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The Use Of Fenugreek Seeds As Previously Reported

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SFSE-G was prepared and characterized from the hydroalcoholic extract of fenugreek seeds as previously reported [15]. Two peaks namely peak A (trigoneoside Ib) (76%), and peak B (vicenin-1) (15%) were observed in HPLC at RT = 2.2 min and 3.2 min respectively. The corresponding compounds were isolated and characterized using TLC, 1HNMR, and 13CNMR analysis.
After an overnight fasting, liver fibrosis was induced by intratracheal administration of BLM hydrochloride (Biochem Pharmaceutical Industries Limited, India, 6 IU/kg in 0.9% NaCl) under anesthesia with 60 mg/kg ketamine hydrochloride and 5 mg/kg xylazine [16]. The rats in the normal and sham control group were subjected to the same procedure, but BLM was substituted by saline. The rats were randomly divided into following groups (n = 12) as follows:
Group I: Normal group: (N): Rats did not undergo any surgery and did not receive BLM. They were administered a single daily dose of distilled water (10 mg/kg), p.o. for 28 days.
Group II: Sham control group: (S): Rats were undergone surgery and received saline. They were administered a single daily dose of distilled water (10 mg/kg), p.o. for 28 days.
Group III: BLM control group: (BLM): Rats were undergone surgery and received the intratracheal administration of BLM. They were administered a single daily dose of distilled water (10 mg/kg), p.o. for 28 days.
Group IV: Methylprednisolone (10 mg/kg) treated group: [MP (10)]: Rats were undergone surgery and receive the
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