Horses that are used for professional showing or athletic competitions are inclined to receive an injury involving tendons or ligaments, which can be career or life ending depending on the severity. The injured soft tissue usually has a poor blood supply so they are prone to healing with scar tissue. This makes the healed area less elastic and decreases the function of the tendon or ligament, and re-injury to the soft tissue increases. Another issue associated with soft tissue injuries is the inflammation of a tendon called tendonitis that can be seen in 43% of horses returning to work (Alves AG, Stewart AA, et al, 2011). Because of these issues regenerative therapy has been considered a more effective way to stimulate healing for orthopedic injuries. …show more content…
The focus of regenerative medicine is to the combine effects of a cell source, scaffold support, and anabolic stimulus to enable healing to the damaged tissue. One of the options for a cell source would be tenocytes; however, this would leave a lesion at the donor site from a biopsy, which cannot be done to a horse’s flexor tendon without additional consequences. Also, cells derived from different tendons show different characteristics compromising their effectiveness. Another option for differentiated fibroblasts includes dermal and ligament fibroblasts, but they have different cell characteristics that may not be useful in tendon repair. Therefore, stem cells are being seen as the greatest option for soft tissue repairing and healing (Herthel
Today there are hundreds of types of therapy programs for those with physical and psychological disorders. Though perhaps one of the most versatile, easily accessible types of therapies can be done through the use of a horse. Hippotherapy, specifically defined, is a “physical therapy in which a patient (as one affected with cerebral palsy or multiple sclerosis) sits or lies on the back of a horse for the therapeutic effect of the horse's movement” (1). In the 5th century, Hippocrates revealed his belief that horses were healers. He described horseback riding as a universal exercise with a healing rhythm.
Stretched tendons, torn muscles, and sprained joints are all things that can be healed by vets or even better equine massage therapists. Equine massage therapy is a unique industry within the horse world. Massage therapists are hired to relax horses after hard performance, and help them recover from any various injury they may acquire. Equine injuries are inevitable; recovering from an injury can be very complicated and costly; however there is an alternative. Massage therapy used as a rehabilitation technique can strengthen the injury to heal correctly without future complications, keep the horses muscles relaxed and operating correctly, and assisting the horse to recover in a natural state with no medications. Healing an injury can take many weeks or even months to accomplish, but with massage therapy the healing can be done very efficiently.
This will result in the scar starting to look organised. If the injury has been treated correctly then your should have full strength back with the injured area becoming full fictional again. The type 3 fibres (also known as collagen fibres) that are put in place for a temporary basis are replaced by type 1 fibres, this is because they are a lot stronger than type 3 so they are able to keep the scar tissue in place so help get the injured area back to full strength. This phase is a long recovery process and can take up to 12 months before it has healed properly. Functional rehabilitation helps assist with this phase of the recovery, this is because you need to challenge the injured area to help it fully recover, this can be done before you are able to play again.
A fall can change your day, your week, and maybe even your life. These injuries can often happen anywhere and to anyone, which can be frightening in their suddenness, and cause severe pain and injury. Falls are the most common variety of accidental injuries. However, a fall is not a type of injury, it is a cause.
Superficial digital flexor tendon (SDFT) injuries are a significant cause of lameness and diminished performance within the equine athletic industry, with a reported incidence of 8 to 43% in Thoroughbred racehorses (Dowling, 2000). This is due to these injuries’ high prevalence, extended recovery period, and high rate of recurrence (Guercio, 2015). SDFT injuries are slow healing, with 20-60% of injured race horses returning to full athletic ability, but with up to 80% of injured racehorses succumbing to re-injury (Dowling, 2000). This tendency to heal slowly, and the formation of mechanically inferior extracellular matrix, is likely due to the fact that tendons are minimally vascularized, present cells with diminished mitotic activity, and
In this essay we will discuss the four different phases of the soft tissue healing process and also explain all the components of each particular phase and how it functions. This will also include sport therapeutic interventions that may contribute to the healing process and that may maximise healing of soft tissue.
carolinensis is such a popular animal model that many research articles have been published around the experimentation. Elizabeth Hutchins (2014) focused on the regenerative abilities found in the lizard’s tail and the cells that worked specifically during the process. The study used a variety of experimental methods to collect data including; applying pressure to their tails until they were released, this site of release was sampled and analysed with RNA sequencing, immunohistochemistry, etc. to isolate different cells, and therefore regenerative processes.4 Ultimately, the regenerative tail of A. carolinensis showed a multitude of genes being activated that are specific to wound healing and musculoskeletal development pathways.4 Skeletal and cartilage growth occurred along the entire length of the tail and there was no localised bundle of proliferative cells, alongside a highly vascular distal end;4 all different mechanisms to the localised, distally avascular mechanism found in anamniotic vertebrates.4 This stem and progenitor cell based process is therefore quite different to the previously studied ‘blastema-based model’ of regeneration in the commonly studied anamniotes: zebrafish and salamanders, providing insight into application to further medical regenerative possibilities in humans.4 Using A. carolinensis provided a prominent advantage to the study due to the previously highly developed genetic knowledge, ease of replenishing populations, and habitual
Traumatic acute events leading to tendon losses as well as ruptures related to degenerative tendinopathy require a replacement of the damaged tissue. Yet in these cases, the healing process does not efficiently restore the native tendon structure and function, despite the surgical intervention with a high rate of re-tear (Sharma and Maffulli, 2006; Andarawis-Puri et al. 2015). Nowadays, tendon autografts are the common choice to reconstruct the tendon integrity, despite their limited supply, high donor-site morbidity, and poor functional outcomes ( Gazdag et al., 1995; Lovati et al., 2016). To overcome these limitations, tissue engineering widely investigated the generation of cell seeded scaffolds to promote regeneration and implant-tissue
In the early 20th century a Russian American named Alexander A. Maximow, established the theory that every cell comes from a precursor cell. Maximow was deeply involved in histology, the study of plant and animal tissue. Being the first to show that blood cells come from a common precursor cell, he is given the most credit in discovering what is known as stem cells (source #7). Stem cells have the ability to change into other cells such as blood, bone, tissue, and muscle cells. Researchers are trying to better understand these foundation cells to create cures and treatments for diseases and injuries. The report will be based on two articles. The next point will evaluate each source. Afterwards, the following information will
Soft tissue injuries are most common wounds in sport. These refer to those tissues in your body that attach, support and enclose structures of your body, comprising the ligaments, muscles, as well as tendons. Ordinary injuries to flexible tissues that you may have heard of comprise muscular strains, ligament twists and bruises. With the beginning of each sport season, it is appropriate that you go over the suggested and timely management of the soft tissue injuries. It is essential to give your body the finest possibility of a rapid recovery by striving to limit additional damage and encourage the remedial process.
For example, the study involving doxycycline discussed earlier was merely a pilot study and, therefore, is supposed to be regarded as a preliminary analysis. This study is meant to provide important information to orient more specific future research studies. As is the case with many biomedical research studies, this experiment is done using non-human subjects to avoid unknown, potentially harmful results to be projected on humans. This fact adds to the mystery surrounding the Achilles tendon; although rats are a good model system for humans, there is a great amount of generalizability done when transferring the data and results from rats to be interpreted for humans. In terms of procedure, noteworthy discrepancies exist in the discussed study. For example, the administration of doxycycline to the rats started one day prior to the induced tendon laceration5. This is a distortion of reality because in humans we do not know when we will receive an injury to our Achilles tendon. Furthermore, the injury to the tendon in the rats was surgically induced using a knife5. Again, this is unrealistic for humans because Achilles tendon injuries do not occur naturally by way of knife but rather are usually traumatic and do not yield the same clean cut that was obtained in this study. This is important to note because the way the injury was induced could impact the healing process
great increases in host regeneration were reported in skeletal muscles injected with NAC-treated MDSCs in comparison to all other muscle injection groups. directions in scar tissue formation were the inverse of the directions in host muscle regeneration.
Tunica adventitia or externa (the outer layer): a layer of connective tissue that attach the vessels to the surrounding
Therefore, understanding the development could lead us to understanding of regeneration of the natural tendon-to-bone insertion
The brutality of mixed martial arts, American football, the repetitive nature of a pitching arm or even jumping up for rebounds while enduring contact from an opposing player, leaves an athletes body a wreck. Rest alone will not heal the body completely, and if scar adhesions have formed, imbalances in the fascial system or flexibility has been compromised so fascia needs to be addressed.