Toxicology of Propoxur

1815 WordsApr 12, 20138 Pages
------------------------------------------------- Toxicology of Propoxur ------------------------------------------------- Pharmacology 1 – Group B3A List of Contibutors: Ali Mourad 10747691 16/4/2013 ------------------------------------------------- Toxicology of Propoxur ------------------------------------------------- Pharmacology 1 – Group B3A List of Contibutors: Ali Mourad 10747691 16/4/2013 ------------------------------------------------- Abstract The purpose of this analysis is to investigate the effect of application of propoxur (a carbamate insecticide) on the American cockroach. From experimental observations, it has been concluded that the amount of propoxur needed to kill 50% of the test subjects (referred to as LD50) was…show more content…
From the data given we were able to construct table 3 where the Mean Mortality, Mortality Percentage and Probit were calculated. Table 2: Group results of cockroach deaths results as per concentration of propoxur ( % w/v). Group B3A | Control | 0.01% | 0.01% | 0.02% | 0.05% | 0.10% | Sample 1 | 0 | 0 | 1 | 1 | 3 | 5 | Sample 2 | 0 | 0 | 2 | 1 | 4 | 5 | Table 3: Compiled Data and Analysis of class results. Concentration | Total Number | Mean Mortality | Mortality (%) | Probit | Control | 5 | 0 | 0 | 0 | 0.005 | 5 | 0.29 | 5 | 3.36 | 0.01 | 5 | 1.14 | 22 | 4.23 | 0.02 | 5 | 1.79 | 35 | 4.61 | 0.05 | 5 | 3.79 | 75 | 5.67 | 0.1 | 5 | 4.86 | 97 | 7.75 | Tabulated statistical data from the values obtained from Table 1. Probit was calculated to construct Graphs 1 and 2 thus a linear relationship can be formed and LD50 calculated. Graph 1: Comparison between Class Mortality results and Group Mortality. Graph 2: Probit Mortality rate (percent) plotted against concentrations of propoxur ( % w/v). Results were obtained and a probit regression analysis was constructed. From this, statistical data is used to determine the LD50 as per Concentration. P-Values were also determined with 95% Confidence Intervals. Regression Table Standard Variable Coef Error Z P

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