The Use of Stem Cells to Treat Myocardial Necrosis

These cells come from fetuses which is why stem cells are such a controversial issue. In order to actually use embryonic cells, they must be harvested from an unborn baby that is in the early stages of life. Embryonic cells have the ability to be all 220 types of tissues in the human body. “This makes them ideal for regenerating diseased heart tissue, repairing spinal cords, and replenishing brain cells”, Elizabeth Svoboda, an author in the publicized Popular Science magazine, illustrates in her article about stem cells (60). Embryonic cells have limitless possibilities in medical advancement. These cells can become whatever type of cell a doctor program them to be. With the use of embryonic stem cells, doctors can cure several diseases, as well as curing people who have suffered injuries, but research is being slowed down by the ethical dilemma of aborting a

STEM cell research according to scientists might be the key to saving lives due to organ failure, brain damage or even heart problems. The idea is stem cells provided by fetuses that have been aborted typically

"Embryonic stem cells are special because they are the only cells that can make all parts of the body,” said Douglas Melton, in an interactive videoconference available at athome.harvard.edu. The conference was hosted in New York and broadcasted to Cambridge, Washington D.C., and Naples, Florida on March 2, 2004. "Embryonic stem cells can do everything. So if you want to work on replenishing tissues, that’s where you go."

This new research uses the scaffolding technique combined with stem cells to grow a heart. The new breakthrough was made using poor quality donated hearts. There were first stripped of heart tissue, leaving only the scaffolding of the heart. All of the tissue must be gone so that a potential patient won't risk rejection.

Therefore, much of the critic’s arguments are invalid due to the fact that the embryo won’t develop into a child. Stem cells are the beginning of an enormous scientific breakthrough, a breakthrough that critics are simply putting off. Embryonic stem cells have the potential to treat some of the worst diseases we face today, such as cancer. Many critics argue that adult stem cells offer a good alternative. However, adult stem cells have become specialized and only have the ability to become specific type of tissue. Unlike adult stem cells, embryonic stem cells have the ability to create any type of cell within the body, as well as replicate themselves. This difference is proof alone that embryonic stem cells are vital to treating the more complex illnesses. Due to this, embryonic stem cells would create a larger bank of replacement cells and tissues. This is important because although there is organ and tissue donation, there is a higher demand for them than we have to supply. With embryonic stem cells, there would be more available treatment for patients with diseases such as macular degeneration, spinal cord injuries, heart disease, and more. In the case of heart disease, with the use of embryonic stem cells, healthy heart tissue could be generated in the lab and then transplanted. This would lead to a quicker treatment option than waiting for an available tissue and organ through

A few individuals with coronary illness and diabetes have gotten trial medications taking into account foundational cells disconnected from grown-up tissue, frequently from bone marrow, with shifting degrees of achievement. These mesenchymal stem cells, or MSCs, can develop into a few tissues including muscle, bone, ligament and fat yet there is no ensure that they will develop into heart muscle. This will left us with the answer to many people around the world why and how stem cells are stored.

In order to obtain relevant information to support this topic, databases including PubMed, Medline, UpToDate, and Google Scholar were used. Terms used in each search included and combined the following: mesenchymal stem cell, cardiac stem cells, HF, heart repair, ejection fraction, cardiac output, cardiac index, mortality.

After patients have gone through heart disease, like any other injury, therapeutic steps must be taken. Therapy and rehabilitation of damaged hearts has been improved through the utilization of stem cells. Therapy includes strengthening of the damaged area as to prevent the incident from reoccurring and getting the patient back to their normal life. Scientists, again, used rats that had had induced myocardial infarctions. This

Embryonic stem cells are repairing damaged tissues in the body. Scientists have find a way to replace damage hearts. The United States heart failure affects more than 400,000 people a year. With the use of stem cells can be used to reconstruct the heart

Rather than relying on surgical methods meant to replace these tissues, scientists are now beginning focus on new methods that actually allow the heart to repair and replace damaged tissue. In the June 29, 2006 edition of the journal entitled, Nature, Dr. Kathryn Ivey of the Gladstone Institute of Cardiovascular Disease explains, “the ability of circulating cells to produce factors that are sufficient to invoke cell survival or repair responses in damaged heart cells” remains a primary objective of research cardiologists. By manipulating synthetic compounds meant to catalyze the regeneration of tissue, the new experimental method of repairing heart muscles may be able to abandon surgical procedures altogether. While the vast majority of attention is being spent on the ability to use stem cell therapy to repair congenital heart defects, some scientists are exploring alternative possibilities in organisms like the

“Through the isolation and manipulation of cells, scientists are finding ways to identify young, regenerating ones that can be used to replace damaged of dead cells in diseased organs. This therapy is similar to the process of organ transplant, only the treatment consists of the transplantation of cells rather than organs. The cells that have shown by far the most promise of supplying diseased organs with healthy cells are called stem cells.” (Chapter Preface)

According to some researches, stem cell-based therapies have the potential to dramatically transform the treatment and prognosis of HF by achieving what would have been unthinkable only a few years ago. They also asserted that for the first time since cardiac transplantation, a therapy is being developed to eliminate the underlying cause of HF, not just to achieve damage control. In 2001, the first study of bone marrow cells in experimental myocardial infarction (MI) was published,9 within a year, this therapy had been applied in patients.10 In the setting of HF, it took only three years from the first use of stem cells (skeletal myoblasts) in an animal model to the first use of these cells in

Stem cells have emerged as one of the ways in which most diseases could be treated. Stem Cell therapy is defined as the use of stem cells to nurse or avert a disease (Siqueira, 50). Stem Cell therapy mostly utilizes bone marrow transplants but in the recent years, umbilical cord blood therapies have emerged. Research is currently ongoing to form various avenues for stem cells, and to make use of stem-cell therapeutics for conditions such as heart diseases and neurodegenerative diseases such as diabetes. In recent past, many people and organizations have accused Stem Cell therapy for not conforming to the virtues of human humanity mostly because of its contribution in human cloning and abortion debate. The main precepts of stem cell therapy

Rendering itself as a basic unit of growth and development, stem cells are essential in early life. They are small, unspecialized cells capable of reproducing and differentiating into different cell types. These cells can turn into a functional cell such as a muscle cell, organ-specific cell, brain cell, or a red blood cell. Despite controversy, stem cell research has given life back to suffering individuals and brought hope to the medical field. Along side many other major advancements of biology in the last century, stem cell research has taken off and found tremendous success just in the last fifteen years.

Stem cells can give rise to any tissue found in the body and thus provide nearly limitless potential for medical applications . Stem cells have the great potential to develop into many different cell types in the body during early life and growth. They serve as a repair system . Due to unlimited therapeutic applications of stem cells , they continue to be of great importance scientifically and