Trade and Generic Name, Drug Classification and Mechanism of Action

1064 Words Feb 24th, 2018 4 Pages
Metformin is classified as a biguanide and antidiabetic medication. Its therapeutic classification is an antihyperglycemic. Metformin, which is the drug’s generic name, is also known under its trade names: Fortamet, Glucophage, Glucophage XR, Glumetza and Riomet. Metformin is an oral hypoglycemic medication and has three main actions: Metofrmin increases the binding of insulin to insulin receptors in skeletal muscles and fat, which works to improve tissue sensitivity to insulin. Through this action, glucose is able to be transported into skeletal muscles and fat and the body is able to use glucose to function properly. Metformin also suppresses gluconeogenesis, which is the production of glucose from non-carbohydrate sources such as fat and protein. Metformin also prevents the liver from converting stored glycogen into glucose. All these actions work together to lower the level of blood sugar and also lower the Hemoglobin A1C value, ensuring diabetics have better control of their blood sugar.

Indication for Use and Contraindications Metformin is used to treat patients with Type 2 diabetes in addition with proper diet and exercise. Metformin is contraindicated in patients with hypersensitivity to metformin, hepatic or cardiopulmonary insufficiency, alcoholics, patients with multiple infections, acute myocardial infarction,…

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