Thyroid Gland ( Tg )

1523 WordsNov 4, 20167 Pages
Introduction Thyroid gland (TG) secretes thyroxin and triiodothyronine (Garber et al., 2012). Its main function is to make hormones and main job is to produce hormones T4 and T3 (Mortimer, 2011). To do this the human TG has to take a form of iodine from the bloodstream into the human TG (Garber et al., 2012). This substance then undergoes a numerous of different chemical reactions which resulted in the production of T3 and T4 (Mortimer, 2011). In order to make T4 and T3, TG needs iodine, a substance found in the food, both T4 and T3 contains four atoms of iodine. T4 is then converted to T3 through the cells and tissues of the human body. More active hormone is T3, because it influences the activity of all the cells and tissues of the human body. Thyroid is controlled by hormones produced by hypothalamus and pituitary. Besides, these secreted hormones in the TG are essential for normal growth, better development and metabolic function. Thyrotropin-releasing hormone (TRH) stimulates the pituitary to secrete TSH which in turn acts on the TG to cause synthesis and secretion of thyroid hormones. Altered thyroid function is common and respectively the release of TRH and TSH enable feedback of the hormones on the pituitary and hypothalamus to inhibit synthesis. For example, a prevalence of hypothyroidism has been reported in the literature that up to ten percentage in the general population is possible expected to occur. It is an essential to have accurate assays of thyroid
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