Barbiturates Essay

These medications have evolved and changed due to availability in the past few years. Cost has also had an impact on what medications are available to a dying patient. A patient self-administers an oral liquid suspension or a powdered mixed with a soft food such as applesauce. The mix of medications include barbiturates, chloral hydrate, and morphine which are compounded into a single dose prescription to facilitate death. Premedication is required prior to taking this final dose. The most common barbiturates are phenobarbital, pentobarbital or secobarbital. Phenobarbital is the longest acting and is typically used for seizures. Pentobarbital and secobarbital are used to sedate prior to surgery and are not as long acting as phenobarbital. Barbiturates effect the central nervous system. They are classified by their how long they take to effect and their duration of action. Barbiturates increase GABA (gaba amino-butyric acid) neurotransmissions in the brain. The increase in GABA causes drowsiness. They are highly addictive, and patients may become tolerant. The addiction is not an issue when a patient has reached this stage and does not need to be a concern. More importantly, if they have used them during the disease process as a sleep aid the patient may have built a tolerance and would require a higher dosage to be effective. Barbiturates do not provide pain relief, to provide pain relief a patient would need to reach a dose high enough to cause a comatose state. Chloral hydrate is a sleep aid or tranquilizer prior to surgery. This medication is quick

f. .stimulants can cause enhanced brain activity increase and llertness in energy elevated blood pressure increase heart rate increase respiration and sleep deprivation…. Ultimately these three drugs possess the same long term affect when abused; high potential for physical dependence and addiction.

Individuals taking tricyclic antidepressants (TCA) for major depression sometimes use these same drugs to attempt suicide. Unresolved depression can lead to individuals taking further drastic measures to deal with their emotional dissatisfaction. While TCA’s may not always be the most lethal drugs, an overdose can still have life threatening consequences. Following overdose of TCA’s, early identification of predictive symptoms for life endangering seizures and ventricular arrhythmias could allow healthcare providers the opportunity to take preventative measures and thus save lives.

The body, through tolerance, becomes accustomed to the effects of the drug causing a change in the functioning of the reward center in the brain. Neurotransmitters in the brain, at this point, do not function normally and the body “needs” the drug to achieve balance within the system.

enters the blood stream in just a matter of seconds of using this drug. When eating or drinking

side effects of analeptics are increased heart rate, agitation and the kind of paranoia and disorientation

Individuals all over the world suffer with clinical depression, which affect their quality of life. Depression usually affects a person’s emotions, thoughts, behaviors and overall physical health. Symptoms include sadness, guilt, moodiness, loss of interest, with drawling from people, changes in sleep, decrease in sex drive, and thoughts of self-harm or suicide. The common antidepressants take at least a two-week period to take effect; that two-week period is a critical time where a patient can increase their symptoms and experience suicidal depression. The party drug, known as ketamine has recently made a big impression for neuroscientists trying to formulate a medication to help those who suffer from clinical depression in a rapid time frame. A key element in the advancement for faster medications is realizing how and why, ketamine works so quickly, in comparison to the other generic drugs that are prescribed. According to Newport, a dose of the nonselective N-methyl-D-aspartate receptor antagonist ketamine can produce a constant antidepressant effect within hours. With the amount of experiments being conducted to expand the knowledge of ketamine, the objective is to find a solution that can be used to relieve the patients who experience serious symptoms in the fastest time possible.

While medication may be taken worldwide and is much more commonly used for depression, it isn’t always the best solution. Causing potential problems such as nausea, headaches, insomnia and even increased suicide rate. In comparison, therapy allows connection, interaction, someone to trust, and overall monitoring of the patient's progress. Which option is more beneficial to the patients? Medication or therapy? The research done will help determine that option. This option will be very beneficial to a growing community around the world. This research project aims to explore the risk of overdosing when treating depression with antidepressants. Taking medication while being diagnosed with depression although may be helpful, it can be dangerous and life threatening.

Historically, the use of drugs as fixers of the world's private ills has run into serious, if unanticipated, snags. At the turn of the century, the medical community thought that Cocaine was a completely appropriate, nonaddictive drug, and widely prescribed it. In the 1950s and '60s, first barbiturates and then amphetimines were recommended for various psychological ailments. It

A person may be suffering from depressive symptoms and use narcotics with the hope of acquiring some kind of relief. Depressive symptoms can develop as a result of using mind altering substances or as part of withdrawal symptoms when taking breaks from drugs. Low mood in withdrawal can be short and self-limiting, though sometimes it may lead to a very serious and prolonged depressive illness. A person will take drugs to escape or forget a problem in

The pertinent findings will be explained, and their implications on future anti-depressants will be addressed.

There must be special attention toward the patient's addiction history before these agents are prescribed. An understanding of the toxicity and side effects of benzodiazepines, abuse patterns and alternative anxiolytic and hypnotic agents may help clinicians to be safe from issues of medico legal case.

Used alone or in combination with other CNS depressants may lead fatal respiratory depression and to physical and psychological dependence.

The efficacy and safety of the drug in patients under the age of 18 years is not established. With renal / hepatic insufficiency and long-term treatment, control over the picture of peripheral blood and liver enzymes is necessary. Patients who did not take previously psychoactive drugs respond to the drug at lower doses compared to patients taking antidepressants, anxiolytics or alcohol. With endogenous depression, alprazolam can be used in combination with antidepressants. With the use of alprazolam, patients with depression have seen cases of hypomanic and manic development. Like other benzodiazepines, alprazolam has the ability to induce drug dependence in long-term admission in large doses (more than 4 mg / day). With a sudden discontinuation of alprazolam, there may be comeback syndromes, such as depression, irritability, insomnia, increased sweating, especially with prolonged admission (more than 8-12 weeks). When patients develop such unusual reactions as increased aggressiveness, acute excitations, feelings of fear, thoughts of suicide, hallucinations, increased muscle cramps, difficult sleep, superficial sleep, treatment should be discontinued. During pregnancy Xanax is very dangerous due to its toxic effect on the fetus and increases the risk of congenital malformations when applied in the first trimester of pregnancy. Admission of therapeutic doses in later periods

They slow the body down. They relax, tranquilize, relieve pain and induce sleep. One may say and do things that they would never do under normal circumstances. When these depressants bare abused they can slow do0wm body functions such as breathing to an extent that a person may pass out or even lapse into a coma.