreeding. Though effective, these methods were unreliable and were only able to change certain traits. A lack of control over our genetic material proved to be a clear hindrance to our species; when harnessed, advancements in other fields of knowledge would be immeasurable. Once seen as an impossible task, scientists have been able to exploit genes and take control of them. CRISPR-Cas9 is a system that allows scientists to cleave off sections of DNA and artificially modify them by inserting a mutation into the place of the old DNA. This is exceptionally precise, whilst

With modern technology comes the breakthrough of the decade by altering the human genes. This altering gene invention is called CRISPR/Cas9. However, this invention in the beginning stages of altering genes, began with rats until perfection. The process began early with the embryo stages to edit the genes. With the introduction of CRISPR surrounds a lot of controversy. Some people believe editing genes is playing with the hands of God and refuse to believe in CRISPR. With the article, “Let’s Hit Pause Before Altering Humankind”, by David Baltimore believes CRISPR is a tool with no good intentions. With this information the article should not be published with being against CRISPR.

CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, referring to the repeating DNA sequences found in the genomes of microorganisms. CRISPR technology allows scientists to make precise changes in genes by splicing and replacing these DNA sequences with new ones. Through these changes, the biology of the cell is altered and possibly affects the health of an organism. The possibilities are endless as this offers opportunities in curing deadly diseases, modifying genes, and changing humanity as we know it. Although bioengineering has been around since the 1960s, CRISPR is significant because of the comparative low costs and the ease of the procedure to

CRISPR Cas-9 is a system that changes genes and shows a further promise for treatment for Duchenne Muscular Dystrophy (DMD). Doing this will hopefully avoid ethical dilemmas. DMD effects nearly 1 in 5,600-7,700 people between the ages of 5 and 24 for males in the U. S. CRISPR stands for “Clustered Regularly Interspaced Short Palindromic Repeats”. These are DNA segments found in microorganisms that repeat itself in open spaces. CRISPR attacks any virus that comes into your body and cuts the strand of virus on the DNA out. Researchers have tried to cure DMD in mice by getting therapy through the back of the eye, one of the ways CRISPR therapy works, which seems to work best.

Modifying genomes hasn’t been perfected, and is far too great of a risk to use on society. No one knows what could happen to the population after man starts messing with mother nature. Scientists who are trying to destroy genetic diseases could create new problems or end up killing its test subjects later down the line. The possibilities for disasters are endless. People also claim that modifying humans is the fastest and most efficient way to getting rid of physical and mental health problems, but according to Molecular biologist Ellen Jorgensen, Using CRISPR isn’t what people see it to be. Ellen explains that using CRISPR is not actually easy at all. To use the technology, damaging the gene is crucial. Once the gene is damaged, and the cells start to repair, scientists can then manipulate the cells to repair the way they want it to, and not naturally. This is a complicated process, and it not in any way

Human gene editing has long been controversial topic; however, precise techniques that accomplish this feat have only recently been discovered. According to the Welcome Genome Campus in the UK, the most versatile and simplest technique, called CRISPR-Cas9, allows scientists to cut, alter, or add to sections of the DNA sequence of living organisms (“What Is CRISPR-Cas9?”). This astonishing technology has nearly endless applications, including the potential to eradicate genetic diseases in humans that currently have no cure. This could have vast implications for people who suffer with disease and the economy of the region in which they live, but the technology has yet to be commercialized. The

CRISPR Cas9 technology should be used to modify human and embryonic DNA because if we have the technology of CRISPR Cas9 and all of the advantages it entails to help people who want to have healthy children and to stop the inheritance of deadly genetic diseases, then we should. I believe the evidence supports my claim because CRISPR has so many advantages in knocking out the diseased gene to stop the passing down of the diseased gene. Although it is still in the research stage, the number of risks including the off target mutations and the generation of mosaics have been very low and close to none which helps the argument against CRISPR of it being unsafe and unexpected. The evidence states

CRISPR/Cas9 DNA editing system is a prokaryotic immune system that becomes resistant to foreign genetics such as plasmids. CRISPR stands for Clustered Regularly-Interspaced Short Palindromic Repeats, which are prokaryotic DNA strands that have a short repetition base sequence. Cas9 is a nuclease enzyme that is used to cut into DNA strands that are associated with CRISPR type II. CRISPR/Cas9 system has several advantages when using this technology in the biological and biomedical sciences. It also has a few disadvantages that cause concerns when using this system in the medicine field. However, before all of this can be discussed, a depth of what CRISPR/Cas9 is and where it comes from and why is it important to the biology field.

Imagine a world where we can control genetics. What if we had the opportunity to eliminate all genetic diseases in just a few steps. Imagine a society where anyone could flip through a catalog to shop for traits to “design” their child. This may seem a little far fetched, however this imagined world may soon become possible through the rapid advancing development of genetic engineering. New and advanced technology has finally made it possible to access and hack the human genome. New gene editing technology called CRISPR Cas-9 has completely transformed the biomedical field. CRISPR Cas-9 is cheap, precise, efficient and ultimately works on all living organisms. Advanced genetic technology that have allowed us to genetically modify our food and clone sheep, may one day give parents the option to modify their own children. However the idea of one day creating “designer babies” sparks great controversy.

Even though it was discovered in 1987 by a research team at Osaka University, the true power of CRISPR, which functions as an adaptive bacteria immune defense, was not realized until the completion of the Human Genome Project in the early 2000’s (Carroll and Zhou 63-64). There are only two components of CRISPR, a guide RNA sequence (gRNA) and a Cas9 endonuclease protein. When the gRNA binds to its matching template DNA sequence, the Cas9 protein cuts the template DNA sequence resulting in the inactivation of that specific gene (Hille and Charpentier 3). In addition, a mutant gene can be replaced by adding another piece of DNA with the desired sequence, which will bind to the cut DNA template strand and become incorporated into the host

My first key question I think is important is authority. I think that they should not use CRISPR. I think this because of my religious belief. I think that god made us for who we are and using CRISPR would change who we would be as a person. God created each person for who they are. For example, if someone had autism but they took it away before the fetus is born then they are changing that fetus whole life that God had planned

The ability to engineer biological systems and organisms has an enormous potential for applications across basic science, medicine and biotechnology. Genome editing is a group of technologies that allow scientists the ability to change an organism’s DNA, which can provide better outcomes for health and disease control compared to natural immunity and mutations. Genome editing (gene editing) allows genetic material to be added, removed or altered at particular locations in the genome. A number of gene editing technologies have emerged in recent years with one of the most versatile and precise methods of genetic manipulation being Crispr-Cas9 (Steve scott,2016). The term Crispr-cas9, (clustered regular interspaced short palindromic repeats)

Biotechnology prompts a fear that humanity is gaining too much control over the choice of human evolution and destiny (McLean 1). CRISPR, “…the new fast, flexible, cheap way to manipulate the genetic code of life…” (Achenbach 1) exploits from the natural process used by ordinary bacteria to fend off against intrusive viruses while Cas (CRISPR-associated proteins), a set of enzymes, precisely snips DNA. CRISPR makes it simple to alter specific genes, resulting in many scientists beginning to use this new form of biotech for many of their experiments. Consequently, the editing of the

The CRISPR technology opens the door to more than a few unethical implications. This genetic engineering is not a technology limited to mature human cells, CRISPR can, and mostly likely will, be used to modify the genes of human embryos, effectively allowing the creation of a new class of modified humans, or what the co-inventor of CRISPR refers to as, “Designer Babies”. This class of modified humans will results in a gradual and irreversible evolution of the human species. The changes will start small, select families will have the power to change their child’s genetic makeup to prevent an imminent disease. But as time and the human understanding of genetic code progresses the temptation to use this technology for vanity will inevitably increase.

The power to genetically modify the human genome is being held captive even though it holds the opportunity to cure genetic diseases. The CRISPR method offers “unparalleled potential for modifying the human